2NRK,6N39


Conserved Protein Domain Family
GrpB

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pfam04229: GrpB 
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GrpB protein
This family has been suggested to belong to the nucleotidyltransferase superfamily. It occurs at the C-terminus of dephospho-CoA kinase (CoaE) in a number of cases, where it plays a role in the proper folding of the enzyme.
Statistics
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PSSM-Id: 398075
Aligned: 261 rows
Threshold Bit Score: 92.5704
Threshold Setting Gi: 81675211
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2NRK_A            6 VIVTEYQPAWVEQFEEEAQALKQILken-clKVEHIGSTSVPNLAAKPIIDFLVIVEE----IEKVdlLQWE-F--ER-I 76  Enterococcus...
Q9KMJ4           35 ykADEYQASCENLYRKYELEIAALLpd---asIEHIGTSSIPNAVSKGDLDILVGVN-----GKELenAVKL-L--ST-L 102 Vibrio chole...
Q7MJH4            8 yHAEEYQASCEQRYQKYKSEIEALLpd---avVEHVGASSIPLAVSKGDLDIYVGVD-----REDLesAVKI-L--KG-L 75  Vibrio vulni...
jgi:GYMC10_1203   7 IHLEPYDKQWADRFNDEHRLLIGEIgpy-taAIEHFGSTSVPGMTAKSIVDILVGVEN----TRHTdeILPK-L--AA-M 77  Paenibacillu...
Q5HQZ0            8 fikneSVKQFTYEYNKVKDVLFTILdsp-ikyTQHIGGTCHFNYQTEPILDILVGVNN----LHDItsLDEKrL--NY-A 79  Staphylococc...
Q7UQR9           22 IRLMHHDARWKQEFEQTRSSLLQScqg-hvtQIDHVGSTSISGLIAQPIIDVVALVS-------DLssLDAAsLhiEG-L 92  Pirellula sp.
WP_011101196     44 IQLTAYQSDWQKQATEYQTLLRQQLqan-llKSSHVGSTAMPQLLARPTIDLALLVK-------DQaaAVAT-LhaRPvA 114 Lactobacillu...
CCH31326        117 VELVPYDDGVVAQYEQDRAVVSGVLgll-arEIEPIGSRLVPGIWAKPIMDLLVLVG-----DRDAprAASR-L--AR-R 186 Saccharothri...
WP_012811462    282 VSLTEVSTRHLLAFEREREQISRVFhrrvycSIRHIGTTTVEGAIANDAIDVLVLLRRpvlhREEWh-----aL--EQ-C 353 Alicyclobaci...
WP_015912287      4 VMIVPYDSIWQHLYIGEKKRVLQKLkn--isGIHHIGSTAVPGMDARATIDIAVEVKR------DIe-----aLelAE-L 69  Macrococcus ...
2NRK_A           77 GYe------yXGEFGL--SGRRYLRKgp-----ikRTHHVHIYQFDNTqEILRHLAFRNYLRENPAIATTYGTLKKQLAQ 143 Enterococcus...
Q9KMJ4          103 GFneksdtlrTPelcmle-------------nssgedVAFQVVANGSE--FEFFVGFRDKLRKNPELVQRYNELKISCTG 167 Vibrio chole...
Q7MJH4           76 GFeekqdtlrTPelcmle-------------standdVAFQVVANGSE--FECFLAFRDKLRANPELVQQYNALKMACTG 140 Vibrio vulni...
jgi:GYMC10_1203  78 GYe------nLGESGI--TARIYLRKrg------eLAYNVHIVSYRGD-IWNHNIIIRDYLRAHAVEAERYSEIKRRIVS 142 Paenibacillu...
Q5HQZ0           80 GFyrl----------hhsYKKKVVMArfnnlselkqeVRLHIIQMETS-LFKQYQTVNHLLHNDKAIAEWFASKKNEIVQ 148 Staphylococc...
Q7UQR9           93 NYrvvatpkwLDQSLMlqKPRHGETT-----------HQVLLMVLGNP-AHQRVIQMRDYLRANPEEALRFESIKVDRWK 160 Pirellula sp.
WP_011101196    115 GTthtyatqlAA-------------------------NDIHVIITTDKqHYQQLLTFRDYLNAHRTDGRKYTAIREKGVR 169 Lactobacillu...
CCH31326        187 GFh---------KIPLaeLSRTMLRRyrlgt--gepdLHVHLVGPAVW-AASPEREFYRLLRERPAAAEAYSAVKRLALE 254 Saccharothri...
WP_012811462    354 GYqfcgnagvKG--------RLLWVReaee---swpaVHLQIAKSGNR-YSRAAIAWTRWLQTQQDVLRRWESHKERWVN 421 Alicyclobaci...
WP_015912287     70 GYyli----------cqePRYKVYATkd-------hqFHLFVYNEADE-ELLKRIKLRDYFRTFSSERDRYSTFKWELAR 131 Macrococcus ...
2NRK_A          144 A--Hpd-sIDKYXDGKD----AFIKKIEKE 166 Enterococcus faecalis V583
Q9KMJ4          168 W--S----HEEYRRKKS----AFIERVLGQ 187 Vibrio cholerae O1 biovar El Tor str. N16961
Q7MJH4          141 W--S----QDEYRLKKS----AFVEDVLAq 160 Vibrio vulnificus YJ016
jgi:GYMC10_1203 143 Q--Gar-tLLRYSDEKN----AFVEQLLAR 165 Paenibacillus sp. Y412MC10
Q5HQZ0          149 HakK----IREYESQKQ----NLFEKLYKE 170 Staphylococcus epidermidis RP62A
Q7UQR9          161 Q--Sgg-dPNRYEQDKA----IVFSRLEDq 183 Pirellula sp.
WP_011101196    170 N--Gqa-dLAAYLQTKA----AFMASINDK 192 Lactobacillus plantarum
CCH31326        255 I--Sgg-dPQRYSAVKG----QFIEWlatt 277 Saccharothrix espanaensis DSM 44229
WP_012811462    422 Q--FhrvtLDRYMEGKRtvyaQWsrkkrsq 449 Alicyclobacillus acidocaldarius
WP_015912287    132 I--Ypf-dFSSYKRARD----IFLTVVEvk 154 Macrococcus caseolyticus
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