2BTW


Conserved Protein Domain Family
Phytochelatin

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pfam05023: Phytochelatin 
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Phytochelatin synthase
Phytochelatin synthase is the enzyme responsible for the synthesis of heavy-metal-binding peptides (phytochelatins) from glutathione and related thiols. The crystal structure of a member of this family shows it to possess a papain fold. The enzyme catalyzes the deglycination of a GSH donor molecule. The enzyme contains a catalytic triad of cysteine, histidine and aspartate residues.
Statistics
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PSSM-Id: 398616
Aligned: 67 rows
Threshold Bit Score: 175.815
Threshold Setting Gi: 81734489
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2BTW_A            36 QTLTLS-PNLIGFNSNEGEKLLLTSRSR---EDFFPLSXQFVTQVNQAYCGVASIIXVLNSL--GINa------------ 97  Nostoc sp. ...
Q21NE9            77 DDWSLP-ENMVDLRSEEGQTRLLECsy---cEDYPTLATAYLTQATQTFCGLASTTMVLNA-----Daesr--------- 138 Saccharopha...
jgi:Pnuc_0547     21 lTNAFP-ADLVYINTTAGSERLLHSTHN---RQYFALASYVDTQERVTFCGISSMSATLNSLptVVR------------- 83  Polynucleob...
Q13MK8            31 GPLPVP-PNLVALTQPSGQKRLTGSASN---QSYWPLSQYFETQRNEAYCSVATSVMALNAL--GIRr------------ 92  Paraburkhol...
EDQ84778          32 REMPLP-PELIASNSSAGVQLLLSAQAQgyaEPFWQLSMTYTTQQNQAYCSVASSAMSLNAL--GVPa------------ 96  Monosiga br...
jgi:MICPUN_61050  29 tlLPVP-TDDIPLNSTEGERLLRDCTHY----PGVDVLMHLATQRNQAFCSAATAATLLNAMarTVTa------------ 91  Micromonas ...
jgi:Cyagr_2386    12 aagRLR-AAPIPLMQPAGMELLVASGER---ADYGPLAEQFLTQANLAYCGVASAAMVLNSL--AVPa------------ 73  Cyanobium g...
Q7V6X1            36 SNPALA-EKLVPITTSEGMVLLQRSKSV---SDYGSLMEAFLTQSNLAYCGVASAVMVLNSL--AIPa------------ 97  Prochloroco...
Q47GT9            26 ATAPVRiRALLPFASAEGLDRLARATAR---SDFAPLANQFEAQVTIAFCGPTSAAIVLNAL----Dpqgagaprdrsrl 98  Dechloromon...
Q63T30            24 QPLPLP-AGLIDLGSLAGEQMLAESGAR---SAYASLGSHFVTQKTQSYCGVASLVMVLNAL--RVPa------------ 85  Burkholderi...
2BTW_A            98 -------PETAQYSPYRVFTQDNFfSNeKtk--------avIAPEVVARQGXTLDELGRLIASYg-VKVKVNHAs--dTN 159 Nostoc sp. ...
Q21NE9           139 ----kwrPVTQPYQPFNFYTQCNLlNDeVre---------hIDVAKVLNEGMELNEIFFVVKNQp-SVVEAYCQhatsaq 204 Saccharopha...
jgi:Pnuc_0547     84 -------PITPELAPHPYFTEDSIfNEaTtk---------iKSRDDVLKSGLTLEQIGLYLTALk-ANPKVYYGs--dLT 144 Polynucleob...
Q13MK8            93 -------PESTQYPDFPFFSQDDFfRg-Idp--------qvANAAQVSREGMTLDQLGTALQAFp-IDVRKYHAs--dLS 153 Paraburkhol...
EDQ84778          97 -------PVDAVYSPYNYFTQSDVfTPcAvn--------qnITEAYVATHGLTLAQAHALLACFpaVDAQLHHAgqagAD 161 Monosiga br...
jgi:MICPUN_61050  92 -------PVDVEFAPYPYFTQRSIlQDaCvrrvpthedgtlMSVKFLATHGATLHEWATYLSCF--AEVEHVHAe--vST 160 Micromonas ...
jgi:Cyagr_2386    74 -------PPVPGYGRYRFWTQENVfDVpAgs--------qvVSAEVVRRQGMTLTELAGLLAAHg-VKADAIHGd--rLS 135 Cyanobium g...
