4TWE


Conserved Protein Domain Family
TFR_dimer

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pfam04253: TFR_dimer 
Transferrin receptor-like dimerization domain
This domain is involved in dimerization of the transferrin receptor as shown in its crystal structure.
Statistics
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PSSM-Id: 398094
Aligned: 293 rows
Threshold Bit Score: 54.1662
Threshold Setting Gi: 674574508
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4TWE_A       619 ISLGPLVTAVEKFEAEAAALGQRISTLQKg-------sPDPLQVR---MLNDQLMLLERTFLNPRA---FP-EERYYSHV 684
RKK83089     778 vFKELKDAATLVQHNVATFEKWEMEWDREvlgnggweaNDIGASrl-aYNNKMAYFETALLDIEIgggiPN-RTQFKNVV 855 Fusarium oxysporum
Q1IMT0       627 LNFAPLDNAVVTFKKSAERYDKAMKALVk---------AGLPTGDktaELNKLLIQSERAYTNAQG---LA-ERPWFKHM 693 Candidatus Kori...
Q01XS4       627 LNFAPLENGFAALLRTAKAYDEALAHAAdn-------gGAGFARAslrDVNARLIAVERALTLNEG---LP-NRDWFKHQ 695 Candidatus Soli...
XP_001364120 644 LSLQWLFSARGDFSRATRDLTNDLFRTD------------TANRLvnrEINDRIMKVEYSLLSPY----VSpKESPFRHI 707 gray short-tail...
AAV66589     648 LSTEWLIAAKSSYSRAATKLNNDIKNSD------------LEDMEmcrIINNRIMKVEHNFLSPY----VSiRDFPFRHI 711 zebrafish
Q5MPX4       647 LTMQWLLSAQGSYDRAASALTSAIRNSD------------LDDMEqcrIINNRIMRVEGSLLSPY----VSpRQTLFRHI 710 zebrafish
XP_015789209 715 LDTDVLSSAIHNFTDSVYNFHLRQGSIDf---------SDPMAIR---TINDQLILLERVFLDP-----VQlYMVNNIHL 777 two-spotted spi...
PDM60816     675 LRFRALITASSKFREAAEALDERVKAITs--------lSKGVSVPmlnAINDRLMRLERVFLDGG----AF-SSPLHKHL 741 Pristionchus pa...
XP_019202984 643 LTGQWLVMASGSYNRVSSILTADIQNSD------------LENMEtcrMINDRVMTVERNFLSPY----VSpIDSPFRHI 706 Nile tilapia
4TWE_A       685 LWAPR--TG-SVV--T-FPGLSNACSrardt----asgsEAWAEVQ------------RQLSIVVTALEGAAATLR 738
RKK83089     856 FGPEAws-ndGAI--F-PAIRDSIEEg------------DWKAAKP------------IVAKTAALLRKAATILEM 903 Fusarium oxysporum
Q1IMT0       694 IYAPGayTGyGVK--T-IPTVHEPMDa------------KKWAQAD------------AGVPAAAKAIEDEAKLvd 742 Candidatus Koribact...
Q01XS4       696 IYAPGfyTGyGVK--T-LPAVRESIEq------------KDWKLAE------------EEIVKVGKVLENAGEAIQ 744 Candidatus Solibact...
XP_001364120 708 FWGSGs--------hT-LSALLDHIKhfnk-----rdgnFNETLFR------------NQLALATWTIQGAANALA 757 gray short-tailed o...
AAV66589     712 FFGNGw--------qT-ATDLENYLQdvrd-----kkasFDIDQVL------------NKFALLTWSIQGCANDLA 761 zebrafish
Q5MPX4       711 LLGSGs--------hT-LAALLDHLEaikg-----glesADIDQFK------------NQFALATWTIQGCANALA 760 zebrafish
XP_015789209 778 IQNPEgl--ySGEneT-LVGLINSLYqifsnphnldaegNNLPTILerg-------lkPRLSILVHAIQNAADIIN 843 two-spotted spider ...
PDM60816     742 VFSPSki--aTAR--TpFALIWETAH--------------DWSTAEhsdkeslletlsESIARLTLAMQTAAELLv 799 Pristionchus pacificus
XP_019202984 707 LLGSGp--------hT-LKALSSDLDalkt-----aspeANAELFR------------NKLAQATWTIQACANSLA 756 Nile tilapia
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