Conserved Protein Domain Family
Pex2_Pex12

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pfam04757: Pex2_Pex12 
Pex2 / Pex12 amino terminal region
This region is found at the N terminal of a number of known and predicted peroxins including Pex2, Pex10 and Pex12. This conserved region is usually associated with a C terminal ring finger (pfam00097) domain.
Statistics
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PSSM-Id: 398431
Aligned: 107 rows
Threshold Bit Score: 71.6473
Threshold Setting Gi: 124472526
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q54N40        23 QHQMMPSFKPALKYIFTV--L-S------------QRNPkfr--yiVNYYDECFYSLLLLLEYHYLKYYEGSFSENFYNL 85  Dictyostelium d...
Q4SN40        61 DSALEQLLWTQFSQCFQN--CrP------------GLLT--------PAEPELRALLQLLLWRFTLYSNSATVGQSLLSL 118 spotted green p...
Q28DK5        26 NKALEQLIWSQFNSCFQG--FkP------------GLLT--------RFEPEIKAFLCLFLWRYTIYTKNATVGQAILNM 83  tropical clawed...
P55098        26 NKALEQLVWSQFTQCFHG--FkP------------GLLA--------RFEPEVKAFLWLFLWRFTIYSKNATVGQSVLNI 83  house mouse
Q5ZM64        26 NKALEQLVWSQFTSCFHG--FkP------------GVLA--------HIEPEVKAFLWLLLWRFTIYSKNATVGQAILNI 83  chicken
XP_002026302  20 NKDIARLIRDNLLENLQA--IsP------------VLFI--------KFQPELDLLIQSAIWFGSVGKRCSTFGQQLLVL 77  Drosophila pers...
Q179Y9        18 DNEIVNILKEQVYSILRN--LpP------------GLLS--------RFQPEINLLTNSALWNFSIRKSFATFGQQMLSI 75  yellow fever mo...
Q75JQ3       120 DEEILDLLRSQFMKIFTF--FkP-------------NFI-------HNFQPEINLVLKSVIYKLSIFNLGTTYGNQLQNL 177 Dictyostelium d...
Q00WM0        46 DEELLEILHDQLVRCVDAltLcAtsacgsgddvndSMSSrrrarttFASRERTKLFLDAATFACTTMRNAPTPGQELMNL 125 Ostreococcus tauri
EEC78896      62 DVEMSAMLKEQLVKVFSL--VkP------------GLLF--------QYEPELDAFLEFLIWRFSIWVDKPTPGNALMNL 119 long-grained rice
Q54N40        86 KRIkprnnnangdgdtlfsllkrlvvtpsnagqgpetytksqILKKSfamirrnraaasssqqakddlnTMIQDSDRKES 165 Dictyostelium d...
Q4SN40       119 RYHnl------------------------------------sSASRY----------------------RPLTRRQKWGL 140 spotted green p...
Q28DK5        84 QYKnd-----------------------------------leATKNY----------------------RPLNKQQKVWF 106 tropical clawed...
P55098        84 QHKnd-----------------------------------ssPNPVY----------------------QPPSKNQKLLY 106 house mouse
Q5ZM64        84 QYKnn-----------------------------------lsQTEKY----------------------QPLSKHQKLWY 106 chicken
XP_002026302  78 AYD-------------------------------------------A----------------------EKLTVSRLVLH 92  Drosophila pers...
Q179Y9        76 SYE-------------------------------------------K----------------------EQLGSGKLKAH 90  yellow fever mo...
Q75JQ3       178 TYRnekaf------------------------------dpirGSDQL----------------------NKLTMRQKWLS 205 Dictyostelium d...
Q00WM0       126 RFRderraerd-----------------------eefrrtakTGVEG----------------------DGLTVTQRLAY 160 Ostreococcus tauri
EEC78896     120 RYRderaapi--------------------------tgkevrTGLEG----------------------PGLSVSQKVLY 151 long-grained rice
Q54N40       166 LIYLVLIPYFKGKLDEYYkkesdplaelglvssdnnnnnndnindqiqqleeqiqqqqtivngnnnSNNNNKklkikfli 245 Dictyostelium d...
Q4SN40       141 ALLDIGARWLQERSHSLLlllgl--------------------------------------saggaASQPEG-------- 174 spotted green p...
Q28DK5       107 ALFMVGGKWLEERSFDLFs----------------------------------------------nHPFGAS-------- 132 tropical clawed...
