1JN5,4WP2


Conserved Protein Domain Family
TAP_C
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pfam03943: TAP_C (This model is not part of the current CDD release)
TAP C-terminal domain
The vertebrate Tap protein is a member of the NXF family of shuttling transport receptors for nuclear export of mRNA. Tap has a modular structure, and its most C-terminal domain is important for binding to FG repeat-containing nuclear pore proteins (FG-nucleoporins) and is sufficient to mediate nuclear shuttling. The structure of the C-terminal domain is composed of four helices. The structure is related to the UBA domain.
Links
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Statistics
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PSSM-Id: 515914
Aligned: 132 rows
Threshold Bit Score: 56.4123
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1JN5_B       200 EMLQAFSTQSGMNLEWSQKCLQDNNWDYTRSAQAFTHLKAKGEIPEVAF 248 human
XP_002668744 116 ELVLYLMNRTNLVHVFAYDCLQQYQWNINSALQRVFELASMNRLPSHAF 164
XP_003675478 534 ELLNRLHLQTKLNAEYTFMLAEQSGWNYDVALKAFQSSVTN--LPREAF 580
XP_003685214 525 ELLNKLHVDTKLNSEYTYMLAEQSGWNYDVAFKGFQSSMGQ--IPREAY 571
XP_002171475 563 ELVARVKAETGLNDVFAEMCCQQNNWDYNRAIAAFTELKQRGVIPPEAF 611
Q9Y8G3       547 QIVLKIKAETGLNDYYAHMCCEQNNWDYNSALASFLELKSRNVIPAEAF 595 Schizosaccharomyces pombe 972h-
CCG82111     565 GMINQLKTATGLNTNYANMCLSQLQWDYQAALKVTQDLKSKNGLPAEAF 613
XP_001732457 430 amSLQLSAQTSLSYPFAVQCLGENDWNMTRALSVFTSLQAAGTIPPEAF 478
XP_011387665 613 amSLQLAAQTGLIYPFAVQCLQENGWDYNLALANFQTLKASNAIPPQAF 661
KDE09703     551 mTVLQLQSVTNLTYSFAYMCLEQNAWVPETALANFQQLHASGAIPAEAF 599
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