5BNZ,5ZDK,4R3Z


Conserved Protein Domain Family
tRNA-synt_1c_C

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pfam03950: tRNA-synt_1c_C 
tRNA synthetases class I (E and Q), anti-codon binding domain
Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only glutamyl and glutaminyl tRNA synthetases. In some organisms, a single glutamyl-tRNA synthetase aminoacylates both tRNA(Glu) and tRNA(Gln).
Statistics
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PSSM-Id: 397855
Aligned: 111 rows
Threshold Bit Score: 92.3336
Threshold Setting Gi: 67461768
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5BNZ_A 349 APRAMCVLKPLKVV-ITnypEG---QVENLELPRHPK-EDMGVRVLPFG--R---ELFIDAGDFeevppagyKRLIPGGE 418
Q6L0N9 403 AMRFFFVNDPVLLD-LN----Nd--IDLESHARYHPD-IDLGYRKYIIKshS---RIYLSRRDL--------DDIKPDEI 463 Picrophilus torridus ...
Q979Q0 402 AYRFSFTKDPVEIK-ME----Gs--NGLTARLPYHPShPEYGVRKYEIG--D---TVYISKGDA--------DKIADGER 461 Thermoplasma volcaniu...
Q3IPL2 419 ADRRFFVRDGVEKP-LA---GG---P-ESASPPLHPNdEDRGRREIPVG--D---AVYVEPDDV--------PADG--ER 475 Natronomonas pharaoni...
Q18GA5 424 ADRYFFVRNGETFT-LE----TaseDTIAGHPPLHPDnPERGERVVPVT--D---GITIEPADV--------PADG--DR 483 Haloquadratum walsbyi...
A8ABI5 404 AYRVMAVEDPAPAK-LL----Ap-eP-LEAELPWHPT-EGLGSRKYSVE--Pg-eVVYLERADL--------RRAKRRGG 464 Ignicoccus hospitalis...
Q8ZU33 411 ADRYMYVADPVKLV-FE----Ad--KELTAHVPFHPSfKERGERTYRLG--PgrvEVYIQRRDA--------VAG---KV 470 Pyrobaculum aerophilu...
Q704D8 212 ADRYMFVPEPVKLV-IN----Lp--KRIVAKIPVHPSfPERGHREYELG--PgevSLYISRKD---------AEL---GS 270 Thermoproteus tenax
A3DMR5 398 AKRYMAIEEALPLKlIG----Fn--NSIEAHVLRHPStRETYNYIIKPG--D---IVYISQKDF--------NIIQN-KM 457 Staphylothermus marin...
A2BK91 404 AKRIMAALSPVPVE-VE---GLpwrE-KEFRIPFHPSg-QLGERIVKLA--GpkaTIYVSQSDA--------VQLAKGNI 467 Hyperthermus butylicu...
5BNZ_A 419 VRLRGSYVIRADEAikdaDGNIVE--LRCSYDPDTLGKNpegRKVKG-VIHWVPA---EGSVECevrlydrlfrsanpek 492
Q6L0N9 464 FRLKDLCVVKRTED----G---------IAYIDDDS-------NKRLkIIQWCPE---N-SHEF---------------- 503 Picrophilus torridus ...
Q979Q0 462 FRLKDLCYVVRKGD----R---------FLFDGTEM-------KEKTkIINWCPP---N-SREF---------------- 501 Thermoplasma volcaniu...
Q3IPL2 476 VWLKGLGPVRHEDG----A---------FVATDDDIEVV---RDGAVdVVHWVPA---QESVPL---------------- 520 Natronomonas pharaoni...
Q18GA5 484 VWLKGYACVRRDDN-------------HFRTTNDGIEVV---REGDVdVIHWAPApesSASISV---------------- 531 Haloquadratum walsbyi...
A8ABI5 465 LRLMELANFKYKGF----DEDEGV----YLLEFESKELD---KEKGYdIVQWVK-----DPKGA---------------- 512 Ignicoccus hospitalis...
Q8ZU33 471 VRLMELANVEIVRV----EGDVAY----GRIHSYSLDEA---KKIGApIIQWVW-----DPVEI---------------- 518 Pyrobaculum aerophilu...
Q704D8 271 FRLMELANVVVRRK----EGDVYY----GEVVGYTIDEA---REAKMpIIQWTPD----NSREA---------------- 319 Thermoproteus tenax
A3DMR5 458 FRLMGIGNFALTRP----VFSKNYigFEARLISLSAKEA---KQYRApIIQWVKL---EQSIRV---------------- 511 Staphylothermus marin...
A2BK91 468 VRLMEAFNIEVLGA----SPRRVR----ARYHSLTVDEA---RQHNApIIQWVPA---TDNIAV---------------- 517 Hyperthermus butylicu...
5BNZ_A 493 aeeggsFLdnINADSLQVLa--GCRAEPSLGQANPEDRFQFEREGYFVAD 540
Q6L0N9 504 ------TV--QKPDGTVd----SGMLEPLAYNYN--GVSQFERYGYVNII 539 Picrophilus torridus DSM 9790
Q979Q0 502 ------QV--LKPDGSId----KGLIEPASKGYR--GISQLERYGYVNFY 537 Thermoplasma volcanium GSS1
Q3IPL2 521 ------RL--RTVDGDe-----AGHAEPGIETYDADDIVQFERIGFARID 557 Natronomonas pharaonis DSM 2160
Q18GA5 532 ------RM--RTPDGDi-----TGIAEPDLTDAEIDDIVQFERVGFARID 568 Haloquadratum walsbyi DSM 16790
A8ABI5 513 ------IV--WRPGERK------SFALVEPEALKLEGWVQLIRKGYAKVD 548 Ignicoccus hospitalis KIN4/I
Q8ZU33 519 ------TV--IKPAGVGRKeveVGLGEGWLERVEVGKYVQFFRYGYLKKR 560 Pyrobaculum aerophilum str. IM2
Q704D8 320 ------VV--IRPVAAGKKaveRGLIEPGAETLREGDIVQFLRYGFVKLA 361 Thermoproteus tenax
A3DMR5 512 ------KL--IIPKETN-LetrILLAEKALTNEELGNIVQFYRIGFARID 552 Staphylothermus marinus F1
A2BK91 518 ------EV--LKPEGLD-LvqeRGLAEPAAAQLKPGEIIQLVRIGFARVD 558 Hyperthermus butylicus DSM 5456
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