Conserved Protein Domain Family
YdjM

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pfam04307: YdjM 
LexA-binding, inner membrane-associated putative hydrolase
YdjM is a family of putative LexA-binding proteins. Members are predicted to be membrane-bound metal-dependent hydrolases that may be acting as phospholipases. It is a member of the SOS network, that rescues cells from UV and other DNA-damage. Expression of YdjM is regulated by LexA.
Statistics
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PSSM-Id: 398137
Aligned: 98 rows
Threshold Bit Score: 42.8187
Threshold Setting Gi: 123573281
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q5V568            1 M--FvGHALLAFALGALAAWWLGLSRE-RAVQLGVIAglfAAVPD-VD--IVYAPFGLLVGAAENLtadgfw-------- 66  Haloarcula m...
Q1WSF6            1 MqaK-THITTTLALGLPLMSLTNELTL-VNVGVLAVG---SLLPD-ID--HPSSYLGKRHKMVSGVtnk----------- 61  Lactobacillu...
Q9RMV6            1 MkyK-THLTTSLAVALPVLASTGNLTV-GNVIAVSFG---ALLPD-ID--EQHSWIGRRTRGVSDLmnt----------- 61  Bacillus ant...
Q97MS7            1 MifF-GHLGLTTGAVKICENTVLSKKKdIDYRFLLVG---SILPDlIDkpIGAFFFRNVF-------------------- 56  Clostridium ...
Q0W4H6            1 MlfF-GHIGLTLLVVFLVALALKIG---VDYRLVIVG---SLLPDiIDkpLGEYIFHSVFNN------------------ 55  uncultured m...
Q12UG8            1 MfiI-GHLGLTLAIFLVISLLVPSIRNmIDYRFVAVG---ALLPDlIDkpIGRLFFEEIFAN------------------ 58  Methanococco...
Q8TP13            1 MllF-GHLGVTLGIFFGLGIFIPRLRTiIDPRYLAIG---AILPDlIDkpIGEIIFASTFSS------------------ 58  Methanosarci...
CAJ54788          1 MkwF-THKAIAIAGALALEASP------PGLFATLVG---SILPDlAD---RTFAMGNKQQWRRI--------------- 52  Lawsonia int...
Q97LP7            1 MtgK-THAGIGAAVGIALAGKLPGGFNaVGMGLIIAA---SILPD-ID--HPKGMLNQYILPIKSKfiktlfygsfgalv 73  Clostridium ...
tigr:NT01CX1280   1 MkgK-THAAIGMATFMSVYDRVPGGFNyLGVFIVAIA---SLLPD-ID--HPKSIINKYILPFKNKktktavylalaviv 73  Clostridium ...
Q5V568           67 ---------------------etanvvH--R-GPTHSLLLgAALAAAAGLWASNSRATRigslsigavltvltgavsgpi 122 Haloarcula m...
Q1WSF6           62 ------------------------afgH--R-GITHSLLG-FILIGIIVKFIQKQYLTDrien----------------- 96  Lactobacillu...
Q9RMV6           62 ------------------------vfgH--R-GITHSLFG-LVLVLIPILFAVGMTPLSftn------------------ 95  Bacillus ant...
Q97MS7           57 ---------------------------HnsR-IFGHTLLF-SAVLLCIGLYRQLRHKKNg-------------------- 87  Clostridium ...
Q0W4H6           56 ---------------------------G--R-IFSHTLLF-IAVLAIIALLVARKYRywg-------------------- 84  uncultured m...
Q12UG8           59 ---------------------------G--R-IFAHTFLF-VLVLFAMGAIIHKYHKENgtg------------------ 89  Methanococco...
Q8TP13           59 ---------------------------G--R-IIGHTLLF-SLLLFMIGLYIYQRNRdir-------------------- 87  Methanosarci...
CAJ54788         53 ---------------------------H--R-QTSHWMGW-YLLLMILGLMNFPLKHFAlspianq-------------- 87  Lawsonia int...
Q97LP7           74 vfgnyyrfhifmlyilgallfliaissH--RnGLMHSAAG-MIVCTVLVGYVANRYNIHvii------------------ 132 Clostridium ...
tigr:NT01CX1280  74 lysdymytkspvskaigiafifiavssH--RnGLTHSLIG-LISFTIIASYVGKSYAIPasa------------------ 132 Clostridium ...
