Conserved Protein Domain Family
SlipAM

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pfam04575: SlipAM 
Surface lipoprotein assembly modifier
Surface lipoprotein assembly modifier (Slam) is a surface lipoprotein that may have a role in virulence. In Neisseria, it is required for the surface display of lipidated virulence factors. Proteins in this family contain an eight-stranded beta-barrel domain.
Statistics
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PSSM-Id: 398328
Aligned: 11 rows
Threshold Bit Score: 308.119
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q5F526         222 WHFSGGISPSVNKNANNAAPQYCL------QGGGSRIcsvTGPVRAAGLDYEAGAEKLTALADNHYLLFRANVGGTSYYF 295 Neisseria gon...
jgi:Asuc_2047  141 WQIEGGFSYIKTNNVENVSDRIDIen---tGFIKSEN---MLPKKANGLAYNLSIGKDFNIYQSHYLSLNNETIGKTYWD 214
jgi:Asuc_1844  196 WQFNVNAGYMREENVNNVSDSLYIen---tAFKKGDS---MLPQKAHGIQFYVGFERDFNLMYSHYLHIENLTYGKAYWD 269
Q7N1G2         207 WRGSFSVGYIFNDNTNMSSDKPPVctlyreNGECAVErklPMAKKANGISYDATLRKIYPLSGHHGVFLRSMTYGESYRH 286 Photorhabdus ...
WP_010846734   164 iKFNTYFSFKRDSNISKITDKKVY------------GwdpNKRIKDVGLSFTPRISKKYFFDSGLFSEFDIDAHGIKYLK 231 Xenorhabdus n...
WP_003671460   252 mgLDLGINYLHLDNINAASTITQP------------NikkDAPKPAHGLALSLGVNKYTPLSHGMSIYTALDVDGKFY-D 318 Moraxella
tigr:DNO_1302  187 WSFGVSGYYVHDSNINQAPDIRSRetd-qcPFAEKCTitfPEKENADGLYLRLNADRRLPIKNNWYANFEGSAHANWYWN 265
RUNMC:MCR_0692 222 WTWQLGMNLAKEDNINQTPKNTTQ-----------GQwtfDKPIDAITLSYQLGADKKWSLPKGAYVGANAQIYGKHHQN 290
Q9K165         204 WKVNGGFSVTREHNINQAPKRQQY-----------GKwtfPKQVDGTAVNYRLGAEKKWSLKNGWYTTAGGDVSGRVYPG 272 Neisseria men...
tigr:DNO_0025  189 WDFYASATYSYDKNVNEAPPVGTKmvfpngSSITSQQ----EPRSANGVEFDFSADKRWNLRGNYFAALHLSTFGKLYWD 264
Q9CKU1         206 WNVYGGVNYLHENNVNNAPPKGTK---------AEGFtpsSQPEKAHGLSYFINLSKNWSLAHGFFTEFSADINGKYYWD 276 Pasteurella m...
Q5F526         296 SRKsaYDDAFGRAYLGWQYKNARQTVGVLPFYQAQLSgsdgfdaktkpPADRRLAPYmlahgaGVQLAHSYRLSRRSQLS 375 Neisseria gon...
jgi:Asuc_2047  215 NHQ--YDDLSNRFFMGYAYKKNDQTIRIRPFYDKRWY-----------GGNSYHWSN------GVQFDYGLWLSSNWQSY 275
jgi:Asuc_1844  270 NND--YTDITNRTYLGYRHKSAKTAWSVLPFYERQWY-----------ATHRYKKAT------GVRGELNHWLNRNWQIS 330
Q7N1G2         287 HSE--ENENTTSAYFGYSYKAQKNDFLMGPVVEFNSV-----------GNHSRYRTT------GIKSEWMNILSENLVLN 347 Photorhabdus ...
WP_010846734   232 EKR--YDFLSTRIGNKIGFEDYSNYFYLKPFYIKSFYgggstssskeiGFKPFYDAI------GFNLFKLSDINENLKYA 303 Xenorhabdus n...
WP_003671460   319 DKS--HNELAVFAHAGLRKDHQKGYVDVVPFVGRIFA-----------TNQQHGRLSprkdsqGVAFGSHHRINDKWQNA 385 Moraxella
tigr:DNO_1302  266 TDQ--YDDIQVRLGSGVGYENARFDASVLPFVSQRFY-----------AGKKYAHAA------GATVSMNYWMTPKWRLS 326
RUNMC:MCR_0692 291 HKK--YNDHWGRLGANLGFADAKKDLSIETYGEKRFY-----------GHERYTDTI------GIRMSADYRINPKFQSL 351
Q9K165         273 NKK--FNDMTAGVSGGIGFADRRKDAGLAVFHERRTY-----------GNDAYSYTN------GARLYFNRWQTPKWQTL 333 Neisseria men...
tigr:DNO_0025  265 EKT--SNDLSSRIGIGGGYSNAVTEIELSPFFSHRWYvnrd---dnnsNFDHYNTGY------GLRLSGSQWLSTKFKYQ 333
Q9CKU1         277 NHK--YDEFSTRLNLGGGYRNAKTEVKLMPFVEQFWYvggenatkdarTLHRYSKSS------GINLDVDYWLTPNWKIS 348 Pasteurella m...
