2K6W,2JQA,3ZK0


Conserved Protein Domain Family
PCuAC
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pfam04314: PCuAC (This model is not part of the current CDD release)
Copper chaperone PCu(A)C
PCu(A)C is a periplasmic copper chaperone. Its role may be to capture and transfer copper to two other copper chaperones, PrrC and Cox11, which in turn deliver Cu(I) to cytochrome c oxidase.
Links
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Statistics
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PSSM-Id: 516168
Aligned: 257 rows
Threshold Bit Score: 48.6941
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2K6W_A          4 TEGWVRFspGP--NAAAYLTLENPGDLPLRLVGARTP-VAERVELHETFMrEvegkK-VMGMRPVP-FLEVPPKGRVELK 78  Thermus thermo...
WP_023546039   53 TSGRVFLpyGGstETAAFFDVSNLGGADDRLVKVTSTdTRGEITLSRHGT-T----GsGAAYKADVkSVTVPAGGELSMS 127 Streptomyces r...
Q82FL2         39 tGAYMPApsMGt-MAAGFFTVANSGGA-DTLTSVSSD-LSADVTLHSTKG---------GAMEEET-SFPVPAKGQLDFA 105 Streptomyces a...
WP_015659325   32 tgaYMPQpvSDs-MAAGFLTIANDGGTQDELTSVTSD-IAGAVTLHETVD---------SAMQEVT-KLPVPADGHLEFE 99  Streptomyces d...
11_pfamImport   1 ----MPQpvTDs-LAAGYLVIENDGGKADELTSVTSD-IARDVTVHETTG---------QSMQEVT-GLKVPAEGELVLK 64 
Q93J41         56 daAYIPQpvSDs-MAAGFLTITNEGDSADELTSVTSE--AGEVTVHETID---------GTMKEVD-RIEVPAHGQLVFK 122 Streptomyces c...
WP_023548732   50 sgsyiPQpvSAd-MAAGFLTITNKGGAKDELTSVTSD-DAGQVTMHSTMG---------GAMQEQS-SFAIPAHGQLVFK 117 Streptomyces r...
20_pfamImport   1 ---YVPQppMAd-MATGYFTVTNTGAGDDRLTSVSSD-LAPEVTMHSTQG---------GAMRAVS-SFPVPAKGRLVLS 65 
WP_014177871   47 sGAYVPQppTPd-MAAGYVTVTNKGGADDELTSVTTP-LAAEVTMHTTTG---------TRMKQVR-SLKVPADGELRLA 114 Streptomyces
WP_012787268   41 SNAYVREpaNPa-EAAAYFTIANTGGADDSLTAVTAS--TGQASLHTTNG---------AKMVALT-TAPVPAHGSLDFS 107 Catenulispora ...

2K6W_A         79 PGGYHFMLLGLKRpLKAGEEVELDLLFAGGKVLK 112 Thermus thermophilus HB8
WP_023546039  128 PHGVDLTLRARAG-WQAGDLVPFTLHFERSAPvr 160 Streptomyces roseochromogenus
Q82FL2        106 SGGNHLMFEKLTHkpEQGEKVSVKLHFAKSGTVA 139 Streptomyces avermitilis
WP_015659325  100 SGGTHLMFEKLKRkpKEGDTVSVVLHFADSDPVT 133 Streptomyces davaonensis
11_pfamImport  65 SGGNHLMFENLKRkpKEGETVSLRLHFTKSKAIT 98 
Q93J41        123 SGGNHLMFEKLKQqpKQGQSVAVELHFAHSDPVA 156 Streptomyces coelicolor
WP_023548732  118 SGGNHLMFEKLKRkpKQGQTVTVRLTFATSGPLT 151 Streptomyces roseochromogenus
20_pfamImport  66 TGGNHLMLMKLKRrpAVGDKVSFQLHFAKSAPIT 99 
WP_014177871  115 TGGDHLMLTNLTHkpKVGDKVSFTLHFASSDPVE 148 Streptomyces
WP_012787268  108 PGGNHVMIDDpg-pLKPGTSVRLTFTFAASTPIT 140 Catenulispora acidiphila
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