Ecotin is a broad range serine protease inhibitor, which forms homodimers. The C-terminal region contains the dimerization motif. Interestingly, the binding sites show a fluidity of protein contacts binding sites show a fluidity of protein contacts derived from ecotin's innate flexibility in fitting itself to proteases while.
Jiyao W et al.(2023). "The conserved domain database in 2023.",