1X8Z


Conserved Protein Domain Family
PMEI

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pfam04043: PMEI 
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Plant invertase/pectin methylesterase inhibitor
This domain inhibits pectin methylesterases (PMEs) and invertases through formation of a non-covalent 1:1 complex. It has been implicated in the regulation of fruit development, carbohydrate metabolism and cell wall extension. It may also be involved in inhibiting microbial pathogen PMEs. It has been observed that it is often expressed as a large inactive preprotein. It is also found at the N-termini of PMEs predicted from DNA sequences (personal obs:C Yeats), suggesting that both PMEs and their inhibitor are expressed as a single polyprotein and subsequently processed. It has two disulphide bridges and is mainly alpha-helical.
Statistics
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PSSM-Id: 397934
Aligned: 636 rows
Threshold Bit Score: 30.2081
Threshold Setting Gi: 670446081
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1X8Z_A         6 SEMSTICdKTLNPSFCLKFL--Nt--kFASpnlqaLAKTTLDSTQARAT---QT-LKKLQSiid------ggVDPrskLA 71  thale cress
XP_002314521  36 DLIAQTCkHTPYYNLCVTSLksVp--kSSGadvqgLALIMVDIVRAKAS---TA-LRFINQel--------kRSPglrRP 101 black cottonwood
KRH02397      37 KLIENTCkKTPNYNVCLESLkaSp--gSSSadvtgLAQIMVKEMKAKAN---DA-LKRIQElqr-----vgaSGPkqrRA 105 soybean
NP_001235420  37 NLIEETCkQTPHHDLCIQYLssDp--rSTEadvtgLALIMVNVIKIKAN---NA-LDKIHQllq------knPEPsqkEP 104 soybean
XP_002313933  30 NLIEKTCkQTPYYDLCVRSLisSp--rSFNtdvegLAKIMVHTINARAT---HT-LHRINKllq------hrqDTnmkRA 97  black cottonwood
EEF36859      26 NLIEKTCrKTPYYQLCISTLvsNp--hSFDadiegLAKIMVHTIDAKAT---HT-LNRINElleqsqrgsrsHDQkeqQE 99  castor bean
XP_013738720  24 NLIQQLCqKNRYEPLCVSTLnlDprskTSDlq--gLASISIDATTKKTN---ET-LTYLANcldrtg-------gdraaf 90  rape
XP_002883047  32 NLVQQLCkRNRYQALCISTLnlDprskTSNlq--gLASISLDATTKKFNvtlTYlISVLKNvtrree------------f 97  Arabidopsis lyr...
XP_002315244  26 DLIQETCqKTRYPALCVKTLksNp--rSSTadakgLVHIMLEANLANSK---LT-LATVSKllk------esSDKalkKC 93  black cottonwood
XP_015165069  24 DLIVDVCqTssnfKVCVNALraDp--qSPSadkkgLVRILLQQCLTKTK---SI-YNEVANlleq-----akehVl-iQC 91  potato
1X8Z_A        72 YR--SCV-DEYESAIG-N--------LE-----EAfehlasgdgmgmNMKVSAALDGADTCLDDVKRLrSVDssvvn--- 131 thale cress
XP_002314521 102 LR--FCA-SCYDAILTaD--------IP-----EAiealqkgdpkfaENGTNDAAVEATSCEDGFhgkspl-------tn 158 black cottonwood
KRH02397     106 LS--SCA-DKYKAVLIaD--------VP-----QAtealqkgdpkfaEDGANDAANEATYCETDFSA---AGnsplt--k 164 soybean
NP_001235420 105 LS--SCA-ARYKAIVEaD--------VA-----QAvaslqkgdpkfaEDGANDAAIEATTCENSFS----AGksplt--n 162 soybean
XP_002313933  98 LQ--SCA-SRYDAIIKeD--------IP-----ESlqalrlgnykfaEAGTVDAAFEARLCEKEFR----RCkspla--d 155 black cottonwood
EEF36859     100 LR--DCA-DRYNEILKgD--------VP-----QAmqalhkgnfrsaKERTFDAAAEAISCEEEFsgqspl-------sd 156 castor bean
XP_013738720  91 EEygTCVdQDYGASID-RylpgalanLKakkysAA------------IANLQDVMDATGDCENQFagscplp-----vsq 152 rape
XP_002883047  98 etygTCI-EEYGAAVD-RflpavvadLKakkysEA------------MSEMKDVVAKPGYCEDQFagqspl-------ta 156 Arabidopsis lyr...
XP_002315244  94 LD--VCA-EEYDTAANdD--------FP-----TAiqsleindlgtaKIHVSAAFDAPGNCRDTFSEV-PGVqappdlsk 156 black cottonwood
XP_015165069  92 LQ--ICK-ENYDLAID-D--------AT-----TAikdfdandffgaKISASAVITGPDTCEESFTEP-PIRtspik--s 151 potato
1X8Z_A       132 nsktIKNLCGIALVI 146 thale cress
XP_002314521 159 lnreVHDTSVVASAI 173 black cottonwood
KRH02397     165 qnnaMHDVAAVTAAI 179 soybean
NP_001235420 163 hnnaMHDVATITAAI 177 soybean
XP_002313933 156 mnrvVHDVSIVAASi 170 black cottonwood
EEF36859     157 mnmkVHDISVVAASi 171 castor bean
XP_013738720 153 rnkaVHDIADMTtdi 167 rape
XP_002883047 157 rnkaVHDIADMtagi 171 Arabidopsis lyrata subsp. lyrata
XP_002315244 157 lndyFEQLSVTALIm 171 black cottonwood
XP_015165069 152 ksedLMNFVDLTLSl 166 potato
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