Conserved Protein Domain Family
TM_HPP
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pfam04982: TM_HPP (This model is not part of the current CDD release)
HPP, transmembrane region
This entry represents the C-terminal transmembrane region of At3g47980 from Arabidopsis thaliana, which is involved in nitrite transport and similar integral transmembrane proteins. The most conserved region of the alignment is a motif HPP. It is predicted to show five helices.
Links
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Statistics
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PSSM-Id: 516548
Aligned: 216 rows
Threshold Bit Score: 42.0912
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_003710406  46 HAIGNLVYIFWAFLGVFTSILLIL---AVNHHVgefRAHNAPMIVASFGAAAVLEFYSIEAPLAQPRNAILGQVISALVG 122
XP_020871805  87 ATALLMSDVIWPAAGAFAAMAILG---RMDQMLyp---kgISMSVAPLGAVSAILFITPSAPAARKYNMFLAQIGCAAIG 160
Q012T7        73 VGARPFSDAVFGFAFCAATFAALG---VCDDVVkrvVGAATPFMIGAWGSLGVLAFGTLDAPPLRLWNVVAATAASATVS 149 Ostreococcus tauri
XP_002507972  69 VQKRPTSDIFWAFLMCFVTLATLG---LVDRYMh--VTHGLPFMSGAWGTISVLAFGTVENPAARLYNCVTATVASAFIV 143
BAJ01691      18 IYMNKLIPHLIAGLGASIAIGLLS---FLDTNL-----TNVVLIMAPFGATAVLVFGLPDSPLAQPKNVVFGHLITAFIG 89 
Q4FMT8         1 MIHITKEKLLKASIAGVLSTITIGfltLLTYKTt-----MGLFLAASFGSSMVLLYGFPESPFAQPKNIFFGHFLTALIG 75  Candidatus Pela...
Q8EH38         4 INPQNLKMALLAGCGAMLCISSLA---ALEQLT-----PQTIWLMAPFGATMVLLFALPESPLAQPRNILCGHLLTSLVG 75  Shewanella onei...
WP_023787011  20 VAALPWRQAALAGIGGALAIGLLA---VMNATE------TLPLLIPPFGASCVLVFGVSASPFARPRNVIGGHVISAAVG 90  Hyphomicrobium ...
WP_010080107  21 APRLPWHVVLAASIAGALTIATLS---LGEDLA------SVPLLVGAFGSSCVLVFLVPHGPHSHPANVLVGHVVSAACG 91  Micrococcus luteus
WP_038546366  12 QPRMPLGGLVLSTVAVVVAVALLS---GLSELS------GHPFFMASLGATCVLLFILPAAPLSQPLNIVGGYLLSTTVA 82  Corynebacterium...

XP_003710406 123 TIVATIFGgperllqstsddptlgfrslvyRWAGGALACAAATACMALTGTVHPPAGATALMAVVDDRIVE-LGWWYIPI 201
XP_020871805 161 VVAFSFFGp---------------------GWLARSVALAASIAFMVITRANHPPAASLPL-MFIDGAKFHhLNFWYALF 218
Q012T7       150 ILCVNALGp---------------------TWLARSLSLSLSLVIMMRLGALHPPAGAVAL-AAMD-AHYYnLQWLYVVY 206 Ostreococcus tauri
XP_002507972 144 ATMVMLFGs---------------------CWWTRALSVATALGFMMWTGSVHPPGAAAIM-GCMDQAAFQqLGYWYVLY 201
BAJ01691      90 LFFVHFIEv---------------------SPLTLGLATGIGVSAMLMSKTTHPPAGANPLLIMLSGQS---LGWFFLVT 145
Q4FMT8        76 ILFINYVDl--------------------pIFINIALAVGFGIFFMIVLDVVHPPAGGNPIMVIIGG-----VSFEYLIN 130 Candidatus Pela...
Q8EH38        76 LIILNTLGv---------------------SPLTLGLAVGLGIAVMMLTHTVHPPAGANPLVVMLTAQ-----HWDFLYM 129 Shewanella onei...
WP_023787011  91 LVAVSAFGg---------------------GVLGVAAGVGLAIAAMILSDTVHPPAGANPIVVALSGA-----GWPFLIA 144 Hyphomicrobium ...
WP_010080107  92 IAVISVLPl---------------------TWYSLAAGMGLAMAVMAGLRVIHAPAGATALTVMLSNA-----DWDYLVT 145 Micrococcus luteus
WP_038546366  83 VVLFSFLPs---------------------EWWSLALATGAAAMLMTGLRILHPPAATMPMLVTTGGE-----SWHYLLE 136 Corynebacterium...

XP_003710406 202 -MLLGCALMLGVALLVNN-VQ----RRFP 224
XP_020871805 219 pGAAACVILCLLQSIVCY-Lk---eNMKF 243
Q012T7       207 pALLGSCLILVMSRACQTl-----kRRYE 230 Ostreococcus tauri
XP_002507972 202 pVLFGSLFVLFMGHLTHK-L------KHR 223
BAJ01691     146 pVLIGALVIVLIGKFMQE-LQk----KFN 169
Q4FMT8       131 pIIFGCLIILIFGIILNKfi---lkKNYP 156 Candidatus Pelagibacter ubique HTCC1062
Q8EH38       130 pVASGVALILAFGWLYHN-LLc--sRQYP 155 Shewanella oneidensis
WP_023787011 145 pVLIGAATIVVCGWIYNR-MRt---GASV 169 Hyphomicrobium nitrativorans
WP_010080107 146 pVLTGALVLTACALLYRR-LMwrviGPPG 173 Micrococcus luteus
WP_038546366 137 pVFVGALVVAVLGILYRTvVGd--rIWGR 163 Corynebacterium glyciniphilum
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