4CLC


Conserved Protein Domain Family
Haem_degrading

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pfam03928: Haem_degrading 
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Haem-degrading
Haem_bdg is a bacterial protein that is up-regulated in response to haemin- and peroxide-based oxidative stress. It interacts with the SenS/SenR two-component signal transduction system. Iron binds to surface-exposed lysine residues of an octomeric assembly of the protein.
Statistics
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PSSM-Id: 397835
Aligned: 531 rows
Threshold Bit Score: 47.873
Threshold Setting Gi: 494963057
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4CLC_B              34 FTYQDAFDLGTYIKNAVKeNf---pDKPVAIDI-SLPNGHCLFRTVTYgGS-ALDNDFWIQRKKKTALRFGHSSFYMGCK 108 baker's y...
jgi:AciPR4_1055     23 FNLEIAWQLGERARSLSVeR-----GYKLAIEV-RR-GPATVFLTAMD-GT-TPSSVDWLRRKANTCAWFARSTYSTGLQ 93  Terriglob...
EDS19513            10 FDNEDAFLLGCNLVEKVKkEnlkniRIRIVLNQ------DIVFQYLMN-GK---KGDQWLNRKQNTVELFKLPTYQIWQE 79  Erysipela...
CCY42029            25 FSHRDAWELGHALVDACEkM-----GAPLAVEI-EI-NHVIVFRYYPD-GT-GAYHEQWLRRKRNLVNLLEKSSQRAYYE 95  Firmicute...
sklacau:PSAB_02990  20 FSAEDAFTLGMNVLEIAGeQ-----SNSLVVSV-RR-NGKLLFYKAGP-DT-VIDQDDRIRRKTNAVNLKGRSSLYLFLK 90  Paenibaci...
Q88S33              20 FNLDDVDKLVISLKKIGReN-----FDKVCILI-KI-NKRIVFFHAGT-QT-TNENNLWIHKKANVVDKFDHSSLFE--K 88  Lactobaci...
jgi:Cfla_2865       23 FTQDDAVDLGLLAVAVVReR-----G--ANLAVrVELGGATVFLAMT--GStGAGNVPWLEGKAAVVHRFGEASLLVRRR 93  Cellulomo...
CDC04470            20 FSNDDAFALGCLLVKHRKk------FGPAAVEV-SI-NGLALFRNF-PnGT-NQENGVWLAAKRNLVNARGRSSYGSFLE 89  Clostridi...
WP_107029051        18 FNNHDAYQLGQIIVDHIEkNhlknvRIRIVLDK------DIVFQYLMD-GK---KGVIWLDRKQKTVEKYGHSSYYIYLE 87  Faecaliba...
CDD59801            26 FTRKQALELGLLIAEVTEkKyygsvAVRIVEDE------TTVFAYKME-GA-TLEADWWMTNKLAASRLTGMSSLRALTA 97  Clostridi...
4CLC_B             109 kgdktpeek----ffvdskeyaFHGGAVLIQSERstyPYACLTISGLKQEEDHLMAVS 162 baker's yeast
jgi:AciPR4_1055     94 laqksqtlar---haladrdyaADGGSVPLMVKDa-gLVGSLTISGLDQRADHELAIE 147 Terriglobus saanensis SP1PR4
EDS19513            80 nershcyqq-----ytnderyvICGGAYPIIVGKg--MIGSVIVSGLAHNEDHQIIvd 130 Erysipelatoclostridium ramosum ...
CCY42029            96 levncedqer--dwrlprsdyaACSGAFPIRIRGg-sVIGVAAVSGLPDPGDQTALLN 150 Firmicutes bacterium CAG:124
sklacau:PSAB_02990  91 yegdeqafcq--ansvkaedyaLYGGCFPIKLRNk-gMIGTVAVSGLTAEEEHMLCLN 145 Paenibacillus sabinae T27
Q88S33              89 aiyeenpdkfyinnglsrrdyaIVGGGFPIGLESt-gIIGSLIVSGLTDTEDHDLAYQ 145 Lactobacillus plantarum WCFS1
jgi:Cfla_2865       94 heaagtpfee--rtdvdhdtvkAHGGAVPLRVGGe--VVGTLTTSGEPDVVDHSVAVE 147 Cellulomonas flavigena DSM 20109
CDC04470            90 aqeqgktltd--wkmlpeteyaLCGGGFPIRLKNg-aLIGTACVSGLPHELDHQTLVD 144 Clostridium leptum CAG:27
WP_107029051        88 neengtyqe-----dekdeslvICGGGFPLIIRGe--LRGSILVSGLIHDEDHQVIvd 138 Faecalibacillus intestinalis
CDD59801            98 srareleas----wkvreenffVCGGCIPVFMRDgsrPFAYVMVSGMEHWNDHQVIAD 151 Clostridium sp. CAG:43
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