Conserved Protein Domain Family
Pox_T4_C
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pfam04490: Pox_T4_C 
Poxvirus T4 protein, C terminus
This family of poxvirus proteins are thought to be retained in the endoplasmic reticulum. M-T4 of myxoma virus is thought to protect infected lymphocytes from apoptosis and modulate the inflammatory response to virus infection.
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Statistics
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PSSM-Id: 282359
Aligned: 3 rows
Threshold Bit Score: 217.525
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
P25948  77 DEHSFLLTNIRESVYASGHGMYAEI-SNNVTYLDLVSPCARNITIIVSCDDITIN-AYGKNIDEL-HPDVTITTLIDTSC 153 Rabbit fibroma virus ...
Q08FI3  84 NTNEFIVKNVDEAVYGLGRYVYTEMyTRNLSHIELAPKCSKKIHVIVSCDEVSSElTYRQEKHEFgESEVEVTIKIDNTC 163 Deerpox virus W-848-83
Q9PXA3  89 NEHSFLLTDVREAVYASGHGMYVEI-SGNVPYLDSVHQCARNMTVAVSCDNPVPN-AYGKNTDKL-RPGVAIATLIDTSC 165 Myxoma virus

P25948 154 VRGHSFAYSINTLCTERLS--------GESCEQLACQAIKGSQHENYLKACELNAPEQymfKEYKPHQRPHVAKVLR 222 Rabbit fibroma virus (st...
Q08FI3 164 IQHSSSLVQVRSLCEKKLKpvaskyifSSNIGKLTCGFGTVENHNKYLKPCHHGSFDR---SKYNKHQHEHIKKIFY 237 Deerpox virus W-848-83
Q9PXA3 166 VRSHSFAYSVNTLCTERLS--------GESCEQLDCHMVKGSQHEHYLQTCDRNVPDRrtfKAYKPHQRPYVAKVLR 234 Myxoma virus
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