6QNX


Conserved Protein Domain Family
Rad21_Rec8_N

?
pfam04825: Rad21_Rec8_N 
N-terminus of Rad21 / Rec8 like protein
This family represents a conserved N-terminal region found in eukaryotic cohesins of the Rad21, Rec8 and Scc1 families. Members of this family mediate sister chromatid cohesion during mitosis and meiosis, as part of the cohesin complex. Cohesion is necessary for homologous recombination (including double-strand break repair) and correct chromatid segregation. These proteins may also be involved in chromosome condensation. Dissociation at the metaphase to anaphase transition causes loss of cohesion and chromatid segregation.
Statistics
?
PSSM-Id: 398479
Aligned: 107 rows
Threshold Bit Score: 59.1018
Threshold Setting Gi: 268560930
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
6QNX_B         1 MFYAhfv-lskRGPLAKIWLAAHWd------kKLTKAHVFECNLESSVESIIS-PKVKMALRTSGHLLLGVVRIYHRKAK 72 
EFQ32753       1 MFYSheilnsrQFGVATIWVVATIgprgggkrKISRKAIEEVDIRKACEKIIE-PGAPISLRLQSNLLFGVSRVYSSKCN 79  Colletotrichum ...
ERS99517       1 MFYSteilcdkRYALSTVWRAGNTaiga-rttGIRRNAVLEVSVKQTCGTIKDpPGAPIALRLQGTLLYGTARIYQEQCR 79  Sporothrix sche...
EQB58408       1 MFYSheilnnkQYGVATIWHIANFgqsn-slkRVTRKVIDEVKISKACAKFMD-PGPPIALRTQSKLLFGTVRVFERQCY 78  Colletotrichum ...
EGX92359       1 MFYSnqiltstQYGVSTIWLIATVgks--nqkRVTKRAIQDVNVPRACDKILD-PGAPLALRLQGNLLYGVSRVFADQCG 77  Cordyceps milit...
KNA99462       1 MFYSheilsntQYGVATIWLVATVgks--nqkRLTRKAIQQVNVPKACETIIN-PGAPLALRLQGNLLYGVSRVYAQQCR 77  Fusarium oxyspo...
XP_007798570   1 MFYSheiltsrQYGVATIWLVATIgnks-sakKVTRKAIQEVDVEKACGKILD-PGAPIALRLQGNLLYGVSRVYRDQCT 78  Eutypa lata UCREL1
Q7SGX9         1 MFYSheiltnqQYGVATVWLVSTFglrs-snrKISRKAIQEVNVRKACETILQ-PGAPIALRLQGSLLYGVSRVFSQQCS 78  Neurospora crassa
KLU83324       1 MFYSheiltshKHGVATVWVLATLgqnc-gsrRISRKAIQEVDVPKACMTIDNpPGAPIALRLQASLLYGVSRAYSQQYD 79  Magnaporthiopsi...
XP_003721082   1 MFYSheiltsqKHGVATVWVLATLdrsc-asrKVSRKAIQEVNVPKACVTIDEpPGAPIALRLQASLLYGVSRVYQQQCH 79  Pyricularia ory...
6QNX_B        73 YLLADCNEAFIKIKMAFRp-gV----VDLPEeNREA 103
EFQ32753      80 YMLNDAEKVQTLMKTFFRlia--nneTVPNA-GRAR 112 Colletotrichum graminicola M1.001
ERS99517      80 YVLNDSERAQRAMAKLHNgfl--ddkLDKNA-GRAK 112 Sporothrix schenckii ATCC 58251
EQB58408      79 YTLHDAEKVRQLMKDLFAsid---naIDMNA-GKTR 110 Colletotrichum gloeosporioides Cg-14
EGX92359      78 YLLSDTEKTQSDMMTFFRaik--gshLDLPD-TRTK 110 Cordyceps militaris CM01
KNA99462      78 YMLSDAEKTQSDMMTFFRvmd--tseTDPNA-GKSK 110 Fusarium oxysporum f. sp. lycopersici 4287
XP_007798570  79 YMLTDTQKIQTHLLTLFNkfg--dnhLDPEA-GHTR 111 Eutypa lata UCREL1
Q7SGX9        79 YVLTDAEKIHMHMRCFYNvlgGtenaLDPQA-GKAK 113 Neurospora crassa
KLU83324      80 YLLSDAEKARLGMSILFKnles-sdtLDPKA-GKAK 113 Magnaporthiopsis poae ATCC 64411
XP_003721082  80 YVLGDAEKFRISMRGLMRvld--sgtLDPNA-GRAK 112 Pyricularia oryzae 70-15
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap