4I98


Conserved Protein Domain Family
SMC_ScpB

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pfam04079: SMC_ScpB 
Segregation and condensation complex subunit ScpB
This is a family of prokaryotic proteins that form one of the subunits, ScpB, of the segregation and condensation complex, condensin, that plays a key role in the maintenance of the chromosome. In prokaryotes the complex consists of three proteins, SMC, ScpA (kleisin) and ScpB. ScpB dimerizes and binds to ScpA. As originally predicted, ScpB is structurally a winged-helix at both its N- and C-terminal halves. IN Bacillus subtilis,one Smc dimer is bridged by a single ScpAB to generate asymmetric tripartite rings analogous to eukaryotic SMC complex ring-shaped assemblies.
Statistics
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PSSM-Id: 397962
Aligned: 101 rows
Threshold Bit Score: 126.123
Threshold Setting Gi: 118195113
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4I98_B   5 AKIEALLFVAGEdGIRVRQLAELLslP---PTGIQQSLGKLAQKYEkDPDSSLALIET-SGAYRLVTKPQFAEILKEYSK 80 
Q9HKK2  10 RKVEAILYSSRS-PVSIKLISQIL--Sa-dPLSVRKAVINLKKNYE-KRDGALEVASY-GYKYRIQLKSQYFSEAYAVSP 83  Thermoplasma acidophilum
Q6L0G6   6 RKVEAILYSCEE-PLKVSDIADYLkv---sNDDVIRAMKLIARSYN-EINSTLEIKKI-GNKYKIQLSNDFNDVVYPFVK 79  Picrophilus torridus
Q8DKL3  12 MRVEAILYLKAQ-PLTLTELATLA--Gt-dREAIELALIELLNDYA-HRQTALEIVQI-DDKYSLQLKSAFQELVQSLVP 85  Synechococcus elongatus
Q7NJH4   8 TRLEAVLYLKAR-PLNLEQLSRYA--Ec-dRDDCREALLELLEDYA-GRDSALEIADT-ATGYALQLRPPLQDLIQRLVP 81  Gloeobacter violaceus
Q2JQ06  29 NQIEAILYLKGQ-PLELSALAQLA--Hc-sRDEAYDALLELMEDYA-HRDSALEVLQV-EEGFALQLREPFLELANQLLP 102 Synechococcus sp. JA-...
Q0W2M2   6 NLLEAALFAAGG-PITDAQLKALI--Nr-sSAYVAQIMDQLIDEYR-SRGSPLEIIRL-DGKYVMQLKPEYSSKVMSVSP 79  uncultured methanogen...
A0B6Q9   5 ALVEAMLFAAGR-PLSVEEISGLS--Gl-dAKDVLDAANSLLREYA-SRGGGIEVRAV-EGSFVMQVRGDLAQSVAMVAP 78  Methanothrix thermoac...
Q5JDN0   8 ALVEAALFVAGR-PLSLKELSKAL--GiksLEYLEKLIELIAAEYA-ERKSAIEVVRVlEDKYVMQVKQEYSQRVIHLMP 83  Thermococcus kodakare...
O28692   5 KIVEAILFSSSE-PVDARELRKIT--Gk-dKVEILNAIGELIKDYE-SRDTSIEIIKV-GEKYLMRVKPQYAEYVERFTV 78  Archaeoglobus fulgidus
4I98_B  81 ApinQSLSRAALETLSIIAYKQ-PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGrPNLYVTTDYFLDYXGINH 159
Q9HKK2  84 P----DISRSEMKVIANIAISDvGLSATAIKKIAHQRTDQILSHLEDMGLVKLIN----KGnSKIYTLGRKFESYFGISK 155 Thermoplasma acidophilum
Q6L0G6  80 K----DLDKRDIAMLSYIYGKP-GVIAGELRENFGYNFMESVKKLKAEKLITSHKYRNT----FKYHVTKNFYVRFNVKD 150 Picrophilus torridus
Q8DKL3  86 V----ELGVAAQRTLALIALRG-PIRQPEVIALRGANAYQHIQELLTLGFIRRRRDS--QSrSYILQVTERFHQYFQV-- 156 Synechococcus elongatus
Q7NJH4  82 A----DLGVGAQRTLALIALKG-PLPQSELVELRGSGAYDQVRDLVGKGFVSRCA----EGrSYKLRVTEKFFQYFAI-- 150 Gloeobacter violaceus
Q2JQ06 103 P----EIGVGATRTLATIILRG-PLSQAELVELRGQGAYQHVAELVEKGFVTRYRKE--GSrSPWLRVTDKFHRYFMV-- 173 Synechococcus sp. JA-...
Q0W2M2  80 K----ELSPGVLRTLSIIAYYQ-PIFQNELVNIRGQSVYDHVAVLLDRGLIEKTK----EGrSFKITTTPAFCDYFGLTH 150 uncultured methanogen...
A0B6Q9  79 R----ELDSSVIRTLAVIAYRQ-PIMQSELARIRGNKCYEHVRLLERMGLISASK----KGrTRELRTTRGFAEYFGLQS 149 Methanothrix thermoac...
Q5JDN0  84 K---PDLRTGELKTLALIAYLQ-PVEQSKIIKLRGSQAYEHIKRLVEMGLVYAEP----YErTKLLGTTKKFAELYGFPE 155 Thermococcus kodakare...
O28692  79 R----EFDRGTLRTLAVIALKQ-PITLAKVAKIRGNKCYEHVKKLQERGLVKAEK----KGrSTILTTTEEFATYFGLDS 149 Archaeoglobus fulgidus
4I98_B 160 -LEELPVI 166
Q9HKK2 156 --EEFAKK 161 Thermoplasma acidophilum
Q6L0G6 151 -----DKK 153 Picrophilus torridus
Q8DKL3 157 --DHLPTI 162 Synechococcus elongatus
Q7NJH4 151 --EDVRDL 156 Gloeobacter violaceus
Q2JQ06 174 --DELAKK 179 Synechococcus sp. JA-2-3B'a(2-13)
Q0W2M2 151 --GDVESI 156 uncultured methanogenic archaeon
A0B6Q9 150 aSPEFLRG 157 Methanothrix thermoacetophila PT
Q5JDN0 156 -ND--PVL 160 Thermococcus kodakarensis KOD1
O28692 150 -AE--PEK 154 Archaeoglobus fulgidus
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