6J4X


Conserved Protein Domain Family
RNA_pol_Rpb1_7
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pfam04990: RNA_pol_Rpb1_7 
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RNA polymerase Rpb1, domain 7
RNA polymerases catalyze the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). This domain, domain 7, represents a mobile module of the RNA polymerase. Domain 7 forms a substantial interaction with the lobe domain of Rpb2 (pfam04561).
Links
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Statistics
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PSSM-Id: 398588
Aligned: 72 rows
Threshold Bit Score: 122.284
Threshold Setting Gi: 74833040
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6J4X_A   1143 TTLKNVTSATEIYYDPDPTSTVIEEDFDTVEA--YFS-IPDEKVee---tiDKQSPWLLRLELDRARMLDKQLT-MNQVA 1215 Komagataella phaf...
CBN73767 1204 vTLGDITTSTQIYYDPDPRSTVVDEDVELLEG--HFD-IQEEEEddk--dtDRARPWLLRMELNREAVFDKRLD-VVEIA 1277 Ectocarpus silicu...
Q584K3   1160 CTLESITRRIQFIYDPDPRHTVVEADRDILEL--EWNvMDESDAelriqevVAGSPWVVRLELDVDMVTDKALD-MKDVK 1236 Trypanosoma brucei
CAM70645 1137 CTLANITTTVQIIYDPDPRNTVVAEDEEMIRW--EQAvMNEEDEepd--aeqPPSPFIARLILDNDLFNDKRLN-MKDVK 1211 Leishmania infant...
EEA07210 1193 TTLENITTMAHILYDPKFDETIVEADKQWVSD--YYE-FP-DDVdi----kSRLGTWLLRIQLNSKLVTDKKLS-MKEIG 1263 Cryptosporidium m...
Q4N0F9   1156 TNFEKIVLSYTVVYDPVVDRTIIEEDYEWVRD--YYE-FPDEEM-------GTLGQFVLRIVLNSKIMTDKRLT-MKEVG 1224 Theileria parva
EDO05418 1159 TTLDKVVALSQVIYDPNVSQTIVPKDYAWVRE--YYE-FPDEDM-------NRLGPWVLRIQLSNKVMTDKRLT-MKEIV 1227 Babesia bovis
EEC44959 1098 TVLGDVVKKTEIYYDPDVKNTVVTKDREFVKE--FYD-FTDKTDdd----lRRMSPWVLRVELDKPLLYVKKIK-MEEIA 1169 Phaeodactylum tri...
EAY19064 1161 aSFKKFVIKAEIYYDPNPEETIIEPDTKWINTriRYGgVEDREL-------QDLAPWVLRFEINREEMIASNIEsISDIV 1233 Trichomonas vagin...
EGD77094 1174 TPLSAVVKKSSICFDPDERNTIIQEDLEFLQD--YFD-DPDYHP-------EDLSPWVLRLELDSVQMTLRDVS-CDMIE 1242 Salpingoeca rosetta

6J4X_A   1216 DKI---------SEVFSDD-LFVMWSEDNAD-KLIIRCRVIR---------DPKA---MDEELE--AEED---------- 1260 Komagataella phaf...
CBN73767 1278 KRV---------VAYFDGG-LHVIRSDQNSE-KLVLRIRVLD---------DVPDkieAEPEAEdmAEADd--------- 1328 Ectocarpus silicu...
Q584K3   1237 QAIlrvdesyiiETGMANN----------VR-QRTIRMRSRY---------------------NegADSI---------- 1274 Trypanosoma brucei
CAM70645 1212 SAIrqvddtymvQANMEND-----------G-QRIVRLRPRK---------------------CtgADSV---------- 1248 Leishmania infant...
EEA07210 1264 DKI---------LMEFSNDeLDCIWTDDNSD-ELVLRLRIKNle------------ptNSGTQDtvMNSEfqiddghyqp 1321 Cryptosporidium m...
Q4N0F9   1225 EII---------YSEFSNGeIDAIYTDDNSE-LLVMRIRVKYg---------------GEGDNSgpSDTEa--------- 1270 Theileria parva
EDO05418 1228 DRI---------YQEFSNDeIDCIHTDDNND-ELVLRIRVKYs--------------nMDVDQQnmGENEg--------- 1274 Babesia bovis
EEC44959 1170 KEI---------GEEYGAD-LNVEVTDDNAD-EMVVRIRIVNdtpfnsgqtDEGGn-lMDDQPEvgQEDD---------- 1227 Phaeodactylum tri...
EAY19064 1234 QKI---------KGMYGDK-FFVIGDDD----ARIIRMQAR-----------------LKDEQAefAMDV---------- 1272 Trichomonas vagin...
EGD77094 1243 EKI----------ESYLEStVKCVYTTNAAAkQKVMRIRLTKve-------------eNEEGMEdfMSAD---------- 1289 Salpingoeca rosetta

6J4X_A   1261 ---------QMLKRIEAHMLDLIALR 1277 Komagataella phaffii GS115
CBN73767 1329 --------vAMLKHLEKNLLRlqlsg 1346 Ectocarpus siliculosus
Q584K3   1275 ---------PKLKREIPALLARVHLR 1291 Trypanosoma brucei
CAM70645 1249 ---------PALTKAVAQLLQSVHLR 1265 Leishmania infantum JPCM5
EEA07210 1322 ptppvveehKFLEKLMTECLSQITLR 1347 Cryptosporidium muris RN66
Q4N0F9   1271 ---------DFLNKFMTDVLCGIKLR 1287 Theileria parva
EDO05418 1275 ---------EFLQRFMSQVLVNVKLR 1291 Babesia bovis
EEC44959 1228 ---------IFLKRLEKSMLSSLKLR 1244 Phaeodactylum tricornutum CCAP 1055/1
EAY19064 1273 ---------KFLRETEQQMYKSFTLK 1289 Trichomonas vaginalis G3
EGD77094 1290 ---------RLLRLVEERLLKNLHLK 1306 Salpingoeca rosetta
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