2IU9,3PMO


Conserved Protein Domain Family
LpxD

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pfam04613: LpxD 
Click on image for an interactive view with Cn3D
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase (EC 2.3.1.-) catalyzes an early step in lipid A biosynthesis: UDP-3-O-(3-hydroxytetradecanoyl)glucosamine + (R)-3-hydroxytetradecanoyl- [acyl carrier protein] -> UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + [acyl carrier protein]. Members of this family also contain a hexapeptide repeat (pfam00132). This family constitutes the non-repeating region of LPXD proteins.
Statistics
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PSSM-Id: 398346
Aligned: 480 rows
Threshold Bit Score: 32.8463
Threshold Setting Gi: 390611293
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2IU9_A          45 TLLSGVEEIEEAKTAHITFLDNEKYAKHLKS-SEAGAIIISRTQFQKYRdlnknflITSESPSLVFQKCLEL 115 Chlamydia trachomatis
Q5NI06          24 VIITGLTYAEQAKENDLTLIDKQEHIKLWQN-SKATAAIVSKKISKELAqvndkplIVVNNADLAMAKILEL 94  Francisella tularensi...
WP_002985937    41 kQIHAAEQLDKAQDGQISFIGNKKY-ERLWAnSKASIAIVNRDISIVPGddr--afIKVDNVDLAMSQLLAF 109 Myroides odoratus
WP_011963712    23 yKITAPEQLELAKETQISFIGHKKY-EKFWQtSKACAAIVNEDISIAPGenr--vfIKVKNADLAMSQVLAL 91  Flavobacterium psychr...
Q6FCG5          25 FNLSGLASLEQAQSHHISFVNGEKYVEAAKQ-SKAGALIVTSAFKDQLPasq--nyIVVKNPYLAFAQLTHV 93  Acinetobacter baylyi ...
WP_013908120    21 LEITGLNALELAGETELSFLESGKFVEAAKN-SRAKAILVSPALAGKIGgk---slLITPNVRAAVAKIGFL 88  Thermodesulfatator in...
jgi:Selsp_1798  24 IVVTGATNIEAAGRTEITFAA-PPHIEEAKA-SAAAAVLLPEDVQDFPLp-----aIHVKEPRAAFAKLLEL 88  Selenomonas sputigena...
jgi:Acfer_1692  23 mVLKGVNGLEEAQNDQISFAV-PPYLEVAGQ-SRAGAIMIPRGAEFKGQqa----vLAVENPRAAFAVLLQL 88  Acidaminococcus ferme...
WP_014128805    23 LKLTGVNGLEEAGPTEISFAV-PPYLELAGK-SRAGAIMIPEEGELKGPqa----lIRVKNPRAAFAKLLML 88  Acidaminococcus
CCX53319        22 VEITETRGLDQAAPQAISFAI-GEYCEHVGQ-SKAGAVIVEAPLADVSIp-----qIVVHNAKAAFAQILQI 86  Veillonella sp. CAG:933
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