Conserved Protein Domain Family
LMP
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pfam04778: LMP 
LMP repeated region
This family consists of a repeated sequence element found in the LMP group of surface-located membrane proteins of Mycoplasma hominis. The the number of repeats in the protein affects the tendency of cells to spontaneously aggregate. Agglutination may be an important factor in colonisation. Non-agglutinating microorganisms might easily be distributed whereas aggregation might provide a better chance to avoid an antibody response since some of the epitopes may be buried.
Links
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Statistics
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PSSM-Id: 487334
Aligned: 7 rows
Threshold Bit Score: 126.891
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_012855441  494 KANTLLPQLNDNDSEIVKAKESLNAEITNANKAVnQNDNASMQSAKSSLDDKVTKIQNQLTEFNKDKDAKFKELEQTRKD 573  Metamycoplasm...
2_pfamImport    1 NAKEFKKLLIDNDQKIVDLKSNLDNEISKAEQSL-SKDKESMESANDLLNTKLIEYKEILNKFNQEKEAKFNELEQTRKN 79  
WP_012855702  132 vmrMLDNKLIDNDVDIQKTKKDLNSQIINALEIFnKNNIDEINNLNKSLTFKISEVEDILIKFKQSKEQEFEKLQKTRKL 211  Metamycoplasm...
3_pfamImport    1 NANQLLNKLVDSDKDIQKAKTELSQEIQSASQELnLNNPTSMQSAKESLDAKVTEITKKLETFNKDKDVKFKELEKTRKD 80  
WP_012855330  206 QANQLLPQLSDNDSEIAKAKKSLDAEIKNANQAVaSNNTASMQSAKSSLDAKVAEITKKLETFNKDKEAKFNELKQTRNQ 285  Metamycoplasm...
4_pfamImport    1 SANTLLAKLTDKDNTIQQAKTELEKEVQKANQAVaSNNTASMQSAKSSLDAKVTEITKKLETFNKDKDAKFKELEQTRKD 80  
1_pfamImport    1 NANTLSAKLTDKDNTIQQAKTELEKEVQKANQAIkSNNTASMQSAKSSLDAKVAEITKKLETFNKDKEAKFNELKQTRNQ 80  

WP_012855441  574 IDNFLTDDVKNNP----NYATLVKDLTNAKDDKKSVTKSSNKSEIIAANDELKQALDKAKVAKDQIDEANKSIKEQLSDS 649  Metamycoplasm...
2_pfamImport   80 IENFLTDEVKNNP----NYATLVKDLTNAKDAKKSVTNSSNKSDIIAANEALIQALADANKAKDQVDEANKSIKEQLNAL 155 
WP_012855702  212 VEEFLAKDVVKSD----YYANIVRNLNREVSRRGNVSISSNKSEIVAANINLNEVL---KQSKEFVENDMQKLRDSLisl 284  Metamycoplasm...
3_pfamImport   81 IDEFI-NTNKTNP----NYSTLISELTSKRDSKNSVTNSSNKSDIETANTELKQALAKANTDKAQADNLAKSTKEQLNNS 155 
WP_012855330  286 IQEFI-NTNKNNP----NYSELISQLTSKRDSKNSVTDSSNKSDIESANTELKQALAKANADKVQADNLAKSIKEQLNNS 360  Metamycoplasm...
4_pfamImport   81 IDEFI-KQIENDPqtkkNYQNIVKNLKDKKAEKNSITFSNNKKEIQDANKSLQDELNNAKITKKGITDFYNS-KKQLEDL 158 
1_pfamImport   81 IQEFI-NTNKNNP----NYSELISQLTSKRDSKNSVTDSSNKSDIESANTELKQALNTAKAKKSSIDNELRPLKNDLQSK 155 

WP_012855441  650 IT 651  Metamycoplasma hominis
2_pfamImport  156 ID 157 
WP_012855702  285 iv 286  Metamycoplasma hominis
3_pfamImport  156 IS 157 
WP_012855330  361 Vs 362  Metamycoplasma hominis
4_pfamImport  159 IK 160 
1_pfamImport  156 IE 157
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