Q5F526         376 VSLERYRQRY--REQgraERNDGWQDGLYVSLARRLGGSATVFGGWQFARFVPkREtvggavNNAAYRRNAVHIGWAQEW 453 Neisseria gon...
jgi:Asuc_2047  276 HTLEYEKRNF--FKN---KEFSGNIKTFSTSLIWYRNPEHIWYIGTTFSRENM-QE------RQYSSDIKNIRIGWLQEY 343
jgi:Asuc_1844  331 TALEYGKEQY--HRN---ALLDGNNKLASATLVWLRTPRQYFYFGGDYSFQRA-QA------RHYGYDLKTARIGWGQEW 398
Q7N1G2         348 LEGEYKQFRY----HklyNHNDGNMASVYATLSYYLTDQTITFAGGDWVNKTS-VE------KADDYQQKGVRAGISTQL 416 Photorhabdus ...
WP_010846734   304 IFYENKNEYY--NKK---KHLNGDINFVSGSLIFIPFNDLYMSLSGSYSVTDR-RS------KEDSHHDKGMTFLISKRF 371 Xenorhabdus n...
WP_003671460   386 FFARMEKGNY--TERy--QGYDGKRYHVNDTILLQDGPNRRYSLGVGYQLSHL-QD------ATKSSHATKIHFGVLQRL 454 Moraxella
tigr:DNO_1302  327 GIYEGEYAQH--DHH---SWLDGQRHYQALNLLYLAHSGRYFFGGVNHYYQDA-QD------DADRFFRYGVNAGWIEDW 394
RUNMC:MCR_0692 352 NAIDISRLTN--HRT---PRADSNNTLYSTSLIYYPNATRYYLLGADFYDEKVpQD------PSDSYQRRGIRTAWGQEW 420
Q9K165         334 SSAEWGRLKN--TRR---ARSDNTHLQISNSLVFYRNARQYWMGGLDFYRERNpAD------RGDNFNRYGLRFAWGQEW 402 Neisseria men...
tigr:DNO_0025  334 GALEWTQNRY----RsdyRHLNGNDYLMSHTLMYLPAARYYWFGGIDYSIRDV-ES------KTNSYDRWGARLGWGQEW 402
Q9CKU1         349 TVLEYTEQRYiqPQR---QNSNGNSYSISNTLIYMPNSQQFWFVGLDYYQKNT-RL------KAYAFERQGIRLGWGQEW 418 Pasteurella m...
Q5F526         454 GGtgGLNSRIAASYAHRNYKGIAAFS-------------TEAQRNREWNVSLALSHDKLSYKGIVPTLNYRFGKTESNVP 520 Neisseria gon...
jgi:Asuc_2047  344 SW--GISTKLSMGATIRQFKAEAILGgil--------plNKTRQDHIYTAIAQLWKRDWHLWNITPKLSLNWKKQKSNLD 413
jgi:Asuc_1844  399 ER--GISTRLGFAVSKREYKADHVLGnvf--------yfSKPREDDIYNINASLWKRDWHLWGITPKLRFNWKKQRSNFD 468
Q7N1G2         417 YP--GINAVVFTVLRQRQFGDYSVPL-------------NARRKDNEQFYAAIVSMPKFEVFGLTPVITYRFRKNNSNVD 481 Photorhabdus ...
WP_010846734   372 LD--DYLVELNYQKIKTDYIGKTTIYtpahifirdlppiKIKREDITDSVSLSLSNESINLFGFYPTLSFSYTKNKSSNL 449 Xenorhabdus n...
WP_003671460   455 PN--GLTVQGRVSAERERYHGKLLRLvn---------pdDVYRTDKTLTLQTSIWHKDIHWLGLTPKLTYRYSKNNSNLP 523 Moraxella
tigr:DNO_1302  395 SG--GLSTRLSASVGKRLYQGADLMA-------------NIKRNDTEYNTGVQLWYRDWHFWGITPKLSLEWNKTNSNHF 459
RUNMC:MCR_0692 421 AG--GLSSRTQISINKRHYQGANLTSg------------GQIRHDKQMQASLSLWHRDIHKWGITPRLTISTNINKSNDI 486
Q9K165         403 GGs-GLSSLLRLGAAKRHYEKPGFFSgf----------kGERRRDKELNTSLSLWHRALHFKGITPRLTLSHRETRSNDV 471 Neisseria men...
tigr:DNO_0025  403 GK--GFATRTTIGYGRKTFDDVDFF--------------NIKQKNNEYSASVSLWNRNFYFGGITPRLTWSYRKVDGNHP 466
Q9CKU1         419 PK--GISTRLQTSYATRTYRAPSAEKnmifa----psffKVVQKNHEYGVNFTIWHRSLHWLGITPKITWAYQKTTSNNP 492 Pasteurella m...
Q5F526         521 -YAKRRN--SEVFVSADWRF 537 Neisseria gonorrhoeae FA 1090
jgi:Asuc_2047  414 sLYSYQE--KNATIVFEKVF 431
jgi:Asuc_1844  469 sLYSYID--RSITVSVEKTF 486
Q7N1G2         482 wLYSYNK--NEVLVKFEKYF 499 Photorhabdus laumondii subsp. laumondii
WP_010846734   450 -FYSYTE--KDIFLDFKRNF 466 Xenorhabdus nematophila
WP_003671460   524 aLYSHNK--QNFYLELGRSF 541 Moraxella
tigr:DNO_1302  460 -YYDRKNgtGRAYIELSKTF 478
RUNMC:MCR_0692 487 -KANYHK--NQMFVEFSRIF 503
Q9K165         472 -FNEYEK--NRAFVEFNKTF 488 Neisseria meningitidis MC58
tigr:DNO_0025  467 -FYNYDK--QNVVVEFSKTF 483
Q9CKU1         493 -FSEYDR--NRIYLTFSKTF 509 Pasteurella multocida subsp. multocida str. Pm70
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