Q7V6X1            98 -------PPVDGFRNYHFWTQDNIfNSdSsq--------vvISPAKIRRQGMTLQELQNLLSHHg-VSSKRLHGd--iLS 159 Prochloroco...
Q47GT9            99 lpadaryLPENLELTVRRHTQESViATgRktraqvfgepseIKGKVLRDGGYQLRQLDELLKAHn-MDTRLVIAde-qMS 176 Dechloromon...
Q63T30            86 -------PAAAQYPPFHYFTQDNVlGd-Ate--------riRPRALIERHGMTLDQLGALANALg-ASGDVRHAs--dVS 146 Burkholderi...
2BTW_A           160 -------------------IEDFRKQVAENLKQd-----gNFVIVNYLRKEIGQERGGHISPLAAYNEQTDRFLIXDVSR 215 Nostoc sp. ...
Q21NE9           205 nkgelpasdaphncgvdqdyntFMKTITNALNTp-----rHYVIANFAGAPSPERG-GHFSPIAAYHKASDSFLIMDVAR 278 Saccharopha...
jgi:Pnuc_0547    145 -------------------VAELRKVIQSSLANp-----yQRVMVDFDRQALHQLGNGHFSPIGAYDSKSDSVLILDVAK 200 Polynucleob...
Q13MK8           154 -------------------LHQFRDLVRTTTGHd-----dRFVLLNFRRIEIGETGGGHWSPLAAYDATSDSALLLDVAR 209 Paraburkhol...
EDQ84778         162 -------------------LAAFSRDLNATSQGt-----hALIIINFLRTGMHQEGGGHFSPLAAYDPVSDRILVLDVAR 217 Monosiga br...
jgi:MICPUN_61050 161 -------------------AAAFRDVVKAVFPTtrgakaeKFVGINFLRTGVGEDGGGHMSPIAAYDETADRVLIADVSR 221 Micromonas ...
jgi:Cyagr_2386   136 -------------------LEQFRALLRANLSQp-----gDRLLANYLRPSLGQAGGGHIAPLAAFHAPSDRVLILDVAR 191 Cyanobium g...
Q7V6X1           160 -------------------LQAFRSLIKANLDDs-----sDRLIVNYDRKVIGQKGGGHFSPLAAYDAVTDKVLILDVAR 215 Prochloroco...
Q47GT9           177 -------------------EAEIRRDLIDNLGRa-----gDFVIVNYQRRAVGQTGGGHISPLGAYDAESDSVLVLDVNP 232 Dechloromon...
Q63T30           147 -------------------VDVFRADAIAHLGRp-----gRYVLVNYLRSRLGQQTGGHISPLGAYDAAADRFLILDVSR 202 Burkholderi...
2BTW_A           216 YKYPPVWVKTTDLWKAXNTVDSV-S-QKTRGF 245 Nostoc sp. PCC 7120 = FACHB-418
Q21NE9           279 YKYPPFWISSKELWQAMQKIDSG-S-GKARGY 308 Saccharophagus degradans 2-40
jgi:Pnuc_0547    201 YKYPPFWVTTSDLLASLKTIDPD-S-GRSRGI 230 Polynucleobacter asymbioticus QLW-P1DMWA-1
Q13MK8           210 YKYPAVWVPVAQLYAAALAVDSV-S-GLSRGI 239 Paraburkholderia xenovorans LB400
EDQ84778         218 YKYPSFWATRQDVFNAMNTIDSS-S-QQTRGW 247 Monosiga brevicollis MX1
jgi:MICPUN_61050 222 YKYPPVWARLTSVYGAMNTTDDA-S-GKSRGW 251 Micromonas commoda
jgi:Cyagr_2386   192 YRYPSVWVPVADLWAAIRTIDST-S-GRSRGL 221 Cyanobium gracile PCC 6307
Q7V6X1           216 YRYPSVWVKTHDLWRAMRTLDGI-S-GLQRGI 245 Prochlorococcus marinus str. MIT 9313
Q47GT9           233 SYHPWVWMPLATLIQGMRTRDVAeN----RGY 260 Dechloromonas aromatica RCB
Q63T30           203 YKYPPVWVTTADLYAAMNTPDAD-SgGRSRGY 233 Burkholderia pseudomallei
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