2YZO,1VR0,2Z0J


Conserved Protein Domain Family
2-ph_phosp

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pfam04029: 2-ph_phosp 
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2-phosphosulpholactate phosphatase
Thought to catalyze 2-phosphosulpholactate = sulpholactate + phosphate. Probable magnesium cofactor. Involved in the second step of coenzyme M biosynthesis. Inhibited by vanadate in Methanococcus jannaschii. Also known as the ComB family.
Statistics
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PSSM-Id: 397923
Aligned: 131 rows
Threshold Bit Score: 154.207
Threshold Setting Gi: 313152390
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2YZO_B          11 PVec----rTAVVIDVLRATSTIVTALSNGASGVIPVKTIEEALEKKK------------EGVLICGERNAQKPKGFNLG 74  Thermotoga ma...
jgi:Anamo_1691  11 psgelehvdawIVVDVLRATTMMTAFFERGGKMILPVKEVEEAYSLKKml---------gKNWLLMGERNSLPPPCFDCG 81  Acetomicrobiu...
jgi:Deipe_0257   7 llphgdypdTVLVVDVLRATTTAGVYLERGARSLLLTASPERALELRSsgenregpsessANVLLGGERGGLPIPGFDFG 86  Deinococcus p...
jgi:Deima_2363   7 llphgaysdTVLIVDVLRATTTAITYLERGADALLLTASPERALALRGttgedg-tdvrdDRYLLGGERGGLAIPGFDFG 85  Deinococcus m...
WP_013703714     9 pRaemtfpdVVIVVDVIRATTTAVAFLEAGARTVHFTASPEAARAFRT------------RGALVAGEVGGLPPEGFDLG 76  Marinithermus...
2Z0J_G          12 HLay---pdVVLVVDVIRATTTAAAFLEAGAEALYWTPSLESALAFKD------------EDVVLAGETGGLKPPRFDLG 76  Thermus therm...
WP_013014380    12 NLsy---tdVVLVVDVIRATTTATAFLEAGAEALYLTSDVESARAFRD------------TDVVLAGEEGGLKPAGFDYG 76  Meiothermus r...
WP_013159589    18 ELlf---sdVVLVVDVIRATTTAAAFLEAGASALYLTPSIESARAFKD------------EDVILGGEVGGLKPQGFDLG 82  Meiothermus s...
jgi:Ocepr_0784  11 paealppvaTALVVDVIRATTTAAFLLAAGARELVLTAEVAQARAEARr-----------RGALLAGERGGLPPEGFDLG 79  Oceanithermus...
Q1ATL2          18 LPg-----sTAVVVDTLLATTTLLTILENGARRVFPAESLEAAAELCArl---------dGACLRGGEQGAERIEGYDLG 83  Rubrobacter x...
2YZO_B          75 NSPLEYRKE--KISGKTIVLTTTNGTQVIEKIRS--EEIIAASFLNLSAVVEYLKSKED--ILLVCAGTNGRFSLEDFLL 148 Thermotoga ma...
jgi:Anamo_1691  82 NSPFE-LSRycLETYDGAIMTTTNGTKALIYASSysNNVFIGCARNATAALKAALRCGNn-IGILCAGRHNRVMVDDTAC 159 Acetomicrobiu...
jgi:Deipe_0257  87 NSPVEADSQ--NFTGKVIVMNTTNGTGAAHVAAAtgKRVLLASLRNAHAAARRARALAVeeIAIVCAGSNGRASLEDIYT 164 Deinococcus p...
jgi:Deima_2363  86 NSPVEANSQ--NFTGRTVVMNTTNGTGAAHVAGTsgKHVLLASLRNAHAAARRAKALAVeeVAIVCAGTDGRVGMDDVYA 163 Deinococcus m...
WP_013703714    77 NSPREALAA--PVRGREVAMSTTNGTRAAILAAQtaRHVLLGSLYNAPAAARLARALAReeVAVLCAGKEGQPGLDDTYT 154 Marinithermus...
2Z0J_G          77 NSPREALSA--QVAGRVVVMSTTNGTKAAHAAARtaKHVLLASLYNAHAAARLARELATeeVAILCAGKEGRAGLDDLYT 154 Thermus therm...
WP_013014380    77 NSPREALEA--PVGGKIVVMSTTNGTRTAHLAARsaKHVLLASLFNAHAAARLAHQLATeeVAILCAGKEGRIGLDDVYT 154 Meiothermus r...
WP_013159589    83 NSPQEALEA--QVGGRTVVMSTTNGTKAAHLAARsaKHVLLASLYNAHAAARLAHELATeeVAVLCAGKEGRVGLDDTYT 160 Meiothermus s...
jgi:Ocepr_0784  80 NSPREADPE--RVRGRAVVMTTTNGTRAALRAAGaaQRVGLAALVNAGAAVRWAAAREGd-LVLVAAGREGRAALDDAYV 156 Oceanithermus...
Q1ATL2          84 PYPEEYPPG--VVSGRDVVFVTTNGTRAIADAASa-RRVLVGCPRNAPAVARHLEASGEgsVYIVCAGSGGRFTLEDFLG 160 Rubrobacter x...
2YZO_B         149 AGAIVKRLKRn----DLGDGAHAAERYFESV-ENTREEIKKHsSHAKRLISLGFENDIEFCTTEDLFKTVPA 215 Thermotoga maritima MSB8
jgi:Anamo_1691 160 AGLMVNAMKEmteriDLNDGGKIAWAIWKHyhCDLLEAFKDA-EHARRLEELGLWNDVVYASCQNKSEVVPR 230 Acetomicrobium mobile...
jgi:Deipe_0257 165 AGVLCEYLMSmg-eaGIDDGARIALTVRRNa-SDPLEALSSS-AHGVVLSRLGLGEDVRFSARPSESTLVPV 233 Deinococcus peraridil...
jgi:Deima_2363 164 AGVLAEYLMAmg-efTVDDGARIALTVRRTv-GNPLEALSSS-AHGIALDRLGLGEDVRYAAQVSESTTVPV 232 Deinococcus maricopen...
WP_013703714   155 AGVIAELLRAeg-plSPNDGAWIAFATREAy-PTPLEALRRS-AAAAALERVGLEADVPFCAQIGGSALVPV 223 Marinithermus hydroth...
2Z0J_G         155 AGVLAEYLGFlg-evEPEDGARVALAVKRAy-PDPLEALSLS-AAALALKQVGLEADVPFCAQVAKSAAVPV 223 Thermus thermophilus HB8
WP_013014380   155 AGVLAEFLQImg-syELEDGALTALTTRRAy-PDPLEPLHLS-GAAQALRQVGLEADVPFCAQIAASPAVGM 223 Meiothermus ruber
WP_013159589   161 AGVLGEFLQLmg-qyELDDGALVALSTRRTy-PDPLEPLSLS-AAAQALKQVGLEDDVPFCAQVAKSPAVPL 229 Meiothermus silvanus
jgi:Ocepr_0784 157 LGALVAGFRVlepgvRLDDGARLAQALFLAH-PEPRPLLAAS-AAAEALAAVGLAADVEACARIDALALVPE 226 Oceanithermus profund...
Q1ATL2         161 AAAIVGNMDAgs--wQLNDAAWLALDFYGRL-GDPLGVLRSG-RTGRWFAEHGRLDTLRFVAEVGASGLVPE 228 Rubrobacter xylanophi...
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