Conserved Protein Domain Family
ATE_C

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pfam04377: ATE_C 
Arginine-tRNA-protein transferase, C-terminus
This family represents the C terminal region of the enzyme arginine-tRNA-protein transferase (EC 2.3.2.8), which catalyzes the post-translational conjugation of arginine to the N-terminus of a protein. In eukaryotes, this functions as part of the N-end rule pathway of protein degradation by conjugating a destabilizing amino acid to the amino terminal aspartate or glutamate of a protein, targeting the protein for ubiquitin-dependent proteolysis. N terminal cysteine is sometimes modified.
Statistics
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PSSM-Id: 398190
Aligned: 340 rows
Threshold Bit Score: 89.7827
Threshold Setting Gi: 122373005
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EEH60404       298 EFDLYVRYQTAVH-------GDDPSSL---SKH-GYARFLVDS--Pltraeagegvattrdaavgwlrvdsekkdaekky 364 Micromonas pu...
WP_013136246   105 HLNLYDKYHKFMN-------DKKSWPYapiEPIeYSRSYIDGKtsF---------------------------------- 143 Arcobacter ni...
jgi:UWK_02178  120 NIRLCEKFLRSRYphk------------ynDGKsYYKGFFLNR--I---------------------------------- 151 Desulfocapsa ...
ESQ12814       107 SLDLCERFLRTRYphk------------hnTAVgYYSGFFLNH--I---------------------------------- 138 uncultured De...
WP_013163210   100 KLELCERFLACRYpdqecvpGSEGVDG---RAVdYYGGFFLNS--I---------------------------------- 140 Desulfurivibr...
jgi:Despr_2777 118 NLALLQRFLSTRFpeg------------rsSADsYYTGFFITT--I---------------------------------- 149 Desulfobulbus...
Q11T58          85 KEALFEQYKTGVD-------------------------FTASQslhtllf------------------------------ 109 Cytophaga hut...
CAN94079       109 KIILYNRHKHGRGlmr--ddGPLGAEG--------YEAFLVDS--C---------------------------------- 142 Sorangium cel...
Q7UET6         138 RVRLYNDHRNLRGla---hdGDISASD--------YETFLIAS--C---------------------------------- 170 Pirellula sp.
WP_012911596   117 RVELFNLHRELRSlta--geSHLDAEG--------YESFLTLS--C---------------------------------- 150 Pirellula sta...
EEH60404       365 hegkrdagvsassardvqglnhvqpiqtkasvggefvatapscgFGAFHQQYRIDGKLVAVGVVDVLPLSVSSKYFFWDP 444 Micromonas pu...
WP_013136246   144 ----------------------------------------------TKEFLYMRDDKLIGVALTDILDKSISSIYCFYDH 177 Arcobacter ni...
jgi:UWK_02178  152 --------------------------------------------IPGMEFRFRLRGRLVGTGIVDVGQNWMNAVYFYFDP 187 Desulfocapsa ...
ESQ12814       139 --------------------------------------------ITTLEFQYRLDGRLVGGGIADIGENWMNAVYFYFDP 174 uncultured De...
WP_013163210   141 --------------------------------------------TDTWEIAYRVEERLLGLAVVDIAPTALNAVYFYFDP 176 Desulfurivibr...
jgi:Despr_2777 150 --------------------------------------------SRCFEIRYRVGTQLLGVAVVDAAPAWLNAVYFYFDP 185 Desulfobulbus...
Q11T58         110 -------------------------------------gdstvdiYNTLELLIHDGNKLIGVGYFDTGKDCAAGITSFYDH 152 Cytophaga hut...
CAN94079       143 --------------------------------------------CETFEMRYRVGGRLVGVAVVDRGQDSLSAVYSFYEP 178 Sorangium cel...
Q7UET6         171 --------------------------------------------WPTLELEIRHQDQLVGVSIMDIGRDSISAVYTHFDP 206 Pirellula sp.
WP_012911596   151 --------------------------------------------CDTREIAYYLDETLVGIAIIDVGASAISAVYTFYDP 186 Pirellula sta...
EEH60404       445 EYAFLSLGKLGVLREIAWTRSlraecptLRWYYMGYYIHTCPKMRYKAEYAPSELRC 501 Micromonas pusilla CCMP1545
WP_013136246   178 DYEKLSIGKFSILAQIKVAKQl-----kIPYIYLGYWIKDHFSMGYKEAYTPFEVLE 229 Arcobacter nitrofigilis
jgi:UWK_02178  188 DEASRSLGTFNILSMIETCLKl-----dISYLYLGYYIEEVAAMNYKRRFDPHYLYL 239 Desulfocapsa sulfexigens DSM 10523
ESQ12814       175 DEAKRGLGNFNIITMIEFCREk-----qIEHLYLGYYIPTVPAMAYKARFTPHYLRL 226 uncultured Desulfofustis sp. PB-SRB1
WP_013163210   177 DQAHRSPGILNILSLIQLCRQv-----kLEHLYLGYWIKEVPAMSYKSRFKPHQLLL 228 Desulfurivibrio alkaliphilus
jgi:Despr_2777 186 QQGWRSPGTLNILTLNHICATr-----gIDYLYLGYWIDGHAGMGYKQAFRPHELLI 237 Desulfobulbus propionicus DSM 2032
Q11T58         153 AYKKNSLGKYIIMQKIKYCIDq-----qYSYFYPGYFVPNYPAFDYKLSIGTEtley 204 Cytophaga hutchinsonii ATCC 33406
CAN94079       179 ELEPLSPGVFSILKQLELCRSw-----gLRYLYLGLYVERCSRLVYKAQYLPHERLI 230 Sorangium cellulosum So ce56
Q7UET6         207 IASKFSLGTFAVLQQIQWAKDn-----gRTWVYLGLYVAENPHLNYKSRFVPQERLI 258 Pirellula sp.
WP_012911596   187 RVKEVSLGTYSVLQEIALCTTl-----gKKWLYLGYYVSQSEHMRYKGNYLPHERLI 238 Pirellula staleyi
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