pfam04106: ATG5_UblB (This model is not part of the current CDD release)
Autophagy protein ATG5, UblB domain
ATG5 is directly required for the import of aminopeptidase I via the cytoplasm-to-vacuole targeting pathway. ATG5 is conjugated to ATG12; this conjugate exhibits E3 ligase-like activity which facilitates the lipidation of members of the LC3 family, and therefore autophagosome formation. ATG5 comprises N- and C-terminal ubiquitin-like domains (UblA and UblB) that flank the helical-rich region (HBR). This is the UblB domain, found at the C-terminal.
Jiyao W et al.(2023). "The conserved domain database in 2023.",