Conserved Protein Domain Family
SirB

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pfam04247: SirB 
Invasion gene expression up-regulator, SirB
SirB up-regulates Salmonella typhimurium invasion gene transcription. It is, however, not essential for the expression of these genes. Its function is unknown.
Statistics
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PSSM-Id: 427816
Aligned: 81 rows
Threshold Bit Score: 60.6523
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6FFN9                5 LITKIIHMTAVALSLLVFVFRAATLF-VgvkgqQPNPVARV---PLIATQHLSFSVVIVTGVILLF---------MKdfq 71  Acinetob...
WP_015465320          3 AFLKHTHLTLILIAVIFFIVNFIWLQ-R-----GHKNAQKAifkKILLHTHLT---VLAFGLILAWllqidpfvsSGy-- 71  Psychrom...
ABM03406              3 SFLKHTHLTLILIAIVLFILCFYWIV-T-----GHKNAQKVifkKILLHTHLT---IALIGLGLMGvlqinpfesQNy-- 71 
RUNMC:MCR_1117        1 -------MLLAIIVLFIFILQALPMF-M-----GKTPKASN---TLKILNHVFYTAVILTGLGLFWq-------iYQvag 57 
CASKLGSI:MRBBS_3199   3 MTLKSIHMLTAYLTVTLFALRLLMDA-V-----GRPGWRQT---PLRWIPHANDTVLLVSAVSLVFvtpw--mplVHg-- 69 
Q3IK93                4 LAVKHSHMAIAMLSVILFYVRSFSRM-G-----SGKLAKNK---LVFIGSHGIDTLLLVSALMLMGiakinpfeqY---- 70  Pseudoal...
WP_011829288          8 PALKSAHMALAGASVGLFTARGLGVQ-W-----RAAWPLRA---GVRRASVLIDSLLLAAGGALWAmlgl--slaHAp-- 74  Methylib...
EHR69564              8 LALRHLHLGAVALSLSLFAARGAAVL-A-----GAAWPMAP---WARRASVLIDSVLLAGGAGLWWllgl--nplRDa-- 74 
CCD31959              6 FEIRAVHIAAALASGGFYLMRALALNlL-----AASWPLSI---VARLASYSVDTVLFTAALMLTAvtrq--yplVDa-- 73 
WP_013262108          8 LLIKSAHVGFVMLSGSVFLARGIGAL-M-----DAKWPTIK---AVRKVSMLIDISLLTAAILLLFalhw--npfVIp-- 74  gamma pr...
Q6FFN9               72 vqpWFYAKIILFV-VLLSSLHKAFkkD-QDILLVQRRAGLIIGAVAFAAIISLVMIKP 127 Acinetobacter baylyi
WP_015465320         72 ---WLLEKLIAFV-AYLFMVNRAL--N-AQKSRPIQWLSFVGAFGWLAYIVYLVTMKQ 122 Psychromonas sp. CNPT3
ABM03406             72 ---WLIEKIGAFI-GYLILVSVAL--N-EKTRKGMRFLAFVGVFGWIVYIGQLVFSKQ 122
RUNMC:MCR_1117       58 tqhWALAKLVLLI-VAASATIKAQ--RhYTNTPSQAKAGLMIASVAYVGIIVLAITKP 112
CASKLGSI:MRBBS_3199  70 ---WLTAKIILLV-GYIVAGLFAL--K-VSVDKRARIVAAVLALLQIAAIFHLATAKP 120
Q3IK93               71 ---WLLEKIVLVV-IYIAVGIVSS----KQTKTAPKVAYTIFNTLVILAIGYLATAKS 120 Pseudoalteromonas haloplanktis...
WP_011829288         75 ---WLLVKLALIV-AYIVLGSFAL--K-RARTPRGRGLAFAGALACVLAIVATALTHD 125 Methylibium petroleiphilum
EHR69564             75 ---WLGTKLLLLL-AYIVLGSFAL--K-RAPSRRARGWCFVAALACVGWLVSVALAHH 125
CCD31959             74 ---WLTMKVVVMLpLYIFLGYWAL----RAKAFKLRLAAMAGAIAAFLFIYSIARTHS 124
WP_013262108         75 ---WLEAKLSLLL-AYIGFGLVTL--R-FAKTQMGKTLGFVVALFCYVLMFSIARAHD 125 gamma proteobacterium HdN1
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