6CFW,6Z16


Conserved Protein Domain Family
MrpF_PhaF

?
pfam04066: MrpF_PhaF 
Multiple resistance and pH regulation protein F (MrpF / PhaF)
Members of the PhaF / MrpF family are predicted to be an integral membrane proteins with three transmembrane regions, involved in regulation of pH. PhaF is part of a potassium efflux system involved in pH regulation. It is also involved in symbiosis in Rhizobium meliloti. MrpF is part of a Na+/H+ antiporter complex, also involved in pH homeostasis. MrpF is thought to be an efflux system for Na+ and cholate. The Mrp system in Bacilli may also have primary energisation capacities.
Statistics
?
PSSM-Id: 486838
Aligned: 262 rows
Threshold Bit Score: 25.8127
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
6CFW_B         29 DRVVAVDTLNTLIVAIMLLLGAAYERAIYIDIAIVYALLSYVGTLVIAK 77  Pyrococcus furiosus COM1
WP_013256312   40 DRMIGLNLVSGQILALLVLLAVRGGHGIYLDVALVYDIFGFVGLLAITH 88  Sediminispirochaeta
WP_013968331   32 DRLTALAVISSLILALLVLYGTQEGRLLYLDVALLYDVFGFLGILAIAQ 80  Gracilinema caldarium
WP_014777564   28 NRILALDTLSILVIALLTLLSLFYQRSIYLDVALIFAVIGFAGVILFSR 76  Thiocystis violascens
WP_015281271   28 NRILALDALTILAIALFALLAVFFGRSIYLDVAFVFAMVGFAGVILFGR 76  Thioflavicoccus mobilis
WP_020943693   30 RRAMAQNLITSALCPALLLLSQGYARPAYVDLALLMALLAPIGTLVFAR 78  Streptomyces collinus
26_pfamImport   1 -RVVAQNMATLLLCLVFLLLAQGYGRTAYVDLALVISVLGPAGTLVFAK 48 
WP_012530113   29 ERFVALQMAQILAVLTLLLLAEGYGRDIYFDLALVLATLSFASGLVYIR 77  Citrifermentans bemidjiense
41_pfamImport   1 NRLVALQFSGIVATLIMLLLAELYGRSIYFDVPLTMAILTYANLLVYLR 49 
WP_015793429   31 DRIVALNTVCTQAALSVFFYAAYTDRSIYLDVAIWFASFSYLGAIVFAR 79  Catenulispora acidiphila
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap