Conserved Protein Domain Family
Herpes_UL20

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pfam04544: Herpes_UL20 
Herpesvirus egress protein UL20
UL20 is predicted to be a transmembrane protein with multiple membrane spans. It is involved in the trans-cellular transport of enveloped virions, and is therefore important for viral egress. However, UL20 operates in different cellular compartments and different stages of egress in pseudorabies virus and herpes simplex virus. This is thought to be due to differences in egress pathways between these two viruses.
Statistics
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PSSM-Id: 282411
Aligned: 4 rows
Threshold Bit Score: 175.445
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P09290  53 DLLLSSACTRTSTVNRSAFTQHSVFYIISTVLIQPICCIFFFFYYkATRCMLLFTAGLL-LTILHHFRLIIMLLCVYRNI 131 Human herpesvirus 3 s...
P10204  42 DFFVSSAYSRLPPHTQPVFSKRVILFLWSFLVLKPLEMVAAGMYY-GLTGRVVAPACILaAIVGYYVTWAVRALLLYVNI 120 Human alphaherpesviru...
Q6UDI5  59 DLFTSAAYSWSEEDELGTRMRASSFFPVASMFAKIICCL-FLLWAkSCTGHGAMVTGLTaCTGAYAIASLLCSFVVYYNV 137 Psittacid herpesvirus...
Q77MS4  63 DYVFTIPNSY---DIHPKFTRYVVLFGLSTFVLRPSCCLIFLFYAiYAQDNRFLILGTT-ITAFFYGTLMLEMYYMYANI 138 Marek's disease herpe...
P09290 132 RSDLLPLSTsqQLLLGIIVVTRTMLFCIT---AYYTLFIDTRVFFLITghlqsevi---fpdsvskILPVSWGPSPA--- 202 Human herpesvirus 3 s...
P10204 121 KRDRLPLSA--PVFWGMSVFLGGTALCALfaaAHETFSPDGLFHFIATn----------------qMLPPTDPLRTRalg 182 Human alphaherpesviru...
Q6UDI5 138 RTDNMPFGTytKLFQIAACIGCGCYALGL---TMEKLFGDSEMYFalfpdaknsplvgatakgsalILPQGCSVAP---- 210 Psittacid herpesvirus...
Q77MS4 139 KYDLMPLSKfqQVLIGALSMLGPIIFVAI---SYNMIFKD--VTFMKK------------------ILAFDTNLKTSgfv 195 Marek's disease herpe...
P09290 203 VLLVM-AAV-IYAMDCLVDTVSFIGPRVWVRVMLK 235 Human herpesvirus 3 strain Dumas
P10204 183 IACAAgASMwVAAADSFAASANFFLARFWTRAILN 217 Human alphaherpesvirus 1 strain 17
Q6UDI5 211 -YVPLaVSV-AYCAAVVYDIADTIFPLLWVRTTLN 243 Psittacid herpesvirus 1 Amazon parrot/1997
Q77MS4 196 IYLVMiASL-AYSITSISDAIGFLLPRLWTRAVLK 229 Marek's disease herpesvirus type 1 strain MD5
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