4DN9,4NPO,3BM7,1X7V,1Y0H,4NL5,4OZ5,2GO8,3FGV,3MCS,1TUV


Conserved Protein Domain Family
ABM

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pfam03992: ABM 
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Antibiotic biosynthesis monooxygenase
This domain is found in monooxygenases involved in the biosynthesis of several antibiotics by Streptomyces species. It's occurrence as a repeat in Streptomyces coelicolor SCO1909 is suggestive that the other proteins function as multimers. There is also a conserved histidine which is likely to be an active site residue.
Statistics
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PSSM-Id: 397890
Aligned: 88 rows
Threshold Bit Score: 40.3252
Threshold Setting Gi: 81554191
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4DN9_B  24 YGLIGKXR-ATPGQRDALIAI-LVEGAS----SXPGCLSYVVA--QdPKDPDAIWITEVWDS---PES-HKASLSL---- 87  Chloroflexus aurantia...
Q8XYB2  24 VVLVNLFL-LDKADEEAFLRV-WQDDANfm-kRQPGFISTQLH--RaIGDSPAYLNYAVWES---NAH-FRAAFMH---- 90  Ralstonia solanacearum
Q9FC02  15 VVLIKTYT-VPSEEADYFTEA-YQENARim-sTQPGFIRSRLHrpLaDAPETRFVHVAEWSS---GTE-LDRATGN---- 83  Streptomyces coelicolor
Q9I1K5 248 YYAVIFSS-HRSAVDDGYAEA-AERMLEla-sRQPGYLGVESV----RGANGFGITVSYWDS---EAA-IRAWSRH---- 312 Pseudomonas aeruginosa
3FGV_B  14 REVVIVKStPQRGKFNAFAEL-VGKLVSet-rDFPGCLGAYLX--L-APERNEQVVXHIWETpdaLEAyLTWRADR---- 84  Ruegeria pomeroyi DSS-3
Q9X9W3 129 VIVDIEFEgPDPDRQRAWVDA-VFEALEsephPHPGGISAHFH--LsTDGTR-VLNYAEWES---AQA-HLDALAApgdg 200 Streptomyces coelicolor
Q9CFE4   3 ITVNILYQ-GEGEKAHLFADEmVSSGLVykirQQSGNLRYEYF--VpLDNQQAILLIDEWEN---QEA-IDIHHKS---- 71  Lactococcus lactis su...
Q8CZ78  12 LTIHVYYK-GDGDSAIKFAREmLDSGLVeeirNQKGNLKYEYF--LpIEKEGTILLIDQWIN---QEA-LDEHHQS---- 80  Streptococcus pneumon...
Q7Z6G3 286 QLVRQEMA-VCPEQLSEFLDS-LRQYLRgt-tGVRNCFHITAV--R-LSDGFTFVIYEFWET---EEA-WKRHLQS---- 351 human
Q8N987 252 MLVQRQMS-VIEEDLEEFQLA-LKHYVEsa-sSQSGCLRISIQ--K-LSNESRYMIYEFWEN---SSV-WNSHLQT---- 317 human
4DN9_B  88 -----PSVQDAI 94  Chloroflexus aurantiacus J-10-fl
Q8XYB2  91 -----PEFRAKL 97  Ralstonia solanacearum
Q9FC02  84 -----QEWHAAL 90  Streptomyces coelicolor
Q9I1K5 313 -----AEHRDAQ 319 Pseudomonas aeruginosa
3FGV_B  85 -----GDFLEIN 91  Ruegeria pomeroyi DSS-3
Q9X9W3 201 vgsttPQWERVQ 212 Streptomyces coelicolor
Q9CFE4  72 -----PMMTKIA 78  Lactococcus lactis subsp. lactis
Q8CZ78  81 -----KTMQKIl 87  Streptococcus pneumoniae R6
Q7Z6G3 352 -----PLCKAFR 358 human
Q8N987 318 -----NYSKTFQ 324 human
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