Conserved Protein Domain Family
Gaa1

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pfam04114: Gaa1 
Gaa1-like, GPI transamidase component
GPI (glycosyl phosphatidyl inositol) transamidase is a multi-protein complex. Gpi16, Gpi8 and Gaa1 for a sub-complex of the GPI transamidase. GPI transamidase that adds glycosylphosphatidylinositols (GPIs) to newly synthesized proteins.
Statistics
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PSSM-Id: 397989
Aligned: 58 rows
Threshold Bit Score: 370.06
Threshold Setting Gi: 947043600
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EKC19732     125 GQNVYGILRAKRSASTEAVVLTTPM-Rp--kDSDLPSTTGGIVLMLAMAKYFRRQTYWSKDIIFLVSD---------HEQ 192 Pacific oyster
XP_002619565 118 sDTMYAVMHAARGDNTESLALVVPY-F----TSDGQANIGAMSIAAALARYFTRMSIWQKNIIFVFPH---------DGH 183 Clavispora lusi...
ABN67298     117 nDTLYAIMHAPRGDDTEAMVLTVPW-V----TSEGEYNEGGLALAAGLARYFSKMSIWSKNIIFVFPQ---------DSH 182 Scheffersomyces...
CAR65473     117 tNTLYGIMHAPRGDDTESMVLAVPW-T----TSTGQYNEGGVAISVALLRYFNKMSIWSKNIILVFPE---------DGH 182 Debaryomyces ha...
CCE80716     117 dDTLYAIMHAPRGEDTEAIVLTAPW-S----TSEGSYNVGGIATAVALLRYFKKMSIWSKNIILVLPE---------DGH 182 Millerozyma far...
Q9US48       123 GSNFITTLRAPRGDATESLLLCVPW-K----DHIGQYNEAGVALAISLLKYFQGWSLWSKDIILVIFD---------DPV 188 Schizosaccharom...
CCA69779     129 GVNAYGTFRSPRTSGAEAIVIVASWiSredeGQKRQPNLRGIATVLSLANNLRRQSVWAKDLIFLVSD---------SYL 199 Serendipita ind...
EGF76976     144 GYNIHGVLRAPRGDGTEAMVLTAPL-T----LADNAFNANGIRYLLQLAKFLKKYSFWSKDIIILVTT---------NNA 209 Batrachochytriu...
Q95X60       136 GENVYGFIRGPRNDGAEAQMIVVQLgR-------SEKSRRMMSRMLAFVDYAKDQVYWARDIVIVFVDggekndsieKAA 208 Caenorhabditis ...
EFO84723     120 GENVYGFIRGHRNDGAEAQLIVVQLgR-------SESARRMISRMLAFIDYAKEQVYWARDFVIVFVDggdkkesidQAA 192 Caenorhabditis ...
EKC19732     193 IGLQAWLDGYH--DIKSEy-----iVPSDV--MGRSGAIQAAINLEI---PDGnIRYFDIKIEGMNGQLPNLDLFNLVV- 259 Pacific oyster
XP_002619565 184 AVLRSWVEAYH----------------SSL--DDTPGSIEAAIVMEYa-sALDnFSHMELFYEGLNGQLPNLDLINTVT- 243 Clavispora lusi...
ABN67298     183 AVLRSWVEAYH----------------TTL--EQTAGSIDAAIVLEYg-kNGDyFDYFEMYYEGLNGQLPNLDLLNTIS- 242 Scheffersomyces...
CAR65473     183 ASLRSWVEAYH----------------TSL--DRTAGSIEAAIIMEYe-gVADyFDYYEINYEGLNGQLPNLDLLNTAN- 242 Debaryomyces ha...
CCE80716     183 VALRSWVEAYH----------------TSL--DETAGSIEAALVIEYg-sASDhFDFYEVVYEGLNGQLPNLDLMNTIN- 242 Millerozyma far...
Q9US48       189 YGPSSFLTSYF--DQTTPy-----iSYTPL--KIRSGSIQAGLSLELv-tTENnSDVLEVLYQATNGQLPNLDLFNTIS- 257 Schizosaccharom...
CCA69779     200 DGAHAWLSEYHgssq-------kglVAQPLndPEPAGVIWTALVIDY---PGHsFSHLGLFFEGTNGRLPNQDLSNSL-- 267 Serendipita ind...
EGF76976     210 YGTYSWLQAYH--GFKPDvkq--glIFDSL--DTHAGSIQSAISLEFp-gTED-YTSIGIFPEGINGLLPNADLVTTIIl 281 Batrachochytriu...
