5L8X


Conserved Protein Domain Family
MtrA
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pfam04208: MtrA 
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Tetrahydromethanopterin S-methyltransferase, subunit A
The N5-methyltetrahydromethanopterin: coenzyme M (EC:2.1.1.86) of Methanosarcina mazei Go1 is a membrane-associated, corrinoid-containing protein that uses a transmethylation reaction to drive an energy-conserving sodium ion pump.
Links
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Statistics
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PSSM-Id: 427786
Aligned: 24 rows
Threshold Bit Score: 270.711
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5L8X_A         6 KREPAPGWPIVSGEYVVGNPESCVGVVTLGSHGLEQACIDAG---AAIAGPCHTENLGIEKVVANYISNPNIRFMILCGS 82  Methanocaldococ...
A6UWH7         4 KKAPASGWPIVSGEYVVGNPESCVAVVTLGSHGLDEAAIEAG---AAISGPCHTENLGIEKVVANYISNPNIRFMLVTGS 80  Methanococcus a...
O32867         4 KAEPAEGWPVVEGDYVVGDPEAPVHVVTLGSHIEEDILKAAGedkVAIAGPCKTENIGIEKVIANVIANPNIRFGVLCGA 83  Methanopyrus ka...
O27227         4 KKSPAEGWPVVNGDYIVGDPESPVAATTLASHIEDVPV-EAG---AAIAGPCKTENLGIEKMIANLISNPNIRFLILCGS 79  Methanothermoba...
D3E045         4 KKPAADNWPVVSGDYIVGDPESPVAVTTLASHNEDIPA-AAG---AAIAGPCKTENLGIEKVVANIISNPNIRFLILCGA 79  Methanobrevibac...
Q2NI29         4 KKEVIQNWPLETGDYAVGNVESPVAVVSLGSNMNDELV-AAG---AAISGPLHTENLGIEKVVANIISNSNIRYVLICGS 79  Methanosphaera ...
O27134         7 KKPVPEDWPHIVGDYVVGDEESPVAVVTLGSHMEDEPV-KAG---AAISGPLHTENLGIEKVVGNVIANPNLRFLVVCGA 82  Methanothermoba...
WP_023991392   4 KKSVQE-WPPVVGDYTIGDVESAVAVVTLGSHMEDIPV-NAG---ASISGPLHTENLGIEKVIANVVSNPNLRFLVVCGA 78  Methanobacteriu...
WP_011833921   4 KKSPANGWPIIQGDYHTGDANSPVAVITMGSHLDEAGICAAG---AALAGSCKTENLGIEKVVANVISNPNIRFVLLCGT 80  Methanocorpuscu...
WP_004079630   4 KRAPASGWPKIQGDYHAGNAESPVAVVTVGSHLDEQGICDAG---AAICGSCKTENLGLEKIVANVVANPNIRFMVTCGT 80  Methanoplanus l...

5L8X_A        83 EVQGHITGQCFKALWENGIgDDGG-IIGAKGAIPFLENVNKEAVERFRRQIvEVVDLIDCEDIGKITQAIKECLSKDPGA 161 Methanocaldococ...
A6UWH7        81 EVQGHITGQCFKALYENGIgDDGG-IIGAKGAIPFLENAGQDAISRFQNQLvEIVDLIDVEDTGKISSAIKDCISKDPGA 159 Methanococcus a...
O32867        84 EVTGHLTGQCFKAMYENGVdPDSGeIIGAEGAIPYLENIPEEAVERYRDQIvELVDLIDVEDVDEIVKAIEECVEKDPGA 163 Methanopyrus ka...
O27227        80 EVQGHITGQSIEALHQNGVdPDKRnIIGATGAIPYIENIPDEGIERFQKQL-EIVNLIDVEDADAIKAKVKECIEKDPGA 158 Methanothermoba...
D3E045        80 EVQGHITGQSIQALHENGCdPEKKkITGATGAIPFVENIPMEGVERFQQQV-ELVDLIDNEDGGAITAKVKECIEKDPGA 158 Methanobrevibac...
Q2NI29        80 EVQGHITGKTVEALYENGIdEEKKsIIGSPGAIPFVENLPVEAVERFQKQV-SIVSMINNEDVSEISSKIDECISNDPGA 158 Methanosphaera ...
O27134        83 EVMGHITGQTMKALHSNGVdLETGrIIGATGAIPYIENMPEEAIERFRRQV-ELVDMVDVEDPDSIAARIQECVVHDSGA 161 Methanothermoba...
WP_023991392  79 EVQGHITGQSIKALHENGAdPEKKrINGATGAIPYVENLNEEAIQRFQDQV-EVIDMVNVEDPHQIQAQIKECLAQDSGA 157 Methanobacteriu...
WP_011833921  81 EVKGHLSGQSIEAMHKNGV-EGGK-IVGSTGAIPFLENLTAEHIKRFQEQI-ELVNIMETEDMGQISAKINELKGRDPGA 157 Methanocorpuscu...
WP_004079630  81 EVKGHLSGQCLHALHANGL-EGGK-IVGAKGAIPFIENLTDESIQRFRDQI-EMVDIMESEDMGAIKAKIDELTARDPGA 157 Methanoplanus l...

5L8X_A       162 IDEDPFIIELE 172 Methanocaldococcus jannaschii DSM 2661
A6UWH7       160 FEEDPMILDLE 170 Methanococcus aeolicus Nankai-3
O32867       164 YEEGPMTISLE 174 Methanopyrus kandleri AV19
O27227       159 FEEEAMVIKVE 169 Methanothermobacter thermautotrophicus str. Delta H
D3E045       159 FEEDAMVIEVK 169 Methanobrevibacter ruminantium M1
Q2NI29       159 YDEDAMIVEFN 169 Methanosphaera stadtmanae DSM 3091
O27134       162 MEEEPLILKVP 172 Methanothermobacter thermautotrophicus str. Delta H
WP_023991392 158 FEEESLVIQLP 168 Methanobacterium sp. MB1
WP_011833921 158 FAADPIVIQLT 168 Methanocorpusculum labreanum
WP_004079630 158 FDGEPIVLEVK 168 Methanoplanus limicola
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