Conserved Protein Domain Family
DUF445

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pfam04286: DUF445 
Protein of unknown function (DUF445)
Predicted to be a membrane protein.
Statistics
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PSSM-Id: 398122
Aligned: 74 rows
Threshold Bit Score: 148.538
Threshold Setting Gi: 81766417
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_011723139  11 IVGAIIGYITNWLAIKMLFRPheekrIFgIKIPfTPGLIPKEQKRIAKSVGNAVGEHLLTKDT---MIDALKNNEVDSKF 87  Clostridium novyi
B1YK80        16 VIGALIGAVTNHLAIRMLFRPleakyIGkYRIPfTPGLIPKRRDELAANLGRTVVKHLLTPEG---ISKRLQQPIVYQAI 92  Exiguobacterium...
Q5WHV2        12 VVGAIVGAATNALAIRMLFRPhraysIGkWQLPfTPGLLPRRQKELAVQLGNIVANHLLTAEG---LGKKFGSTAFAAEL 88  Bacillus clausi...
Q5L2A6        12 AVGALIGGVTNFIAIVMLFRPyepmyVFgKRLPfTPGLIPKRRRELAEQLGKTVVEHLVTPEG---LRRKLMDPSFTAEM 88  Geobacillus kau...
Q7NNA7        30 IVGALIGFTSDTLAIKMLFRPykpkyFLgRQIPlTPGLFPKGQERFARKVAQMLTDKLLTPDEvhrIAQRLLTPERLEEG 109 Gloeobacter vio...
Q31P91        14 VVGGIIGYFTNDLAIRMLFRPyrpvvIGgWQLPfTPGLIPANQGRLARRIADAILGSLLTPDAlhdLARRLLELPRLEAA 93  Synechococcus e...
Q2JHS8        11 LAGLVIGYFTNDIAIKMLFRPyrpyrVFgWRIPfTPGLIPQNQPRLAKQIAKTIMGSLLTPEElhnLARKLLQTERMQAG 90  Synechococcus s...
Q10XM6        12 IAGGIIGYFTNDIAIKMLFRPyrpyyIFrRKLPfTPGLIPANQERLAKRVADTIMGSLLTPSElqnLARRLLQTERMEAA 91  Trichodesmium e...
Q8YLP3        21 ILGGIIGYFTNDIAIKMLFRPyraiyIGgRRVPfTPGLIPRNQERLAKNISDTIMGSLLTPDElqkLARRLLKTERVQGA 100 Nostoc sp. PCC ...
Q55115        21 IAGGIIGYFTNDLAIKMLFRPykplfLGpYQLPfTPGLIPRNQERLAKRVSDTIMGSLLTPEElqrLARKLLQRERVEGA 100 Synechocystis s...
WP_011723139  88 KVWANkkvke-vikkNISVKEELrnllgnkiydfinsvrvklsniilTAIKKDEVKVQLEDMIVNSIKEELKKNPEdiin 166 Clostridium novyi
B1YK80        93 TRMIQqevqk-wtrsTKTIREIAer---------------------fVANPEGKLQQQIEQRIDQELESMAVAIKT---- 146 Exiguobacterium...
Q5WHV2        89 TNWLKkqlas-wlrsERTVESILkpl-------------------fqADIGREHLVVQSKSWLKDRLKRYLQKNKE---- 144 Bacillus clausi...
Q5L2A6        89 AEWGRewlrk-wlarKETPAELLer--------------------lgIRSPAERLEAMAAEQAERAYERWSETWRL---- 143 Geobacillus kau...
Q7NNA7       110 LRFALlyalgeysdgRKRARLA------------------------------VALGDILQEVFSESLPKWIDALSRs--- 156 Gloeobacter vio...
Q31P91        94 IAWLVsllle-rlreVRDPRSI------------------------------EVAADVLRDLAGSALPRWLRAIVRq--- 139 Synechococcus e...
Q2JHS8        91 IRWLLgvaldrlqnpEQQQQTA------------------------------QVLARILADLFNESLPRLVKVLARq--- 137 Synechococcus s...
Q10XM6        92 ILWLLqmsld-qlklNTDTKST------------------------------KILANILRDLLGQSLPRLLKVWAKr--- 137 Trichodesmium e...
Q8YLP3       101 ILWLLqlaid-qiktDTDKKSA------------------------------KIVAGILRDLIGESLPRLLKVLARr--- 146 Nostoc sp. PCC ...
Q55115       101 LGWLLqlalk-qireDKQQKTA------------------------------QILANILRDLFSESLPRLLKALARq--- 146 Synechocystis s...
WP_011723139 167 scfyqnitknlldmsigfknssefknylekgiqkkliklenidKPLDEVIPMGVISSL------KVYIYNKNYDIS---- 236 Clostridium novyi
B1YK80       147 -------------------------------------------ARLTEVLGEGGTTKI------KTAIPGMVEVLL---- 173 Exiguobacterium...
Q5WHV2       145 -------------------------------------------VPIKSVVPQELQDRL------TDWLPEASALLL---- 171 Bacillus clausi...
Q5L2A6       144 -------------------------------------------RPIRDVLPAELKQTM------EARVESLAGYLA---- 170 Geobacillus kau...
Q7NNA7       157 -------------------------------------------SASNKIFEQIFDQVAgslrieEAQAVRLAEWIEknvf 193 Gloeobacter vio...
Q31P91       140 ------------------------------------------rQGLDAQIDRWFEQQLlsqklgPLQAQQLGDWLLegaf 177 Synechococcus e...
Q2JHS8       138 ------------------------------------------eTFLEGPINQLFDQVLlelrlsSEQAKQLSEWILkqal 175 Synechococcus s...
Q10XM6       138 ------------------------------------------eYFLEAQINQIFDQILlefqltEIQAAQLSDWLLkvvv 175 Trichodesmium e...
Q8YLP3       147 ------------------------------------------eDFLEAQINQIFDQILlelqlsEEQASRLADWFLevvl 184 Nostoc sp. PCC ...
Q55115       147 ------------------------------------------dNFLSDQINRIFDQILlefrlsELQSRQFADWLLgtvl 184 Synechocystis s...
WP_011723139 237 --MGIKGILKDEKVQlkLQGVFSELISTN---------LNPMVAMFLNP-TTIYNKVYsVLDEYLDREETQK---EVAIF 301 Clostridium novyi
B1YK80       174 --HQTEQYFDSPAGKmkLEETVAQFIQSKl--------gGGMFGMLLAN-VNIVEMIQpELKRVIQGKSTHQ---FISEM 239 Exiguobacterium...
Q5WHV2       172 --KRATAYIDSEEGEqrIGAMVRQFLTTKg-------kVGSMVSMFFSA-DKLTEYVLpEIKKFLHDEQTKE---TVQSL 238 Bacillus clausi...
Q5L2A6       171 --DRTLDYFRSEEGKqqISSMIERFFQERg-------mVGNMLQMLLGN-VNFVDKVQaELGKFLRHAGTRE---VLSRL 237 Geobacillus kau...
Q7NNA7       194 tpDRLRLALINLLTNqtIDTLDKEARERAqgglwlvanVVGIKGPLSRFkSFCVEQPEaANELFTRFLAEAEvreRLTGA 273 Gloeobacter vio...
Q31P91       178 ppDQIRRVMLDFLTDdnIRNLDRIVRDRTrgtdwvianLFGVQSSLQRLrQFLREQPEaGDAVIAELSQRLAlrqQLSQA 257 Synechococcus e...
Q2JHS8       176 ppKVLRQNLVDFLTDrnIESLDEEFRERAtgsywvvanLFGLKNALLRLrTYCLEEPEgAEAILEDLLKDINasrRLTEI 255 Synechococcus s...
Q10XM6       176 ppDVLRKTLIDFLTDqnISIIDEGFREKAsgtywvvanLFGLRNTLTRLrTFCLDERDlTNQRLMELITALAvkeRITEW 255 Trichodesmium e...
Q8YLP3       185 ppDVIRQAIVDFLTDrtIQIIDESFREKTsgtywvvanLFGLRNTLTRLrTFCLDEKEaTNNRLTELIQDLQmrdRFRKI 264 Nostoc sp. PCC ...
Q55115       185 ppDTIRLALVDFLSDrnIQVIDEGFREKTsgtywvvanLFGVRNSLTRLrAFCLEEKEtANLRLKELLLSLEirnRLKDW 264 Synechocystis s...
WP_011723139 302 IN-DIIDKLLKLKLSNIMSQISEDAkikNTEAISDLILKNVVed--------eLFHEILLKLEEKFKEhesieellskan 372 Clostridium novyi
B1YK80       240 VE-QEVHTLLERTVGSLLEPEAERQ---IIERMKSEIVTRIPla--------aLLDTPLHEFLEPLEV------------ 295 Exiguobacterium...
Q5WHV2       239 LQ-TEWHRMLNRPLASFQAENYVDQ---FVDKAAEELEGKIPvl--------nWYNAPLSTWTTPYAE------------ 294 Bacillus clausi...
Q5L2A6       238 LW-TEWNKWLDYPLATVEEMIGRRR---IDEAVRSAARRLVQsg--------sWLHRPLDELIAPYEQ------------ 293 Geobacillus kau...
Q7NNA7       274 LNgLSVQTLSMATVQDLKRQFVTSLtaaLSAQGPGLSQRLGEsidwsrwaaevLDRVVTSEKTLGWID------------ 341 Gloeobacter vio...
Q31P91       258 LQtFQLTDLPQTTLTDLRLQLRQGLrqwLDQDGLSLLEGALGgldwtaaaralLDRLRTAVISDEAIA------------ 325 Synechococcus e...
Q2JHS8       256 LQnLSLQNLPVSAVRQLRRALRDGIqdyLRSQGPEVIKGLGEtidwekvaslvLGRLRNSKALITSID------------ 323 Synechococcus s...
Q10XM6       256 LHsLSMQNLPVSTVRELRNTMQNSVrlyLQENGTDLIQALSLsvawehiadliINRLQASSIMNSSLE------------ 323 Trichodesmium e...
Q8YLP3       265 LQnLTLQNLPIGTVRQLRKTTRETVrqyVQTSGSDLLQGLTDsinweniaellLNRLSNSPVVISSLE------------ 332 Nostoc sp. PCC ...
Q55115       265 LQqLSLENLPVSTVRQLRRTTGEVVrtyIRERGEPLLKDFGSsvdwdnvavliVNRLQSSTAVTGSLG------------ 332 Synechocystis s...
WP_011723139 373 insdkilrdlignklekilksketeekvkVYTDSivNKILESKIcditkgkeeeilnvcdnlaetgfnKFIENEASEFLE 452 Clostridium novyi
B1YK80       296 -----------------------------RISQEmvPMLSKQMV------------------------NRLIEQVEQIMA 322 Exiguobacterium...
Q5WHV2       295 -----------------------------PLVERgvPVIVGMVT------------------------VYMEQHIADILS 321 Bacillus clausi...
Q5L2A6       294 -----------------------------PLFDRliPQAAATVS------------------------CLLSDKIEAIVA 320 Geobacillus kau...
Q7NNA7       342 -----------------------------RIAEGssRLLDRYLT------------------------RELEPLVMKFLP 368 Gloeobacter vio...
Q31P91       326 -----------------------------AFSHEvaLILDQRLE------------------------HELEDLVAAALP 352 Synechococcus e...
Q2JHS8       324 -----------------------------QISADlaLVLERYLE------------------------RDLESLMMQVIP 350 Synechococcus s...
Q10XM6       324 -----------------------------LVSRElaLILERYLE------------------------RDLENIVALAIP 350 Trichodesmium e...
Q8YLP3       333 -----------------------------VVSQElaLILERYLE------------------------KDLEAIVAQVIP 359 Nostoc sp. PCC ...
Q55115       333 -----------------------------LVSEElaSILERYLE------------------------DDLEKIVKQIIP 359 Synechocystis s...
WP_011723139 453 VFDISKIVEDKINTFEVSFAEQIILEIASKELSAITWLGALLGFIMG-----LVSSII 505 Clostridium novyi
B1YK80       323 TLDLETIVREEVDLLDTAYLEEIVLSISRREFRAITWLGGLLGGLIGmi-qaIL-LIV 378 Exiguobacterium sibiricum 255-15
Q5WHV2       322 KLRLEEVIEEQVASFSMAHLEKLIMNITRRELHMITLLGGLIGGIVGli-qaVIVHFF 378 Bacillus clausii KSM-K16
Q5L2A6       321 QLGLADIVRDQVESFSLRRLEAIILSIARRELKMITYLGALLGGLIGav-qgVIGLWL 377 Geobacillus kaustophilus HTA426
Q7NNA7       369 ALGLEQMVITKICNTSPQELEAAIEQVARNELRAIPYVGMVLGFCVGlfevfLITVVI 426 Gloeobacter violaceus PCC 7421
Q31P91       353 ILALEDLIIGRVEATPAADLEAAIQGIVRSELQAIVNIGGVLGVLLGcv-qsLINVWS 409 Synechococcus elongatus PCC 7942 = FA...
Q2JHS8       351 VLNLDQVIADKVNATSPADLEQAIQQIVRQELQAIVNLGGLLGFLVGcv---qVLFLL 405 Synechococcus sp. JA-2-3B'a(2-13)
Q10XM6       351 ILNIDQVIIDRIKGTSAEELEVAVNVIVKNELQAIVNLGGVLGVVVGsf-qtILLVLQ 407 Trichodesmium erythraeum IMS101
Q8YLP3       360 ILSIDQVIVDRVKSTSPADLEAAIEGIVKNELQAIVSLGGILGLIVGlf-qtAFFIFS 416 Nostoc sp. PCC 7120 = FACHB-418
Q55115       360 ILAIDQVIINRINETPAAELETAVQAIVRSELQAIVNLGGVLGLIIGgl-qtGFFLVS 416 Synechocystis sp. PCC 6803 substr. Ka...
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