Q5V568          123 aglvmlvfvlavlgvatvaqsrdvsprtvtglALLGLLT--HPFGDLFTGGPPPFFYPF------------DVTLVAERV 188 Haloarcula m...
Q1WSF6           97 ----------------------------ivfwLMLGYLL--HLLEDSFSQRGVKWLYPFtk---------sGSSFGGKFA 137 Lactobacillu...
Q9RMV6           96 -----------------------------gmcILAGYFL--HLVEDSFSKKGIKWLLPLs-----------nRNFQSGFH 133 Bacillus ant...
Q97MS7           88 -------------------------------iLMLGIGSaiHLILDSMWLYGRILFWPFlgatfptrpeghWLNEGILRL 136 Clostridium ...
Q0W4H6           85 -----------------------------vgvLTVSAAF--HQVEDQMWNAAGTWFWPLfgwgfp-eyergDYILYLLNN 132 uncultured m...
Q12UG8           90 -----------------------------miiLSIASFM--HLLQDRMWTVPQTFLWPImgwefp-hgttyGGFSHYLSV 137 Methanococco...
Q8TP13           88 -----------------------------glsLTAGSFL--HLFEDQMWFDPQTFLWPLfgwsfp-resrdYIGLEHLLD 135 Methanosarci...
CAJ54788         88 --------------------------lfseimLWVGFGGitHVLLDSLTPMGIP-MWPFg----------sKKRIGLSLI 130 Lawsonia int...
Q97LP7          133 ------------------------------yyFMAGYGL--HLLCDMSTSRGIPLLYPFkk---------kNYKFSYTFR 171 Clostridium ...
tigr:NT01CX1280 133 ------------------------------yyFVIGYGM--HLFCDMATKMGIPMFYPFin---------kKYKLPFTYN 171 Clostridium ...
Q5V568          189 MLHpdptthllaafaielatvwlavwtyvhlrgytltglvrpraalglgyaaailfmpaptlEQS-AHFVFSVLALGVVG 267 Haloarcula m...
Q1WSF6          138 FYKt----------------------------------------------------------GQL-SEYLVMGFMLCLLL 158 Lactobacillu...
Q9RMV6          134 VFYys--------------------------------------------------------yNGI-AEKMILMISTIVVV 156 Bacillus ant...
Q97MS7          137 LSDpvy-----------------------------------------------------fssEII-GFVIIMY--YFIKL 160 Clostridium ...
Q0W4H6          133 LISrpdvf--------------------------------------------------lpeiAGL-LALGWFVLRFKLY- 160 uncultured m...
Q12UG8          138 VTAnsfapevs--------------------------------------------ntymfelAGL-SVFIIVVYWQL--- 169 Methanococco...
Q8TP13          136 MFEasfhldfl--------------------------------------------qshvieiLGL-AIGFVLAYYLS--- 167 Methanosarci...
CAJ54788        131 STGs----------------------------------------------------------VGE-LVFLI--ISISCII 149 Lawsonia int...
Q97LP7          172 VGSa----------------------------------------------------------KGTfIENFLIILSLLYII 193 Clostridium ...
tigr:NT01CX1280 172 VNSk----------------------------------------------------------RGNdLEELLIIISLVYII 193 Clostridium ...
Q5V568          268 A-----PTRPF 273 Haloarcula marismortui
Q1WSF6          159 MevrlfWLGNL 169 Lactobacillus salivarius UCC118
Q9RMV6          157 yelysygmasf 167 Bacillus anthracis
Q97MS7          161 I-----KRGKL 166 Clostridium acetobutylicum
Q0W4H6          161 ------KPENA 165 uncultured methanogenic archaeon
Q12UG8          170 ------FRIIV 174 Methanococcoides burtonii DSM 6242
Q8TP13          168 ------KKLIG 172 Methanosarcina acetivorans
CAJ54788        150 S-----QYNWS 155 Lawsonia intracellularis PHE/MN1-00
Q97LP7          194 Y-----RLPVV 199 Clostridium acetobutylicum
tigr:NT01CX1280 194 Y-----RLPGI 199 Clostridium novyi NT
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