Q95X60       209 FALDAFLLKYQkiEALNSkks-itvEADEI--QAQTGALIGGVVYDLsgmAVKgQHIVNIQTNGLNGQQVNLDVFNGIT- 284 Caenorhabditis ...
EFO84723     193 FALDAFLFKYQkiEALTSkqsngtvIADEI--QSQTGALIAGVVYDLsgmSIKgQHIINIQTNGLNGQQVNLDVFNGIV- 269 Caenorhabditis ...
EKC19732     260 KICNQE-GVDVSFHRNFDPMDpqs--------------vdGYVQSVKTMLEMMWSQAAGTP---SGNHGLFHKYHIEAVT 321 Pacific oyster
XP_002619565 244 TIARNE-QIKVSIQGAAGDDLdr----------------nTYFTRLRTLLTGILNLAISGLsetGPGCESFSGWQIQAIT 306 Clavispora lusi...
ABN67298     243 NVAYHE-GIHCVIQNTPSTELvr----------------nDYYSRTRTLLRGILNLTLSGLkrdVPGCAAFSGWQIQAVT 305 Scheffersomyces...
CAR65473     243 TVGHHE-NLQCSIQSTPANQLst----------------nTYFSRLRVLFRGILNLALAGLnrnTPGCEAFSGWSIQAFT 305 Debaryomyces ha...
CCE80716     243 LIGYHE-NIGYSIQGTTRDELqk----------------rTYSTRLRTLLKGILNLALVGLkkkTPGNEAFSGWQIQAVT 305 Millerozyma far...
Q9US48       258 RIFMQHfNYPLRLQGYDFHANsg----------------sSYTSRLKSLWMGMLTQAVSNV---TSAHALFPQYRIDMLT 318 Schizosaccharom...
CCA69779     268 SVISRNmGVPLVLYDHKDDQIhrgpailqpladlfdinlpDYVRRVRNIGRHVSYQAIGEP---SGVHGLFHRYRIDAIT 344 Serendipita ind...
EGF76976     282 SISDPYyGSPLELHHGDHKTVgys-------------mtdQYLACIKRLWRFIGYQASCMP---KASHALFLQYKIEAIT 345 Batrachochytriu...
Q95X60       285 KIADSKhHSRVAIFGTLHRHSnp----------------yMEYSPFIVPMRALYTQAFISI---EGIHSVLGKYGVQGLT 345 Caenorhabditis ...
EFO84723     270 KIADSKhHSKVAIYGLMHRHAsp----------------yKDYSPYDVPLKALFTQAFVSI---EGIHSVMGKYGVQGLT 330 Caenorhabditis ...
EKC19732     322 L--QGIRrknsNYAFPLERTGRILEGIFRSLNNLLERFHQSFFFYILPGTRNYISIGMYMPPFGLIcATGLIKISLLLFL 399 Pacific oyster
XP_002619565 307 I--RAVG----EGGPDITQFGRIVDSTFRAVNNLLEKFHQSFFFYLMLTPLNFVSIGTYLPSAALL-VASFAISSI--YC 377 Clavispora lusi...
ABN67298     306 I--RAKGt---QGPHDVTQFGRVVDTSFRSVNNLLEKFHQSFFFYLMLSTKHFVSIGTYLPAAVFI-AVSFAFSALGCLL 379 Scheffersomyces...
CAR65473     306 V--KARGt---SGPADVTQFGRIVDSTFRSVNNLLEKFHQSFFFYLMLAPNHFVSIGTYLPSAILI-AVAFAISSFGCLL 379 Debaryomyces ha...
CCE80716     306 V--RAKGv---DGPSDVTQFGRIIDSTFRSVNNLLEKFHQSFFFYLMLSPDNFVSIGTYLPAAVLL-AVAYVLSSLGCLV 379 Millerozyma far...
Q9US48       319 LrmKVKD----PFSFDMFRFGQAIESTFRSLNNLLEHLHQSFFFYFILDHLHFISIGNYMPSILIL-AASFMLGAYRHWI 393 Schizosaccharom...
CCA69779     345 L--YTVPa---TGPHGFHSLGRVIESLLRTTNNLLERLHASFFFYLFTAPSEFAEFARYLPPVIIL-GLAASFGGLHLYV 418 Serendipita ind...
EGF76976     346 L--RGLVipgfSQSVGAIQVGQILENALRSFNNLLEKLHHSYWFYFMPTASEFIPISVYIAPVAIL-ASSIIIFSIGKWW 422 Batrachochytriu...
