2HHP,4LT6


Conserved Protein Domain Family
PAP_RNA-bind

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pfam04926: PAP_RNA-bind 
Poly(A) polymerase predicted RNA binding domain
Based on its similarity structurally to the RNA recognition motif this domain is thought to be RNA binding.
Statistics
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PSSM-Id: 398540
Aligned: 106 rows
Threshold Bit Score: 85.7989
Threshold Setting Gi: 378756776
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2HHP_A       353 DFFFRYKFYLEITAYTRgSDEQHLKWSGLVESKVRLLVM--------KLEVLAGIKIAHPFTKPF--ESSYCCPTEDDYE 422
EDQ85233     383 RFFDEYQYFVRVVASAA-TESDRTEFEGLVESTVRHLVL--------NLQYTDNVAYAMAYPKAY--HEDPVADKDGTEA 451 Monosiga brevic...
Q17AA5       434 SFFFKYRHFIVLLVTSN-NADDHLEWCGLVESKIRYLIL--------NLERNQHINLAHVNPKCF--EQHEQNQTERQRE 502 yellow fever mo...
Q9N6D7       374 SFFYRYRHFIVLLVNSQ-TADDHLEWCGLVESKVRLLIG--------NLERNPHIALAHVNPKCF--EFKKGQSANNSQN 442 fruit fly
XP_004077012 366 SFFQKYKHYIVLTASAS-TEENHLEWVGLVESKIRVLVG--------NLERNEYITLAHVNPQSF--PGSKENRSEND-- 432 Japanese medaka
OWR49559     377 NFFSRYKHFIVLLASSA-NTLDQLPWCGLVESKIRHLIT--------TLERNQHITIAHVNPECY--NSVPLNTNNGHPL 445 Danaus plexippu...
Q4DA83       371 KFFGEHKYYLHVLVSCT-DAEAYQGYVDAVESRIRFLWAgtaesrgyALENIRHVRI-RLNPRRY--EAPEEVETRARLL 446 Trypanosoma cruzi
XP_001464305 374 PFFGKFQHYLQIKVSCS-DAEHYQAYADGVESRIRILWAgnassrghTLEDYRQLRL-HLNPRRF--EDPEEVQLRTRLT 449 Leishmania infa...
XP_001563421 374 PFFGKFRHYLHIKVSCS-DAEHYQAYADGVESRIRILWAgnassrghTLEDYRQLRL-HLNPRRF--EDPEEVQLRTRLA 449 Leishmania braz...
4LT6_A       371 NFFQKYRHYIVLTASAS-TEENHLEWVGLVESKIRVLVG--------NLERNEFITLAHVNPQSFpgNKEHHKDNN---- 437
2HHP_A       423 M-IQD---KYGSHKTETalnalklvTDENKEEESIKDA----------------PKAYLSTMYIGLDFNI-ENk------ 475
EDQ85233     452 T-----------------------------------------------------TGPWRTAWYLALEFGI-KQegriepa 477 Monosiga brevic...
Q17AA5       503 SdGSR-------------------------------------------------ASTLCSLWFIGLEFER-SEn------ 526 yellow fever mo...
Q9N6D7       443 NsGNEddlKQSQGNQSAv-------T----------------------------SAPFCSMWFIGLEFER-SEn------ 480 fruit fly
XP_004077012 433 ---------------------------------------------------------FVCMWFIGIIFKK-VEna----e 450 Japanese medaka
OWR49559     446 AlPPGtpvQTEEHGAAEv--------KNDKG-----EI----------------VANVCSMWFIGLVFDK-TN------- 488 Danaus plexippu...
Q4DA83       447 KkTSRssgGGNGSMEVSs--------HQTSGAVDDSSS----------------PKIFSCHYFIGMSVDP-KAt------ 495 Trypanosoma cruzi
XP_001464305 450 SkATGaaaASSHTRGSVg--------SRTSGQLGDGGSslvgsinakdssapsgPTWFTAHYFIGMAVDT-KVs------ 514 Leishmania infa...
XP_001563421 450 SkASGaaaA-NHTRGSVg--------SRTTGQLSDSGStlrgsppmkdstvslgQTWLTANYFIGMTVDT-KVs------ 513 Leishmania braz...
4LT6_A       438 ---------------------------------------------------------YVSMWFLGIIFRRvENae----- 455
2HHP_A       476 kEKVDIHIPCTEFV-NLC-RSFN--Ed-YgDHKVF---NLALRFVKGYDLPDEVFDENEKRP 529
EDQ85233     478 pSKLDLQGPLVAFYgRLRdRTVT--MsrY-DETTM---NVDVQAMKQSKLPGYLYPGGVNPH 533 Monosiga brevicollis MX1
Q17AA5       527 -LNVDLTESIQSFTdSVH-KHAV--HikL-LKDGM---KIEARHVRRKQLSQYLDPNLLKRE 580 yellow fever mosquito
Q9N6D7       481 -LNVDLTESIQNFTeHVM-MHGV--NikM-LKEGM---TIDARHVKRKQLSLYLDSDFLKRE 534 fruit fly
XP_004077012 451 sVNIDLTYDIQSFTdTVY-RQAN--NinM-LKDGM---KIEATHVKKKQLHQYLPPELVQRK 505 Japanese medaka
OWR49559     489 -VNVDLTYDISSFTkAVH-YQAE--NtnV-LREGM---TIEARHVRRKQLHQYL-SPSLLRR 541 Danaus plexippus plexippus
Q4DA83       496 sGKIYLAPSIRAFH-GIV-RQLR--Q--Y-KEGITrlpVITVEDIS--KIPAFVKSAAGFKE 548 Trypanosoma cruzi
XP_001464305 515 sAKIDLAPAIRTFH-TVV-RELR--Q--Y-REGVTrlpVITVVDMA--RIPTFVKEAAGHVE 567 Leishmania infantum JPCM5
XP_001563421 514 sAKIDLAPAIRTFH-AVV-RELR--Q--Y-REGVTrlpVITVVDMT--RIPTFVKEAAGYVE 566 Leishmania braziliensis MHOM/BR/7...
4LT6_A       456 sVNIDLTYDIQSFT-DTVyRQANniN--M-LKEGM---KIEATHVKKKQLHHYLPAEILQKK 510
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