4OC8


Conserved Protein Domain Family
Mrr_cat

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pfam04471: Mrr_cat 
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Restriction endonuclease
Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA.
Statistics
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PSSM-Id: 398261
Aligned: 116 rows
Threshold Bit Score: 53.3428
Threshold Setting Gi: 262080688
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4OC8_A           244 RYKENPFGFEACAGALTRLL-LPDva---rLDLTRPWR-DGGRDGIgrlrI---GQSPAAIEv--DFALEAKCYg-aN-- 310 Azoarcus sp...
jgi:PCC7424_1565 144 FEKLTPKTFDQLVIDLLKKL-GFVn-----SKLNSQIN-ELGIDAI----VefpQKDPFGSEireIYLVETKFY---R-- 207 Gloeothece ...
WP_012279461      17 LSGKAGTRYERLTAMTWKALeGQGaevvhdVRLRGASGvDAQIDVV----V---KRTG-GLR---RVLIECKDFdaaKte 85  Caulobacter...
CAL61872          79 TRAMSWKDFSVEIERALVRD-GFE------VTRIEQ----PQADFS----I---I---SGGR---KALVSCKRW---K-- 129 Herminiimon...
Q21Y78            79 AAAMSWRDFSALIEAAFQRQ-GYV---------VTRPS-HPGADLQ----L---LKDA---R---ITLLSCKRW---K-- 129 Rhodoferax ...
Q7VZH8            79 ARAMSWETFSKVLQEGLRQD-GCE------VTVLQ----GGPADYV----L---RRKN---R---LAVVGAKRW---Ka- 130 Bordetella ...
jgi:Hoch_4159    612 LSAMDLPTLEQVAHIYLLDR-GWKnv--qwIKRVQRSS-YAEVE----------ASDGLG-----TVLVGVRAG---E-- 667 Haliangium ...
CAN95285         478 LSELPGHAFVEICVLALERI-GIGql--raVRRAGAPGgESHFSGA----L---RTA--GDEi--KLALVIRRD---G-- 538 Sorangium c...
jgi:Anae109_2176 248 LRESDAATVEHLAGRLLEQT-GFRe-----IKVAK-----RGREHV----Iy-tARRKMGLAe-lRHGIRVVRN---G-- 305 Anaeromyxob...
Q09AZ5           285 LGELEVGTFEKSVVKMMHAL-HFRe-----LKVAKRSK-EGPL-LT----A---RKREGSVEl--RYAVRLLKG---T-- 342 Stigmatella...
4OC8_A           311 N-AvgVKEVSRLISRIKH----R---EFGVLVTTSYVDRQAYQE-VtD--DgH--P-----VILTTAQDIVGLL 366 Azoarcus sp. BH72
jgi:PCC7424_1565 208 H-S--RPDLRALRQLVEYtkilSe-iDQALLITNGQLTSTAHDW-A-N--DaT--KntgipIRIIDGTELKRLL 271 Gloeothece citrif...
WP_012279461      86 K-KvgVDVVRQFRAVIED----VgdvDAAHIVTCNGFTRAARLY-A-A--RyNi-G-----LAVLKAAQLAQRV 144 Caulobacter sp. K31
CAL61872         130 AaSngIEPLRDLHRAVEA----Gg-aDYSFYITAGDFTPHAMQF-A-V--D-H--K-----MRLVHGAGLAKLL 186 Herminiimonas ars...
Q21Y78           130 AaNtgVQPLQELASAQAT----Lg-aSASTFISLAPVSDSAQRF-A-K--A-Q--G-----IHLMTLAELAQLL 186 Rhodoferax ferrir...
Q7VZH8           131 S-RvgVQALQELNAVRET----Hg-aHDAIYVTIGEISAPALAY-A-K--A-N--Q-----IQFMAEAELTRLL 186 Bordetella pertussis
jgi:Hoch_4159    668 A-AvdRRGVGELRAGVTA----Kg-fTSGLLLAPQELSDTAHAElA-R--KgR--S-----VTALVGDAFVREL 725 Haliangium ochrac...
CAN95285         539 R-EvgRERVTELRGSLHH----YgpaTAGWILTAGQMLSGAREE-A-AivGtA--P-----ISLFDGLAVARLC 598 Sorangium cellulo...
jgi:Anae109_2176 306 A-DasRRDVTELRRDLAH----Yg-aQIGVIISAGEVAREARGE-A-A--AsGqlP-----IVLLCGEALAEAF 364 Anaeromyxobacter ...
Q09AZ5           343 S-TvdRKMVQELRRDLGH----Ys-aQVGLLVSAGEARGDARTE-A-Q--AsG--Al----VMLWCGDALGEKF 400 Stigmatella auran...
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