2Q7S,2ODF


Conserved Protein Domain Family
FGase
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pfam05013: FGase (This model is not part of the current CDD release)
N-formylglutamate amidohydrolase
Formylglutamate amidohydrolase (FGase) catalyzes the terminal reaction in the five-step pathway for histidine utilisation in Pseudomonas putida. By this action, N-formyl-L-glutamate (FG) is hydrolyzed to produce L-glutamate plus formate.
Links
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Statistics
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PSSM-Id: 516571
Aligned: 197 rows
Threshold Bit Score: 74.5472
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2Q7S_A        24 LPLVCDSPHSGTFYPADFGA-------------VVAPERLRGGEDTHVDALWE-AVprvGGTL-LAATFPRVYIDPNRXL 88  Cupriavidus pin...
WP_013159623   3 LPALVITPHSSFQVPAEVLAemlgerfydslarQARLDWLFREGDPHTEVLFHtPE----AHP-LQAPFSRFVVDLNRDr 77  Allomeiothermus...
WP_012693495   6 DALLVLTPHPSGALPADVLRdmlgeemfdtprrEALLRAVFLDGDAYTELIYHvPG----ARH-LQASWSRFAADLNRDr 80  Deinococcus des...
Q9RUI9         5 DDLLILAPHPSGQLPADVLLamlgddafdtekrEAFLRRVFFEGDPYTDLIYAvPG----ARF-LQAPWSRFAVDLNRGr 79  Deinococcus rad...
WP_011530748   6 dCLLILAPHASGALPADVLRemlgedafdlnkrAAFLTRLFQEGDPYTDLIYAvPG----ARY-LEAPWSRFAADLNREc 80  Deinococcus geo...
WP_012106178   3 YPFLISIPHGGTEIPKEVAGr-----------fALTDQELLWYCDPETRILFDfGR---SVECtIDTPVSRMVVDLNRPP 68  Methanoregula b...
WP_015286524   5 YPFLISIPHGGTRVPPELDGr-----------lQLGRKDIQYYSDPDTRKLFGfGD---RVAArIEAEISRMVIDLNRPP 70  Methanoregula f...
WP_012064822   8 LPMLISVPHGGMTIPEVLQKk-----------cLIDPKGISMDGDTWARELYDfRD---LVEEyVDTDIARLVVDMNRNH 73  Alkaliphilus me...
WP_013488884   9 LPLVISVPHGGLEIPDNLKGc-----------cLLSEEDILLDSDTFTRELYDlKD---VVEEyIDTDIARIVVDLNRSA 74  Evansella cellu...
WP_012215386   4 FPVLLSIPHGGLKKPAELDGh-----------lTITNKDLFDDADPFVIELYDlGD---KVQRvIKTDIARAFVDLNRSL 69  Nitrosopumilus ...

2Q7S_A        89 DDIdpaqlEgpwptplapgektRLGYGLIWSNVDAATPIYDR---KLTVAEVQRRINRYYRPYHAALTEAVEGayqrFGA 165 Cupriavidus pin...
WP_013159623  78 -------eE-------------AGANGVIKLTDFEGRPLYPSg-fALDAQKREERLRRYWDSFHAEIERMLRT----HAI 132 Allomeiothermus...
WP_012693495  81 -------sD-------------ESDNGVLKRTGFDREPLYPAg-fEFDPAAREARLRRIWDPFDAQVRSEL------PGT 133 Deinococcus des...
Q9RUI9        80 -------dD-------------SEDNGVLKQMTFDRQPLYPAg-fALTPPAREARLRRLWDSFDAQVTREL------EGA 132 Deinococcus rad...
WP_011530748  81 -------nD-------------HTDNGVLKLTDFARRPLYPAg-fTLTPERREGRLRRIWDAFDAQVGVEL------EGV 133 Deinococcus geo...
WP_012106178  69 LPLp----P-------------KDPDGIIKVRTIDGKQVYLPgqiP-DLNLIHQMMLKWYFPYHQRIDELIDR----HPV 126 Methanoregula b...
WP_015286524  71 LPLp----P-------------RDPDGIIKIRTVDGRLVYREgmvP-DLPLIHKLLMAWYFPYHQKIDELIDG----CDV 128 Methanoregula f...
WP_012064822  74 RDLp----P-------------SNPDGVVKTMTVDGKQIWVQa-sGLSQREIQLLIQQYHGPYHERLQTASKN----KNV 131 Alkaliphilus me...
WP_013488884  75 DDLp----P-------------LNPDGVIKTRTVNGDPVWSSv--rLLEEDIAVLLEKYYYPYHEKLKKASQN----PRV 131 Evansella cellu...
WP_012215386  70 QDMp----P-------------DNPDGLIKSMTCYEKPIYIKg-kEPNESLRDLLVEFYYMPYHRALQKSFSE----LDL 127 Nitrosopumilus ...

