5ICA


Conserved Protein Domain Family
Utp21

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pfam04192: Utp21 
Click on image for an interactive view with Cn3D
Utp21 specific WD40 associated putative domain
Utp21 is a subunit of U3 snoRNP, which is essential for synthesis of 18S rRNA.
Statistics
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PSSM-Id: 398044
Aligned: 117 rows
Threshold Bit Score: 165.047
Threshold Setting Gi: 75015689
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5ICA_C         12 EA-E-EEqa--eDD-GVMAPi-iDQLSADMMTL-SLVPRSRWQTLLHIDIIKARNKPKEPPKAPEKAPFFLPPVGQNGIS 84   Chaetomium th...
XP_015135901  749 dvaegEDkcdemIE--YDSP---EQLGEQLVTL-SLLPESRWKNLLSLDVIKKKNKPREPPKVPTSAPFFIPTVPGLIPR 822  chicken
XP_015192182  670 eyeVeEVtsdemIE--YESP---EQLADQLVTL-SLLPDSRWKNLLKLDIIKKRNKPKEPPKVPKSAPFFLPTVPGLLPQ 743  spotted gar
Q4N972        704 DQtVeSEdenktEEtEFQSTk--SQIEAGLITL-SGLSYSKLQTMLFLDEIKERSKPKEPPKTNDNLPFFLPTTYKDGQL 780  Theileria parva
Q8IDC8        956 depinESekndyVNiMETYTsseNQINKNLITL-SGFNISKIAYLIFLDKIKDKCKVEENVKRNDEIPFFLSTKLDKNIE 1034 Plasmodium fa...
Q550V0        707 eemEdNQvdnndNDaDDNKKstiKQID-QLITLsSDVAKSKWQSLLNLDIIKERNRPIQQNEKPALAPFFLSTIQGLEPK 785  Dictyostelium...
ERN12564      632 sedidtvheqksEGtETSVPysnSQI-PDLVTL-SLLPKAQWQSLINLDLIKIRNKPIEPPKKPEKAPFFLPSLPSLSGD 709  Amborella tri...
XP_006007092  670 AT-EvEEpsdemIE--YDSP---EQLGEQLVTL-SLLPESRWKNLINLDVIKKRNKPKEPPKVPKSAPFFIPTVPGLVPQ 742  coelacanth
XP_022523567  637 DT-DvESl----EMaEYVSP---AQLDEQLITL-SLLPESRWKNLLNLDIIKKRNKPKEPPKVPKAAPFFIPTIPGLVPQ 707  Mexican tetra
XP_030852403  683 DE-EeEKeeeelME--FKSP---DQIGEELITL-SLLPNSRWQSLTHLDLIKKRNKPKQPPKAPKAAPFFLPTVAGLTPK 755  purple sea ur...
5ICA_C         85 SLIPq-------------------------------------------------------------------eDAKAKKE 97   Chaetomium th...
XP_015135901  823 YAAP---------------------------------------------------------------------------- 826  chicken
XP_015192182  744 FGAA---------------------------------------------------------------------------D 748  spotted gar
Q4N972        781 VFVE-----------------------------------------------------------------------PEPEE 789  Theileria parva
Q8IDC8       1035 YKDDkeeqflqnvt-------------------------------------------------nnlenktseqESQQQDE 1065 Plasmodium fa...
Q550V0        786 FAKIdvvnpltiktavstggggsanttgstddnenngepteeelkgwdnwagaddeenddddddednenddqdEDSEDDE 865  Dictyostelium...
ERN12564      710 VSFKp-------------------------------------------------------------------sSIDNSTS 722  Amborella tri...
XP_006007092  743 FAVP---------------------------------------------------------------------------G 747  coelacanth
XP_022523567  708 FGQV---------------------------------------------------------------------------- 711  Mexican tetra
XP_030852403  756 FIAS--------------------------------------------------------------------------SD 761  purple sea ur...
5ICA_C         98 KAAAN----------GASRITKLD--------LTr-QEQTFTSKLLVGGAKGDYTDFIEHLKALPPAAADLELRSLsi-- 156  Chaetomium th...
XP_015135901  827 EQDND----------TQSKVVNIGv-------LA--QKSDFYVHLEEALSTNEYTAPLNLLKDLGPSNIEIELRSLa--- 884  chicken
XP_015192182  749 SSSTE----------GQSKIVNFGv-------LA--QKSDFYHQLEDALVSNDYTGAVSLLKGMGPSSIETELRGLa--- 806  spotted gar
Q4N972        790 IETPK----------PRESLLKS----------Td-SQTQFELLLYSNHE-DKFERMMEYLLEQSPAMVHISLGLF---- 843  Theileria parva
Q8IDC8       1066 QEENQesnveskeivKSKHIGKNSk-------IQi-PSSKLQEILSKNEES--YIKVLKYFKSLSPSGIHYNILCL---- 1131 Plasmodium fa...