Q95X60       346 Vg--------lSHDYSEKQTGQFIEEVSRMLNNVLERLHQSYFMYVLADDLHFSSIAMYIIPLTIL-VSPLVISA---YF 413 Caenorhabditis ...
EFO84723     331 Vg--------lSHDYSERQAGQFIEEVSRMLNNVLERLHQSYFMYVLSDDMHFISIALFVIPIGIL-ISPLVFLV---YF 398 Caenorhabditis ...
EKC19732     400 pVENEDKEKKKEKEKsekeGEEDedregkhteeeldkeveelrktimdedveeEAAAEGLIS--IMPVILISL---MMG- 473 Pacific oyster
XP_002619565 378 lATGVSTKDYISE-------------------------------------------IGHVLT--TFTGIEFAC---LVAs 409 Clavispora lusi...
ABN67298     380 -NSGVEASSFFNN-------------------------------------------TGSLLF--IFTVIELSS---GVLa 410 Scheffersomyces...
CAR65473     380 -NSGLQMSLFLGT-------------------------------------------FNKLLI--FFTSVESVC---FTIs 410 Debaryomyces ha...
CCE80716     380 -INEVQAKFIAQS-------------------------------------------AYKILT--IFIFVELGC---LMLa 410 Millerozyma far...
Q9US48       394 nH------------------------------------------------------EKKIDLwrPFSFWLFSIfctIAA- 418 Schizosaccharom...
CCA69779     419 qTGWIQHEERSEKDDeddeGKLVwhmr-----------------------drpVLE--------VLCIMGATH---LVGi 464 Serendipita ind...
EGF76976     423 eTPFALIASKNLKIDq---------------------------------------sASSIYVhrVLGVTSFTH---FVRp 460 Batrachochytriu...
Q95X60       414 eWTKIQEFQ-------------------------------------------------------FPVVHLAFH---VLG- 434 Caenorhabditis ...
EFO84723     399 eWKKCQVFH-------------------------------------------------------FPLTYPFIH---FIG- 419 Caenorhabditis ...
EKC19732     474 ----VFSYTGPDFitmsapp--------------frikmedNISFGLMALYTASLMVPRLISRKQP-------GAgKKLi 528 Pacific oyster
XP_002619565 410 ialtKFVVVLPDFls---------------------------pLLVFLFAGSIVLSLCPSISILPHr------KLsKPM- 455 Clavispora lusi...
ABN67298     411 aalpWITFGSPAEyq--------------------------dTTVAQILFVLSLLTFGLAFTPLIMtkt-kkvKFsKSI- 462 Scheffersomyces...
CAR65473     411 illpYLVKLSANEek---------------------------lGVNIVLYGLIYNSVAISISPNFNipslkkyKLsKEL- 462 Debaryomyces ha...
CCE80716     411 ktlpLFVLGSDDDes----------------------------vAALILYGFTVLTFASFVLSIKNqwipkkyRMdKSL- 461 Millerozyma far...
Q9US48       419 ----YYLVSSSTKit--------------------------vFIFLYLMLTFIGIIFSTFMTSE---------------- 452 Schizosaccharom...
CCA69779     465 atlaIVHQAWFWAlvqe---------------------adlSLAIGIVSVPSVLLLLAVGVYSFAIrpl---------pp 514 Serendipita ind...
EGF76976     461 mflpLLTLATSFGacswmmvniet-------ityisamrtdLFALVETTIIGLQIFLVYYIMPFVHrlaygsgAStKTSv 533 Batrachochytriu...
Q95X60       435 ----FFYYIATTYvfqtigttfvlqwmqwpfvgidgcdgqfTPSWSLINSFLIFFMIPLGPYVFLKep-----------v 499 Caenorhabditis ...
EFO84723     420 ----YMLYLFTTWtykhvgtryvfqwtqypfigkegcdgafSPLFDLMHSFLLFSVVPFGLYAFYKvp-----------v 484 Caenorhabditis ...
EKC19732     529 fDWQLLKCVTLLYQSLFLFSVSLMNISLAFFLAVIL-MPITVIVQ----------------------PTKI---RLLLWI 582 Pacific oyster
XP_002619565 456 -SYSLL-AFSLYFIAMLIVSLLIVHFALALCLGACA-FPLSLIPAlik-----------------qsVDKKssaSKINTK 515 Clavispora lusi...
