Conserved Protein Domain Family
YHS

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pfam04945: YHS 
YHS domain
This short presumed domain is about 50 amino acid residues long. It often contains two cysteines that may be functionally important. This domain is found in copper transporting ATPases, some phenol hydroxylases and in a set of uncharacterised membrane proteins. This domain is named after three of the most conserved amino acids it contains. The domain may be metal binding, possibly copper ions. This domain is duplicated in some copper transporting ATPases.
Statistics
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PSSM-Id: 487440
Aligned: 10 rows
Threshold Bit Score: 51.6116
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9ZC53            408 VVDPVDKSHLtNQkSEYKYSYGGKTYFFSSEANYNRFRDHPEQFVTPV 455 Yersinia pestis
Q9HJ30              2 ATDPVCGMYV-PEtSDLYVDRDGTRYYFCSKGCMDKFLEPEKEGKNLA 48  Thermoplasma acidophilum
zhongguo:Q91_1781  16 HKDPVCGMDVsKD-TQYQTEYKGQWYGFCCEGCLIKFNKDQDMYLSGq 62 
O87082            403 IGSHWDRFHL----KPEQLVYKGRLYTFDSDVSKWIFELDPERYAGHT 446 Xanthobacter autotrophicus Py2
Q97YT0            197 IQAPANGKYL----RIYLKEYKGKMYTFDSPACLWIFEQEPERYAGRR 240 Saccharolobus solfataricus
Q9KLU4             38 VAYFTEGKPV-KGaAQFKTEYQGAEWLFASQQNLDAFLADPEKYAPQY 84  Vibrio cholerae
Q9CNI0            415 VIDPVDHSQLkNTrTEHKYSYEGKTYFFATEKNLHLFRDAPENYLNAE 462 Pasteurella multocida
Q9WYF0              3 VKDPVCGMKIeKEeAAEKIEYMGKEYYFCSQECAEKFKDNPEQYAHQK 50  Thermotoga maritima
Q0K3T5            407 fSEPDDPTQT----CYRESSYHGMKFHFCSDGCKDIFDDEPAKYAQAW 450 Cupriavidus necator H16
Q9HJ29              1 MIDPVCGMKVdKN-AKFKSTYNGKEYYFCSEHCKVEFDRNPIKY--TR 45  Thermoplasma acidophilum
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