P55098       107 AVCTIGGRWLEERCYDLFrn--------------------------------------------rhLASFGK-------- 134 house mouse
Q5ZM64       107 LIFTVGGRWLEERCYDLFsn--------------------------------------------rqLQSVSK-------- 134 chicken
XP_002026302  93 FVLTVLPGYVKSWEERRL-------------------------------------------------------------- 110 Drosophila pers...
Q179Y9        91 YALTVALAYLKELIQFRL-------------------------------------------------------------- 108 yellow fever mo...
Q75JQ3       206 GLINIGGEWLWTRINRYLin--------------------------------------------nnWSEHPP-------- 233 Dictyostelium d...
Q00WM0       161 GAVKCAGAFAWNAWMAKMarery--------------------------------------deamdEDEDGR-------- 194 Ostreococcus tauri
EEC78896     152 CISTVGGQYIWSRLQSFSaf--------------------------------------------rrWGDSEQ-------- 179 long-grained rice
Q54N40       246 lirflkgsktlKKLKTIFLKVYPfisaIYEALFFIYQLLYLyeYTNYYTPFFHFQNIQLKRLNHKDIeshrvvisnrrrd 325 Dictyostelium d...
Q4SN40       175 -----------GLLALGLRRCFGlvcsVAQIASVVNFLVFLr-KGQHPRLSERIVGARAAFSKPDVVrdvsyqymn---- 238 spotted green p...
Q28DK5       133 -----------FQRTKYFLNai---sgLLKFGALLNFLIFLq-QGKFATLTERLLGIRSVFSRPQDVrqvgfeymn---- 193 tropical clawed...
P55098       135 -----------------AKQCMNfvvgLLKLGELMNFLIFLq-KGKFATLTERLLGIHSVFCKPQNMrevgfeymn---- 192 house mouse
Q5ZM64       135 -----------------IKHYINfgagLLKLCGLVNFLIFLq-KGTFATLTERILGIRSVFCKPQSVrqvgfeymn---- 192 chicken
XP_002026302 111 -----------ARRVEWFSQAIAwaenSALVLNILNYFRFLk-TGRKPTLIDYFLGLDYISLRNNQRrdigykylt---- 174 Drosophila pers...
Q179Y9       109 ------------TGVTFLQRMITivenCLTCLNFINFFRFLr-TGRKPSLVDFILRLDHRSIDGAKRrtigysymt---- 171 yellow fever mo...
Q75JQ3       234 -----------NDIRKKFWNFLNfaesAYKALALLNFLTFLf-NGKYVTLVNRILHMRLVYAHPTLSrnisfeymn---- 297 Dictyostelium d...
Q00WM0       195 -----------GVWKQRAWRWSRaaedAHVVASFVNFCVFLr-YGRYPTLLERFLGARLVYSRPSMArvvdfeyln---- 258 Ostreococcus tauri
EEC78896     180 -----------RPLARRAWGLVQhaegLYRASSFFNLLLFLy-GARYKTIVERILKARLVYESPNMNravsfeymn---- 243 long-grained rice
Q54N40       326 rinfvrdwpgssffvrlvSILDSILDyskyILPLSVFIFKSLEWWYSE 373 Dictyostelium discoideum
Q4SN40       239 ---------rellwhgfsEFLIFLLP----LINTRRLKATASsfvfgg 273 spotted green pufferfish
Q28DK5       194 ---------reilwhgfaEFLIFLLP----LINTQKLKSKLFSWCKPA 228 tropical clawed frog
P55098       193 ---------rellwhgfaEFLIFLLP----LINIQKLKAKLSSWCTLC 227 house mouse
Q5ZM64       193 ---------rellwhgfaEFLIYLLP----LINVQKLKLKICSWCFPI 227 chicken
XP_002026302 175 ---------rellwggfmEILGLVLP----IINFRKLQRLLKSWTSGQ 209 Drosophila persimilis
Q179Y9       172 ---------reliwagfmELLGFTIP----IVNYHALKRRLRnmlkle 206 yellow fever mosquito
Q75JQ3       298 ---------rllvwhgftEFILFIMP----LINIDRIKSFLYRLLvkt 332 Dictyostelium discoideum
Q00WM0       259 ---------qqlawrelsELVLFTLP----YLYNSRVRSFVGAFGSST 293 Ostreococcus tauri
EEC78896     244 ---------rqlvwnefsEMLLLLLP----LLNSSSVKKFLLPFSKDk 278 long-grained rice
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