4C0D,5FU6,5FU6,4BY6


Conserved Protein Domain Family
NOT2_3_5

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pfam04153: NOT2_3_5 
NOT2 / NOT3 / NOT5 family
NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that negatively regulates the basal and activated transcription of many genes. This family includes NOT2, NOT3 and NOT5.
Statistics
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PSSM-Id: 398019
Aligned: 172 rows
Threshold Bit Score: 86.5141
Threshold Setting Gi: 124461811
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4C0D_B        57 YPKFASPWASSPcrpqdidfhvpseYlt------------------------niH-IrDKlAAIKLGRYGEDLLFYLYYM 111
CCE62285     616 pigVNPPTPLDA-------------Fksthqwdmvrt-------slsgslssegSvLlMDsILEKFRNLDSFTLFYNFYF 675 Tetrapisispora ...
Q6CPJ9       595 PSGVFPPQPLDV-------------Arctqqwdq-------------vilslniDgLtVEtVPKEFENLETFTLFYHYYF 648 Kluyveromyces l...
Q6FLS7       628 pyGVNPPSPLDA-------------Frsaqqwdtarh-------slwsslrnneAnFnEEiLMSKFESLDMFTLFYNYYF 687 [Candida] glabrata
XP_004180443 671 pYGVNPPTPLDA-------------Frstqqwdvtccs-----lrdvilsqansKeDkLKkILEKFRSLETFTLFYNYYF 732 Tetrapisispora ...
XP_003674273 618 pHGVNPPTPLDA-------------Frstqkwdivrc------slrdvisksesEtEiYQeIIQRFRGLEMFTLFYNYYF 678 Naumovozyma cas...
CCD22427     660 PKGVNPPTPLDA-------------FrstqqwdiircslrdildsfdaekdnydNsQlYNeILEKFRGLEMFTLFYNYYF 726 Naumovozyma dai...
P06102       650 PQGVNPPSPLDA-------------Frstqqwdvmrcsl--rdiiigserlkedSsSiYAkILENFRTLEMFSLFYNYYF 714 Saccharomyces c...
XP_003956375 626 pAGVNPPNPLDA-------------Frstqqwdl------------ircnlkdlEsLsLNdVLGNFKNLEMFSLFYNYYF 680 Kazachstania af...
XP_003683303 638 plgVNPPAPLDA-------------Frstqqwditrcs-----lrsiiqngdlnDdEkYEaIIEKFRSLEMFTLFYNYYF 699 Torulaspora del...
4C0D_B       112 NGGDVLQLLAAVELFNRDWRYHKEERVWITRApgmepTMKT--NTY-ERGTYYFF--DclNWRKVAK-EFHLEYD 180
CCE62285     676 SVTSMERDIAAKILVERNWIQLSNGVMWFLRQ-----GNIKfaNENsEVADYKIFkaD--DWTVVEKlNFKLDYD 743 Tetrapisispora phaff...
Q6CPJ9       649 SVTPLEQRICALLLKQREWRVLKTGDCWFLRQ-----GAVKfsNDQcEVADYKIFkmD--IWTVVDKlNFKLDYS 716 Kluyveromyces lactis
Q6FLS7       688 SVTPLEKQIASKVLKNREWRVANNEVMWFLRQ-----GEPKlvNDQyEIGDYKIFklD--DWTVIDKvNFKLDYG 755 [Candida] glabrata
XP_004180443 733 SVTPLEKEVSMVVLAERDWRITNNETMWFSRQ-----GEAKlsDELyEIGDYRIFslE--DWTVHEKlNFKLDFG 800 Tetrapisispora blatt...
XP_003674273 679 AVTPLEKEISNVILNERSWRISKDETLWFLRQ-----GSVKlqNEFcEIGDYKIFklD--DWTVIDKiNFKLDYS 746 Naumovozyma castelli...
CCD22427     727 AVTPLEKEIANVILNERNWKVSFDETMWFLRQ-----GPIKfqNELcELGDYKIFklD--EWLVVDKiNFKLDYS 794 Naumovozyma dairenen...
P06102       715 AITPLEREIAYKILNERDWKVSKDGTMWFLRQ-----GEVKffNEIcEVGDYKIFklD--DWTVIDKiNFRLDYS 782 Saccharomyces cerevi...
XP_003956375 681 AITPLEKKISFELLIQKNWKISKDETMWFLRQ-----NVIKfqNENfEISDFKIFklD--DWSVIDKiNFRLDYS 748 Kazachstania african...
XP_003683303 700 AVTPLEQTIASLVLSERNWKVSKSGTLWFLRQ-----GEPKfaNEVcEVADYKIFklD--DWTVADKpNFKLDYA 767 Torulaspora delbrueckii
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