6P83,6UEC


Conserved Protein Domain Family
LpxD
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pfam04613: LpxD (This model is not part of the current CDD release)
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase (EC 2.3.1.-) catalyzes an early step in lipid A biosynthesis: UDP-3-O-(3-hydroxytetradecanoyl)glucosamine + (R)-3-hydroxytetradecanoyl- [acyl carrier protein] -> UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + [acyl carrier protein]. Members of this family also contain a hexapeptide repeat (pfam00132). This family constitutes the non-repeating region of LPXD proteins.
Links
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Statistics
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PSSM-Id: 516340
Aligned: 378 rows
Threshold Bit Score: 36.3315
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6P83_A                 24 DIVITGVASMQSAQTGHITFMVNPKYREHLGLCQASAVVMTQDDLPF--AKSaaLVVKNPYLTYARMAQ 90  Escherichia coli
Q9PHU0                 18 DIEISALNSLLKANFTELTYCDGEKNTKDIPHTGAAAILVSKEYENLvpKDTkaLITQSPHLSFAFLSK 86  Campylobacter jej...
O24991                 19 DFEVHALAELNKATPNDISYIDQARYLKLLKDSKAGAVFIRKKESSKvpKRMqaLVVDNPHLAFAKASH 87  Helicobacter pylo...
WP_013023658           19 DFELMGIAPLQEANEKQLSYIEQKQYLKDLNDSKAGAVLIRQEFSNLvpTHIqaIITPNPHLAFAQISH 87  Helicobacter must...
Q7VH68                 24 DFELNGIAPLESATPTQISYIDQDKYLSNLTDSQAGAVFIRPHLLDKvpSHIqpLVVENPHLAFALLSQ 92  Helicobacter hepa...
1_pfamImport            1 -RSVARLSSLKDAIEGSLVFVEGKKNADGLSSINAAGVLCSEAVVDSvpSHIaaLVTRNPQRDFASVGR 68 
Q2YRQ3                 33 pRSVERLASLKDAGEGALVFVEGKKNVSSLVGLKAAGVLCTESLADSvpSGIavLVSRHPHRDFSAVGR 101 Brucella abortus ...
TriplettUF:B488_00480  35 NRIIYSIAPIARAKEGDVAYIISRKFIPDLESCYASAIICNSDMRAFipDHIavLLSSSPEEAFALAGy 103
vbi:Avi_2515           34 DRVIRSVAPVYRAKQSDICYILSRRNKAELETCEAGAILCDVALRSLipEHIpvLLIKNPHAAFAIAGQ 102
Q8UFL5                 33 ERIIRSVAPVYRAKPDQLCYILSRKSGEELLTCEAGAVICDAALKSLipSHIpaLISKTPHTLFAQVGA 101 Agrobacterium fab...
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