Conserved Protein Domain Family
Fimbrial_CS1

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pfam04449: Fimbrial_CS1 
CS1 type fimbrial major subunit
Fimbriae, also known as pili, form filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometres. They enable the cell to colonise host epithelia. This family constitutes the major subunits of CS1 like pili, including CS2 and CFA1 from Escherichia coli, and also the Cable type II pilin major subunit from Burkholderia cepacia. The major subunit of CS1 pili is called CooA. Periplasmic CooA is mostly complexed with the assembly protein CooB. In addition, a small pool of CooA multimers, and CooA-CooD complexes exists, but the functional significance is unknown. A member of this family has also been identified in Salmonella typhi and Salmonella enterica.
Statistics
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PSSM-Id: 398246
Aligned: 7 rows
Threshold Bit Score: 136.389
Threshold Setting Gi: 502969503
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
KFD00117             25 VQKDITVTANVDASIDMTLSDGSA--LPKSVEMQYIPGNG---LSPVSMMTKIWSNATTSdagDVHLQLITDPQLINNTG 99  Rahnella...
WP_015698484         23 VQKDITVTANVDATLDMTTDTGDV--LPSTMEMRYMPGVG---LEPVTQSTKIYSNDATK---DVNINLAGTPQLMDTVG 94  Rahnella...
WP_013204479         23 VQKDITVNANVDSTVDMTQADGTA--LPATINMQYIPGRG---LSTYSLDTKIWSNSSTA---NINVALVSTAQLNETVT 94  Erwinia ...
Q6LFV5               30 apQEIKVKTTVGGYMDWSRVDGTA--ISDPIQLQYVANGGhgeFKNLKLNTKVTPEMAGK---KVSFLLKNDLEIVNQID 104 Photobac...
goetting:EBL_c33700  23 VQKDITVVADIDTTIELLQADGSA--LPQTLRLTYLPGVG---LRSENIRTKIFTNDPDQ---KVQVRLLSEPQLLGVTN 94  Shimwell...
WP_011704953         23 VEHQVTVTAQIPTEAFYVQPIGGDdwMSTPQKLAYNPYTK----KLDKLSKQMEAKSTIG---AITGYLTNPAVIA---S 92  Aeromona...
WP_002228181         25 IEKDIRVEAEIISLMDVKRADDSN--I-NKIKLTYDTVTN---DGTYSHSEAIKVKARKQlgdKLKVSLAAPVILSEPNN 98  Yersinia...
KFD00117            100 pEANPIPLNVSWG-GDA-LSVATPidlttAVLFpnGadAANTGS----VAKELQISQATKGTV-ETGMYKGVVSIYLF 170 Rahnella a...
WP_015698484         95 -VNPNIPLSVKYG-DLT-LTQAQQtm-saTTLFpnG--DTTNGS----IIQPLMVSQATQAPV-ASGNYSGVVSVVLT 161 Rahnella a...
WP_013204479         95 --GTAVPLKVTLGaDLKpITTTATsl-tyASLFpaG---TENGS----SVLPLKIAPATVAPL-ATGSYSGVVSLLIT 161 Erwinia bi...
Q6LFV5              105 -QSKIDGFKISVG-GVE-LKTAGN-----VTVV------AEGESgftgVSKALLVTHSGLTSKpADGRYVGFASIVLE 168 Photobacte...
goetting:EBL_c33700  95 pAAAAIPLSVSFN-GAP-LSTTVTni-epTALYptG--VTDNGS----VQMDLTIGQKTLGAVtRSGSYQGVVSLVLN 163 Shimwellia...
WP_011704953         93 -GSDNIALSVKLG-GVA-LSTTSA------EVI--KadDAKTGK----LLELEVIPADAPVTGyKPGNYQGVVNMIFE 155 Aeromonas ...
WP_002228181         99 -NKEFTHVEVLLD-GKKlLETADT-----RDLI------AFHGSe---LNAELKVSAKEPNNAvGGEKYSGVIQLRLe 160 Yersinia p...
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