ABN67298     463 -TFGLI-SLSLFYISMLITTLLIVNFSLALTVGLLS-LPLTFIQPiisqks-----------nltksPQVVsnrKRAQVK 528 Scheffersomyces...
CAR65473     463 -TYMLI-SMSLFWIALLITTLLIVHFALALSIGFFA-LPLTFIQPiitna------------nlkslGKANnskYLSKIK 527 Debaryomyces ha...
CCE80716     462 -TFCLI-ALALFLISLLLTALLIVNFALAFLIGLAA-LPLTFIQPlvttsnlkllsespkekrkdllSYLVndgNSKRLK 538 Millerozyma far...
Q9US48       453 -DAELVLSYDLMSKSLFISVVSTLNFSLSFVVAILL-VPLQFISFrf--------------------------nRRLSLL 504 Schizosaccharom...
CCA69779     515 tTPALLKALNLCCLGVVISVIAVANFSLSVTIAVLAtVPLCLVPVrldqp------------itenvSKLVklqPVLRPA 582 Serendipita ind...
EGF76976     534 pAWKIVRLCCCCVLGVFLFMLAGINPSLCILVALPY-VPVFLFIR-------------------------PttsKVLRIA 587 Batrachochytriu...
Q95X60       500 rCVPSMRIVCLLETSLVLYGICLTNFGLAILCTAFV-VPIVFL------------------------MTYEssdRTRSIF 554 Caenorhabditis ...
EFO84723     485 pCVPTMRIFCLVETTLAIVALALTNVGLGIFTSAVV-VPVVFL------------------------MTYEsyqRERSIF 539 Caenorhabditis ...
EKC19732     583 QKFFL-------------LLVSPGVLLFIAAVItSYGEKHAdfldllvnswsfmktNIFLTIID---------KY----- 635 Pacific oyster
XP_002619565 516 ISLCL-------------LASSPVTAIVA----------LGytlsngk--yegalfLIKGLLSA---------WR----- 556 Clavispora lusi...
ABN67298     529 VSLCL-------------LVSSPWFVVFL----------AGsyldp-----engisLMRGLLTS---------LH----- 566 Scheffersomyces...
CAR65473     528 VTACL-------------VMSSPIFIIYL----------IGnvfihe---dqgptvLMRGLLTS---------WN----- 567 Debaryomyces ha...
CCE80716     539 IGLCL-------------LVSSPFFIIYI----------IGnlfvde---skgaliLMKGLLTS---------WD----- 578 Millerozyma far...
Q9US48       505 FAVLTyfstfiflcslskILNGPLVPF----------------------------------------------WLwakey 538 Schizosaccharom...
CCA69779     583 AVAFV-------------LLISPMGLLqcarsl------------------galypTLTDVAISgwlrrilweAV----- 626 Serendipita ind...
EGF76976     588 QIVLL-------------NLLSPPGYLllacflyg--------------dtavvaqAVKDAVFD---------WH----- 626 Batrachochytriu...
Q95X60       555 RSSVL-------------AILNPISVLAFVAIN-IPGMFGQlfptisqdswlaaaqSIALTAIRed-------------- 606 Caenorhabditis ...
EFO84723     540 RSGML-------------AILSPMVVLTVVAYS-LPAFITViipdkayqtvigvpvFMLQTMIQtd-------------- 591 Caenorhabditis ...
EKC19732     636 -FFGSWMFSLFSFV------------ILPNWLM 655 Pacific oyster
XP_002619565 557 -EMQCWTWFVLSLG------------WFPAWIA 576 Clavispora lusitaniae ATCC 42720
ABN67298     567 -ELQCWTWYVVILG------------WFPAWLT 586 Scheffersomyces stipitis CBS 6054
CAR65473     568 -ELQCWTWFIIILG------------WLPAWLI 587 Debaryomyces hansenii CBS767
CCE80716     579 -ELQCWTWFIVILG------------WFSAWST 598 Millerozyma farinosa CBS 7064
Q9US48       539 eLFNSWLMPSVFMIlvlpeiifsvtsFFSLWNE 571 Schizosaccharomyces pombe 972h-
CCA69779     627 -ILKTWFVPITCAV------------YLPLVLQ 646 Serendipita indica DSM 11827
EGF76976     627 -FFGSQLVPFVCLL------------IWPLNLT 646 Batrachochytrium dendrobatidis JAM81
Q95X60       607 vEFKVNHFFLLCCF------------GYPIWNM 627 Caenorhabditis elegans
EFO84723     592 aANGSWHLFLMTCV------------AWPVWNM 612 Caenorhabditis remanei
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