Q550V0        866 DEGDEdlekttetfkNEKEIYRSDkviktdslQG--TRTNFNLSLENGYITQNYSESLRILKSLTPSGIDFEIRTL---- 939  Dictyostelium...
ERN12564      723 EKGTE----------NDKGLSRPYs------kWEheSSTLFVQLLHSCSETKTFHEFRDYIKNLSPSTLDMEIRMLqiid 786  Amborella tri...
XP_006007092  748 EQANT----------EQSKVLNLGv-------LA--QKSNFYMQLEDALLHEDYNSPVKLLKEMGPSSIDTELRGLa--- 805  coelacanth
XP_022523567  712 ETPSE----------EQSKVVNLGm-------LA--QKSSFYLQLEGALETNLYEGAVQFLKELGPSAIDTELRSLa--- 769  Mexican tetra
XP_030852403  762 EQTDK----------PSSHVLNLSn-------ME--MKSDLCVLLEKGTSPEHYDAVLKFLKTMSPSRIDMEFRSLd--- 819  purple sea ur...
5ICA_C        157 ------gNGDEATNELLHFIRALTSRLVARRDYELTQAWMTVFLRLHFDLIMENEE--LLQALGEWREHQAReRDRLSEL 228  Chaetomium th...
XP_015135901  885 ------pEGGGSLEVMLSFLRMIGMMLNKKYNFEIAQAYLALFLKLHLKIISSEPS--LLEEISVLSKQLEEtWIHLRSL 956  chicken
XP_015192182  807 ------pDVGGSLDVMQSFLKMIISILDSKRDFDLAQAYLALFLKLHLRLISEEPV--LMDLAREVSTRIEEtWTNMQML 878  spotted gar
Q4N972        844 -------SESNMEETLCEMLRFFQYQVKSKRNADALQVFLHLFLKFHAERLTNLKSsdAKKIMCELKTDLKTaYKLLQES 916  Theileria parva
Q8IDC8       1132 ----------STKEELENMMNFFIYHVKTNDNVDLIQAYLFIFLKAHGKKIMKSKEkkLKNTTKVLLQEIQGcWSNINFL 1201 Plasmodium fa...
Q550V0        940 -------TTADDYADIHYMFDFIVYQLLKNGDYDFIQSILSVTLKVHGYLLYDTT---FKRDLRQLLLVFNEpWFKMQKL 1009 Dictyostelium...
ERN12564      787 dediqepEQRPELLSIGLLLDYFILEVSHGSNFEFIQAVIRVFLKIHGETVRRHAM--LQKKAQKLLEIQASvWQKIDTM 864  Amborella tri...
XP_006007092  806 ------pEGGGSLEVMSSFLRMIGSMMHTRRDFELAQAYLALFLKLHLKVIVEDPT--LLEETSKVSTQLEEtWAHMQTL 877  coelacanth
XP_022523567  770 ------pDMGGDIRVMQSFLKMIGTMLHLKKDFDLAQAYLALFLKLHLQLIAEQPI--LMEEAETILEQLEEtWISMQSL 841  Mexican tetra
XP_030852403  820 ------pVGGGSVLAMRQFISFLHYSLTTGRDYELIQAYLALFLKLHGAMIARESD--LAEELSSLAQIQESsWLRIQRH 891  purple sea ur...
5ICA_C        229 VGYCGGVVSFLR 240  Chaetomium thermophilum var. thermophilum DSM 1495
XP_015135901  957 FNQSLCVLTYMK 968  chicken
XP_015192182  879 FNKSLCLLAYMK 890  spotted gar
Q4N972        917 FDKTSCYIKFLT 928  Theileria parva
Q8IDC8       1202 FENIIFFIKFLT 1213 Plasmodium falciparum 3D7
Q550V0       1010 FHSNICMLRYFT 1021 Dictyostelium discoideum AX4
ERN12564      865 FQSTRCMVTFLS 876  Amborella trichopoda
XP_006007092  878 FNQSMCLLGYMK 889  coelacanth
XP_022523567  842 LNQSMCLLSYIK 853  Mexican tetra
XP_030852403  892 FDQSLCLVKYLK 903  purple sea urchin
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