2ODF


Conserved Protein Domain Family
FGase

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pfam05013: FGase 
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N-formylglutamate amidohydrolase
Formylglutamate amidohydrolase (FGase) catalyzes the terminal reaction in the five-step pathway for histidine utilisation in Pseudomonas putida. By this action, N-formyl-L-glutamate (FG) is hydrolyzed to produce L-glutamate plus formate.
Statistics
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PSSM-Id: 398607
Aligned: 277 rows
Threshold Bit Score: 69.5262
Threshold Setting Gi: 504913907
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2ODF_G              25 GDVLLVCEHASATIPQKYgt---lgLSADVLSSHAAWDPGALAVARLLSEkfh--atlVYQRFSRLVYDCNRPP-ESPSA 98  Agrobacte...
WP_005309262        20 SPVILHVPHSARAVPEDVragivldDDALRLELDHITDSHTAEIAAGAAGsatvapwrFVNGLSRLVVDPERFPdEREEM 99  Streptomy...
Q9KZF4              17 SPVILHVPHSSREIPAGVrsgivlsDAELERELDHMTDSHTAEIAGRAAGlagltpwrFVNRVSRLVVDPERFPdEREEM 96  Streptomy...
WP_023545183        18 SPVLLHVPHSARGIPAEArrgivldDGALERELDHITDAHTAELAERAAAlaavrpwrFVNRLSRLVVDPERFPdEREEM 97  Streptomy...
CeBiTec:B446_31270  17 SPVLLHVPHSARAIPGDVragitldDAGLERELDLITDAHTAEIAERAAApaglrpwrFVNRLSRLVVDPERFPdEREEM 96  Streptomy...
CDA68514             5 DPILIHVPHAATYIPKEElqy--fvtPNLERELMVMTDHFTDDLFDadc-------emLRFPISRLVCDPERFRdDEKEI 75  Clostridi...
CDB04396            34 kNILLHIPHSSFSFPSGSnh----sFNDLDNEEKLLIDYYTDELFVPQKEteh--igtIVFPYCRLFCDVERLInDPL-- 105 Prevotell...
CCX41160             6 phFVVHIPHSSLYIPEEErktfllsDAALFAEQRRMTDTFCDELYEDGErfp----vrVVAPVSRLVCDVERFRnDADEP 81  Clostridi...
dbos:SAR116_1277     1 mnCVFHIPHASTVIPEEYlqhfllnDEKLNEEILKMTDHYTDQLFEFDTitq----ktLKFPVSRLLVDPERFVsDSEEV 76  Candidatu...
WP_014108594         1 ----mHIPHASTHIPTDDidqficsEVELKNEINAITDHFTDWLVKPLEVcne---nrIIAPVSRLLVDMERFDdDSLET 73  Glaciecol...
2ODF_G              99 MpVKSEIYDIPGNfdld---------eaerFARTSALYVPFHDRVSEIIAERQ-AaGRKVVVVTIHSFT----------- 157 Agrobacte...
WP_005309262       100 --RAVGMGAVYTRtthreql---rpsafdpAGLIADYFVPYARAVTEAVDARLdA-VGRAVVIDVHSYPteplpyelhgd 173 Streptomy...
Q9KZF4              97 --AAVGMGAVYTRtshreel---rradtdpGPLIERYFRPYARAMTEAVADRLaA-TGRAVIVDVHSYPaqplpyelhgg 170 Streptomy...
WP_023545183        98 --TAVGMGAVYTRtthrael---rpadadpEPLLARYFRPYARAMAEAVADRLaA-TGRAVVIDVHSYPseplpyelhgd 171 Streptomy...
CeBiTec:B446_31270  97 --LAVGMGAVYTRtthggel---rpadtdpGPLVERYFRPYARAMTEAVAGRLaA-TGRAVVIDVHSYParalpyelhgs 170 Streptomy...
CDA68514            76 M-AKRGMGAVYTScsdcnelr--ripdehkEEILLKYYDRHHRMFEEAVTGKLeE-YGCCLIIDGHSFYpsplpyemdqg 151 Clostridi...
