2LOM,2LON


Conserved Protein Domain Family
HIG_1_N
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pfam04588: HIG_1_N (This model is not part of the current CDD release)
Hypoxia induced protein conserved region
This family is found in proteins thought to be involved in the response to hypoxia. Family members mostly come from diverse eukaryotic organisms however eubacterial members have been identified. This region is found at the N-terminus of the member proteins which are predicted to be transmembrane.
Links
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Statistics
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PSSM-Id: 516331
Aligned: 183 rows
Threshold Bit Score: 29.3698
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2LOM_A         26 EAPFVPVGIAGFAAIVAYGLYKLKsRGNTK-----MSIHLIHMRVAAQGFVVGAMTVG 78  human
XP_002968560   31 ENKLKTIGTFWGTTLG--SSILW---NLSKph-ekLSLKLLHARVHAQGVTLMALAGA 82 
24_pfamImport   1 EHKLSTVAGVWAAAAG--ASVAYS-RRGAApqraaTSLRLIHARIHAQALTLAVLGGA 55 
ELU44828       99 ENRFGIIGMSWVTAMAVSGGLVFA--R-NRgv--pFSQKIVQVRMYAQGVTIAVLLAS 151
XP_007872717  105 ENKWKIIGGSWVLGMI--GSMSFL-WK-DKyl--tKTQKLVQARMYAQAITLIVLLIS 156
XP_025485223  114 REKYKIVGATWVASMI--GSFAMV-NR-NKhl--sGSQKLVQARVYAQGLTLAVLVAS 165
8_pfamImport    1 ENRYSIVAASWVASMG--IAFGIV-SR-NKyl--tGAQKLVQARVYAQGLTLAVLVAS 52 
XP_016289512  121 ENKFSVVAATWAASMG--GIFAYI--H-TQpm--tFAQKLVQARVWAQGITLASLVGM 171
XP_011390401  121 ENKFSVVAATWASSMV--GIFAYI--H-TQpm--sFAQKLVQARVWAQGITLASLVGM 171
NP_001141245   18 DHELAAIGGVWAAAVG--TSVAYS-RR-KApq-rgTGLRLIHARMHAQALTLAVLGGA 70  Zea mays
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