8G02


Conserved Protein Domain Family
Microvir_lysis
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pfam04517: Microvir_lysis 
Microvirus lysis protein (E), C terminus
E protein causes host cell lysis by inhibiting MraY, a peptidoglycan biosynthesis enzyme. This leads to cell wall failure at septation. The N terminal transmembrane region matches the signal peptide model and must be omitted from the family.
Links
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Statistics
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PSSM-Id: 487179
Aligned: 3 rows
Threshold Bit Score: 36.0777
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
8G02_B 51 MASSVRLKPLNCSRLPCVYAQETLT 75  Escherichia phage phiX174
P31280 50 MASSARLTPLSSSRTPCVLKQDSKK 74  Escherichia phage alpha3
P03640 50 MVLNAPLKPLNCSPSLFLFAPETKI 74  Escherichia phage G4
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