CDB04396           106 --EKDGLGISYVRevptgrysstfrsfsskEEAFIQ-YVDYHSA----VTKKLfAmGKNTLLIDCHSFSnipnll--nsn 176 Prevotell...
CCX41160            82 C-AKQGQGLMYVRtsfgkqlr--kndpalrQHILDSYYDPHHARLTAAVAHALeT-TGRCTILDGHSFHswypprl-kcl 156 Clostridi...
dbos:SAR116_1277    77 M-SKVGMGCIYEKthngksl---khgskirDELIRRYYQPHHERFTDMVDECLkL-NSKCLIVDCHSFPknplpyeliqe 151 Candidatu...
WP_014108594        74 M-SQVGMGVIYEKgsqrqtir-rdltqlerSELLKKYYYSHHKLLESRAESLVkK-YGKIIIIDVHSYPstalpyeldqt 150 Glaciecol...
2ODF_G             158 ---PVYHgrfreveIGILH-----DndsrLADAMLAGAe--GA-SLTVRRNDPYGPedgvtHTLRLHAL--PDGLLNVMI 224 Agrobacte...
WP_005309262       174 gprPPIC-------LGTDSfhtppE----LLAAARKAFsgfGG----TGLDSPFAG-----TYVPLRHYgkDRRVGALMI 233 Streptomy...
Q9KZF4             171 gprPPVC-------LGTDAfhtppG----LLAAAREAFapcGE----TGLDSPFSG-----TYVPLDFYgtRSEVGALMV 230 Streptomy...
WP_023545183       172 glrPPVC-------LGTDAfhtppE----LAEAARTAFavfGE----TGLDSPFAG-----TYVPLEFHgtDARVGALMV 231 Streptomy...
CeBiTec:B446_31270 171 gprPPVC-------LGTDSfhtppE----LREAARRAFsacGA----TGLDSPFSG-----TYVPLEYYgrDRRVSALMV 230 Streptomy...
CDA68514           152 eyrPDIC-------IGTDAyhtpaW----LACFICHYF---QKhGYETDLNRPFSG-----AIVPEKYYnrERRVISIMI 212 Clostridi...
CDB04396           177 ppdIDIC-------IGYNDdatcpDn--vVIGNIVHHF---ESlGYKVGINKPFSNsk--tFSVPMKYH-------SVMI 235 Prevotell...
CCX41160           157 fdrPDVC-------IGTDAfhtprD----LRDALVEHV---RNaGLHVRVNTPYSG-----AITPLCYYgkEKRVISVMI 217 Clostridi...
dbos:SAR116_1277   152 pnrAEIC-------IGTDGfhtpdW----LSKHLVDDF---RDsGFSVAINKPFSG-----SIVPTAHWqrKKEVSSVMI 212 Candidatu...
WP_014108594       151 lprPEVC-------IGCCDfhtpkR----LESGIVSAF---EQeGFDVAVNTPFSG-----TLVPSKFWrtSKNVMGFMI 211 Glaciecol...
2ODF_G             225 EIRNDLIA 232 Agrobacterium fabrum str. C58
WP_005309262       234 EIRRDVYM 241 Streptomyces pristinaespiralis
Q9KZF4             231 EIRRDTYM 238 Streptomyces coelicolor
WP_023545183       232 EIRRDVYM 239 Streptomyces roseochromogenus
CeBiTec:B446_31270 231 EIRRDTYM 238 Streptomyces collinus Tu 365
CDA68514           213 EINRGLYM 220 Clostridium sp. CAG:510
CDB04396           236 EVNKRLYM 243 Prevotella sp. CAG:520
CCX41160           218 EINRKLYM 225 Clostridium sp. CAG:1024
dbos:SAR116_1277   213 EIRRDLYM 220 Candidatus Puniceispirillum marinum IMCC1322
WP_014108594       212 EIRRDVYM 219 Glaciecola nitratireducens
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