2Q7S_A       166 VWHLNLHSXPNNAYErlkiQs----PRPLADFVL--GDRD---GT--------TCEPGLVDLVEREL---REKGYT---- 221 Cupriavidus pin...
WP_013159623 133 RLLVNGHSMQPTGPA----Igp-daGKPRPGICLmaGTDA----QgdpvashsSLPKRVAREVLGLAqrhFAPVLRgqp- 202 Allomeiothermus...
WP_012693495 134 RLMIVGHSMAPYGPA----Lgp-dtGTPRPALCLmpGTPAa-----------pTFPTELWEPLRRACqeaFSDAVAgsp- 196 Deinococcus des...
Q9RUI9       133 RLMIVGHSMAEFGPA----Lgp-drGEPRPALTLmlGTEQh-----------pTVPHQHWDALQAACaeaFAPALTgry- 195 Deinococcus rad...
WP_011530748 134 ALMIVGHSMASRGPA----Lgp-dtGKLRPALTLmlGTERa-----------pTFPPDRWEALQAACaeaFAPVLSgdl- 196 Deinococcus geo...
WP_012106178 127 RISFDCHSMLPYGSA----Eqa-daGRDRPLICL--GNYGdgqGRarpg-gitTCPAAWIRSLADEF---E-REFPgp-- 192 Methanoregula b...
WP_015286524 129 AIAFDCHSMLPWGSG----Eqk-daGKKRPLICL--GNNGdrmGRagkn-gitTCSHRWIRELAGEF---R-KEFClg-- 194 Methanoregula f...
WP_012064822 132 LMGIDCHTMLDIGPA----Vgg-nhWEERPLFCI--GNRGtkmGNqld--eptTAPRELLLQLQKSL---E-KEFRafmp 198 Alkaliphilus me...
WP_013488884 132 RLGVDCHSMLNIGPT----Tdy-aiWEKRPLFCI--GNRGsstGEyvs--epiTAPPELMHKFKQLL---E-TKFSpiig 198 Evansella cellu...
WP_012215386 128 QLCLDCHSMASVAPG----IspdgaNKKRPLFCL--SNQD---GK--------TCSDEMLELLADCI----SSSYSidr- 185 Nitrosopumilus ...

2Q7S_A       222 -------VARNDPYKGVQLIAQIG---RPAERRNSLQIEIRRPLY 256 Cupriavidus pinatubonensis JMP134
WP_013159623 203 ----teaITLGEPWKSDQISQRYSdpaRP-RPVWGFGLEFNRALY 242 Allomeiothermus silvanus
WP_012693495 197 ----dprVTIGEPWSTDTLSLTHQ---RH-SGVPAFGIEINAGLF 233 Deinococcus deserti
Q9RUI9       196 -----trVAVGDPWTTDTLSAAHQ---AR-TGIPAFGLEINVALY 231 Deinococcus radiodurans
WP_011530748 197 -----trVAVGDPWTTDPLSARWH---AR-TGVPAFGLEINVALY 232 Deinococcus geothermalis
WP_012106178 193 -----gnVAINTPFSGGFISNAHY---W-RKGIPWIQIEVNRALY 228 Methanoregula boonei
WP_015286524 195 -----qeVAINNPFSGGFISNAHY---W-RKGIPWIQIEINRALY 230 Methanoregula formicica
WP_012064822 199 ketqqplVTLNTPFSGGYITYYHG---N-NSDIPWIQLEINRKLY 239 Alkaliphilus metalliredigens
WP_013488884 199 dkfdlpiVTMNEPFSGGYITRAHG---N-VGYIPWIQLEINRELY 239 Evansella cellulosilytica
WP_012215386 186 -----keISLNDPFHGGHITKTYG-----NNPLPWIQIEMNRSLY 220 Nitrosopumilus maritimus
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