3EH2


Conserved Protein Domain Family
Sec23_helical

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pfam04815: Sec23_helical 
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Sec23/Sec24 helical domain
COPII-coated vesicles carry proteins from the endoplasmic reticulum to the Golgi complex. This vesicular transport can be reconstituted by using three cytosolic components containing five proteins: the small GTPase Sar1p, the Sec23p/24p complex, and the Sec13p/Sec31p complex. This domain is composed of five alpha helices.
Statistics
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PSSM-Id: 398471
Aligned: 339 rows
Threshold Bit Score: 46.7301
Threshold Setting Gi: 302769476
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3EH2_C        515 ETDTLINYMAKFAYRGVLnSPVKAVRDTLITQCAQILACYRKNCAspsSAGQLILPECMKLLPVYLNCVLKSDVLQPgAE 594  human
ELU41643      578 DLEC------KEALQMMSqRSLTEIRDSISEKCAALLLAYRRNCAastSPTQLILPEAFKTLPVYVLGLLKSRPLKGs-N 650  Rhizoctonia s...
EPS99566      576 DMDVVVCHLLREGIHKMRtQKIAKIQEQLTDKCAAILLGYRKWCAasaAASQLIIPEAFRALPLYTLAIMKSRPLKAq-N 654  Fomitopsis pi...
XP_007393301  572 DTDAVVTAMIREAVSKLSsQKISYIHEELTERSASILLGYRKHCAaatAPSQLIIPEAFRALPVYTLAMMKIRALKAr-S 650  Phanerochaete...
XP_007856464  566 DLDTTVTFLTRKAVSSIGsQKMSLIRDDLSESCASVLLGYRNKCAaatRPTQLIIPETFKALPIYTLAVLKSKPLKAr-S 644  Moniliophthor...
XP_007332631  564 DSSTILCRFAREAIVNMSkQKLSTTRDELTESCSAIFLGYRNKCTpasRVTQLIIPEAFRSFPAHLLALLKCKALKGr-Y 642  Agaricus bisp...
XP_001881319  561 DMEALVCHLAREAMSQLTsQKMSTVREDLTEKCSSLLLGYRDQCAagtRATQLILPEAFKALPAFILALQKSKPLKAr-Q 639  Laccaria bico...
EGO03690      569 DMDTVVCHLARDSIYNLSfRRMSHIREELTEKCSSLLLGYRRNCAastAPSQLIIPEAFRALPVYALAISKTKPLKGr-N 647  Serpula lacry...
CCA67291      621 DYEGVVAAFAKTAIMQMIkRPLRDIRDSLTAQCAELLLHYRRYCAassIASQLILPEGFTLLPVYVNCILKSRPLKg-TP 699  Serendipita i...
GAA99536      829 DVDTTLAYVAKECVFNAAtKALRDIREQLTDTCVKILLAYRKHCAsstSPGQLILPESFKLLPVYTMALTKSKAIKGg-A 907  Mixia osmunda...
3EH2_C        595 VTtDDRAYVRQLVTSMDVTETNV 617  human
ELU41643      651 VItDVRNYHAERLISISTSATMR 673  Rhizoctonia solani AG-1 IA
EPS99566      655 VVtDVRVYHAHKAMAMSARSTMQ 677  Fomitopsis pinicola FP-58527 SS1
XP_007393301  651 VSsDVRNYTAHRLMSISVRSTMH 673  Phanerochaete carnosa HHB-10118-sp
XP_007856464  645 VNsDVRNIYTHRLLSMSVQSTIR 667  Moniliophthora roreri MCA 2997
XP_007332631  643 VSsDIRNFTAHRILSSPPRDLLH 665  Agaricus bisporus var. burnettii JB137-S8
XP_001881319  640 VSsDVQNYEIHRIMSMSPRTTIH 662  Laccaria bicolor S238N-H82
EGO03690      648 VSaDVRNYYAQKLLSMGVRSTLQ 670  Serpula lacrymans var. lacrymans S7.3
CCA67291      700 VMsDVRNVHAHQLSSKTVAEAgd 722  Serendipita indica DSM 11827
GAA99536      908 VIsDVRAYYMRMLRSIGVTNLVE 930  Mixia osmundae IAM 14324
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