3GWN,3GWL,4P2L


Conserved Protein Domain Family
Evr1_Alr

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pfam04777: Evr1_Alr 
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Erv1 / Alr family
Biogenesis of Fe/S clusters involves a number of essential mitochondrial proteins. Erv1p of Saccharomyces cerevisiae mitochondria is required for the maturation of Fe/S proteins in the cytosol. The ALR (augmenter of liver regeneration) represents a mammalian orthologue of yeast Erv1p. Both Erv1p and full-length ALR are located in the mitochondrial intermembrane an d it thought to operate downstream of the mitochondrial ABC transporter.
Statistics
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PSSM-Id: 398444
Aligned: 309 rows
Threshold Bit Score: 53.7815
Threshold Setting Gi: 209878312
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3GWN_A        12 AGWTFNHAVTFGYP-LNPT---SDDKRRY----KNYFISLGDVLPCR----LCRESYKKfITtgktALTNe--vLRNRHT 77  Acanthamoeba po...
XP_001121155 429 GLWTMFHMLTVNFAiLnk-----daEHEPrkilEAMYGYIQYFFGCA----DCSQHFVQ-MA----SKNKmf-eVSNIND 493 honey bee
XP_011135408 442 GLWTMFHTLTVNFAlEnrdesrdslQDDPaavlRAMHGYIENFFGCA----DCAAHFIE-MA----MRNGmf-dIRSRDE 511 Jerdon's jumpin...
EEB17630     406 GMWTLFHYMTVNALrDss-----qsNFNPlevlDAMLSYVTHFFGCT----ECSKHFQE-MS----QNKsmrtkVKTGDE 471 human body louse
Q9VD62       413 SLWTLFHYFTVLAAqMk--------VYPPssvtIGLYGLAKFFYDCK----DGSMYFVK-LA----KRMNia-kVRTHDE 474 fruit fly
EDW23799     420 SLWTLFHYLTSRRQaTv--------LLQPdralG--------IHACStlaaDCADHFLA-LA----ERKHie-rVTDYDA 477 Drosophila pers...
EKC26420     405 GMWTLFHTITVNSYlYgkd----saKFLYrdvlTAVAGYMKHFFGCS----YCSKHFTQ-MA----ATMDs--dVTSPKE 469 Pacific oyster
2_pfamImport   2 ALWTMFHTLIVQAHlYp--------PAEPkqplRAMRGYITHFFGCT----DCSQHFQS-MA----ETMEg--nVTDTTS 62 
XP_009020825 399 SLWVTIHTLLVSAHrNPRG---EnvQRVGmdilLAFRGYIEHFFRCI----ECRENFVK-YS----KNWLt--ePKNAS- 463 Helobdella robusta
Q20514       420 GLWTLAHTITVEAYkQEKH---NTAfKPVidvlEPFRAFIFHFLSCS----ECAQNFTK-EA----EKNQlh-lVTRPED 486 Caenorhabditis ...
3GWN_A        78 LTKW--------FYDVHNAVNNKLEvDYGlSYE---DV-VNKY 108 Acanthamoeba polyphaga mimivirus
XP_001121155 494 SILW--------LWSAHNEVNARLSg----DNTedpEYkKIQY 524 honey bee
XP_011135408 512 SILW--------LWRAHNEVNARLSg----DNTedpEHkKIQY 542 Jerdon's jumping ant
EEB17630     472 AVLW--------LWSAHNEVNKRLSk----DKSedpQFpKISF 502 human body louse
Q9VD62       475 EILW--------LWEAHNEVNEKLAg----DASgdpRFpKVQF 505 fruit fly
EDW23799     478 EILW--------LWEAHNEVNKRLAg----DTTedpKFpKIQF 508 Drosophila persimilis
EKC26420     470 VVLW--------LWRSHNKVNKRLHg----DASedpMHpKVLF 500 Pacific oyster
2_pfamImport  63 SILW--------LWKAHNSVNKRLHn----DPTedpKHpKLQF 93 
XP_009020825 464 ---WtakkasidIWRRHNLVNLNLH-KIS-PLTedpEFpKIQF 501 Helobdella robusta
Q20514       487 VYAW--------LWRVHNFVNKRLSg----SLTddpSFkKQQF 517 Caenorhabditis elegans
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