Conserved Protein Domain Family
DUF423

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pfam04241: DUF423 (This model is not part of the current CDD release)
Protein of unknown function (DUF423)
This family of proteins with unknown function is a possible integral membrane protein from Caenorhabditis elegans. This family of proteins has GO references indicating the protein is involved in nematode larval development and is a positive regulator of growth rate.
Statistics
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PSSM-Id: 516127
Aligned: 299 rows
Threshold Bit Score: 40.1919
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_013108610    20 TGAFAAHSLT-------DhfavvyagqtrevageviplarKYLQD-FKTGAEYQMFHGLALLAVGIWalvkqqSgqtasR 91  Planctopirus ...
jgi:Xaut_1480   65 SAAAAAHVGGga---------------------------------nLETAAHFLLFHAAALVGLGALs----lLlgrgrV 107
WP_013946996    33 LSAAAAHKVDsp---------------------------------vLATAATVLTLHAAAAVGIFAVa-----IrsacpK 74  unclassified ...
Q2RPE3          20 SGAFAAHALSalg-------------------------dahGVGL-MEKSARYQMYGAFALVVCAWLa-----ErgvggR 68  Rhodospirillu...
jgi:Bresu_2292   5 VGAFAAHGAGp------------------------------qIKTlLQTGASYQLAHAVLGVVCAGLap--------riR 46 
Q0BVT8          19 MAAIAAHALPd------P----------------------DTIRL-VQTAVQMQGWHAIMMIISALLat---hLhtkagR 66  Granulibacter...
WP_012567112    23 CGAYASHGLPavr-------------------------darAVEL-WQTASQYQLAHAAALLGLVAWr-----RhggadR 71  Rhodospirillu...
WP_011713352    21 FGAYAHHALRpelltidRwe------------------gvA-------LALQYQWYHALALIALDLWh-----PassgvK 70  Magnetococcus...
WP_014805306    17 FGAFGSHVLKasl-------------------------gekFFSV-FQTANQYHFWHTLALLAVALV------RidrpqK 64  Turneriella p...
WP_025229297    19 LGAFGTHALKdr---lsE----------------------KAMET-WHTAVQYHALHALALVVVGLVcayaetK------ 66  Fimbriimonas ...
WP_013108610    92 LLNWA-GWMFLVGVILFSGSLYTL---TL------SGVRVLGA----VTPLGG 130 Planctopirus limnophila
jgi:Xaut_1480  108 VLQLG-ASAIALGALLFSGDLASR---AL------MEVKLLGG----SAPFGG 146
WP_013946996    75 LWSAA-ALLMLLAASVFTGEIAFH---TF------TDNASFRF----LAPIGG 113 unclassified Hyphomicrobium
Q2RPE3          69 LVAVA-GWLHLAGVVLFCGALSAI---AL-----------LGWpagpVAPLGG 106 Rhodospirillum rubrum ATCC 11170
jgi:Bresu_2292  47 LTGLA-GWLSVCGGLIFCLALAFIgllSL---------PPFGA----VAPIGG 85 
Q0BVT8          67 KIALAaGGAFFVGTVLFCGDLYVL---AL------QGI-SLSP----LAPIGG 105 Granulibacter bethesdensis CGDNIH1
WP_012567112    72 LTALA-GAAFALGCLLFPGALYLL---GW------FGPSALGA----VAPVGG 110 Rhodospirillum centenum
WP_011713352    71 RRPFI-GWLMVLGVVLFCGVIYLR---ALnpafelLAK---------LTPLGG 110 Magnetococcus marinus
WP_014805306    65 FFTAA-CWAYLAGLLLFSGNLYLY---AV------YQQRIFAM----LAPLGG 103 Turneriella parva
WP_025229297    67 MVRAA-GWLFAAGIVIFGGTLYAY---AL------TGIVGFAI----VTPLGG 105 Fimbriimonas ginsengisoli
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