Conserved Protein Domain Family
HupE_UreJ

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pfam04955: HupE_UreJ 
HupE / UreJ protein
This family of proteins are hydrogenase / urease accessory proteins. The alignment contains many conserved histidines that are likely to be involved in nickel binding. The members usually have five membrane-spanning regions.
Statistics
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PSSM-Id: 398558
Aligned: 46 rows
Threshold Bit Score: 91.8899
Threshold Setting Gi: 123759086
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q117C3         35 S-----TTELAMAHHPMGGkipANfw---eGLISGMGHPIIGIDHLSFVVGVGLIAAGM--SNSILVLVSFLATAMLGTG 104 Trichodesmium ...
WP_011761352   16 Tm----VAWPAAAHDIYA----NG------GFLAGAIHPFLGLDHLLTIFAASLIGMQLggRARVSVPLAFLLFFIFGDI 81  Shewanella ama...
jgi:Sama_3272   8 Wcl--lFSAGASAHEVAL----GG------GFGAGFSHPVLGLDHLLAMLSVGMVSTRLgrHAIWQVPLAFLCFMSLGAV 75  Shewanella ama...
WP_011864133    9 Lll--aWTTPVFAHGITH----GA------GFMTGFNHPVLGFDHLLAMLSVGLLSTQLggRAIWTVPLAFMAFMLVGGI 76  Shewanella loi...
O66897          6 Pfv--gLASFAFAHPGHFHgv--------nPFNSGLIHPLTGLDHLSVMVAVGLLGSYYagKKAFLPALTFVSFMTLGSI 75  Aquifex aeolicus
P73671         69 L-----TFPRLLAHHPFGGhtpSNfl---eGFLSGLGHPVIGLDHLAFVIAIGLIAAGL--RYGWLMPLIFVATAITGTG 138 Synechocystis ...
Q31NG6         28 Lll--sIASPAFAHHAMGG---QTptsifeGLLSGLAHPIIGVDHFAFVIAVGLLASVT--RQGFLSIFAFVIAALIGTG 100 Synechococcus ...
WP_011749367    7 AalaalMGSPVLAHTGVGE---TS------GFTAGLSHPIFGPDHLLAMLAVGLWSGFVlpHRFWLGAATFMGAMAVGAL 77  Paracoccus
Q3J0L6          9 Vls--aAASPALAHTGHGD---AS------GFAHGLLHPILGPDHLLAMLGVGIWSGIAlpRHLWGGAATFLAAMTVGAA 77  Rhodobacter sp...
Q6W1Q7         12 Ita--sLPGQALAHSGNDH---VH------GVASGLLHPFSGVDHLLAMIAVGLIAGRLggSALFRLPLAFVSAMVAGAA 80  Sinorhizobium ...
Q117C3        105 IHLLSIDLPLTEIAIAISVVALGAMLAFKQKLNT----PLVIIFAAISGIFHGYAYGEAIIGSEMTPLlaYLIGFTAMQL 180 Trichodesmium ...
WP_011761352   82 IGLLQVPMPWVEPGIALSGILLGLALLMGRDVPL----SFAQALVGIFALFHGHAHGTEIPMGANPVW--YTLGISVGTV 155 Shewanella ama...
jgi:Sama_3272  76 LGITDIALPLVEAGIALSVMLLGLAIAFNRALPL----WPAMLAVAVFGIFHGHAHGMEMPTLASPWL--YGLGFILGTA 149 Shewanella ama...
WP_011864133   77 LGLYGVALPWVELGIALSVLLLGLAIALGRHIPL----LLAMGFVGLFAIFHGHAHGAEMPALASPVL--YALGFLTGTA 150 Shewanella loi...
O66897         76 LGLLGVSVPFVESGIILSVALMGILL-FAKDLKL----SYVLPLIGIFGILHGVAHGYEAPQTLHPVY--YVLGFVLSTA 148 Aquifex aeolicus
P73671        139 LHLIGANLPQPELVIAGSVLLFGIFLALGRPLPS----PLVMGLAAVAGMFHGYAYGEAIVGAQMNPVaaYLLGFSFIQL 214 Synechocystis ...
Q31NG6        101 LHLANLNLPGAELLISGSILIFGCLLARKKALPV----AAIAGLAAIAGLFHGYAYGEAIIGAGMPPLfaYLVGFTLTQL 176 Synechococcus ...
WP_011749367   78 ISWAGIPIPMVESWIVLSVVAFGLLTAFSRRGQSdqitFASLAAIALFAICHGHAHATEAHGNAAA----YMIGFLISTA 153 Paracoccus
Q3J0L6         78 LSWAGVGIPMVETWIVGSVVLAGLLVATARAGQArlvtGLSLGAIATFAACHGHAHATEATGAIGA----YLAGFLIATA 153 Rhodobacter sp...
Q6W1Q7         81 YVLTGVTVPLVEAAVITSVILLGAALIANANIPA----TLAITGAATFGFFHGFAHGTEGPA-AAPLG--HILGFIGGTV 153 Sinorhizobium ...
Q117C3        181 FIALFAMKSAELVSSYWQNqff--rlMSFLGLFISTIG--L 217 Trichodesmium erythraeum IMS101
WP_011761352  156 AIMLFGGAVAWYLSLIDQPkp----lLRGLGGIITSLG--L 190 Shewanella amazonensis
jgi:Sama_3272 150 TIHLIGVFTGLLLAMKERRyp----lTRITGAGIAAMGtlF 186 Shewanella amazonensis SB2B
WP_011864133  151 VIHLLGVALGIIMQQLSHKlp----lLRLSGGVIALVGgyL 187 Shewanella loihica
O66897        149 ALHFTGLLFGKALKEKl---------VRVSGLLLLALAflL 180 Aquifex aeolicus
P73671        215 AIAMGVYALAKGWYETKETll----nLRFIGFLLTGVG--L 249 Synechocystis sp. PCC 6803
Q31NG6        177 VIAISAWAVGCTLIRQQSAtesltapLKTSGLVLVGIGlaf 217 Synechococcus elongatus PCC 7942
WP_011749367  154 ALHIVGIFIARTISNATAArm----vQAATGTGIAVAGlaL 190 Paracoccus
Q3J0L6        154 GLHAAGIGVALATARGGRIl------QGALGAALAGSGllL 188 Rhodobacter sphaeroides 2.4.1
Q6W1Q7        154 ILHITGMTVWHALARRGTGpm---paHRIIGTGIIGAGigL 191 Sinorhizobium fredii NGR234
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