Conserved Protein Domain Family
NrfD

?
pfam03916: NrfD 
Polysulphide reductase, NrfD
NrfD is an integral transmembrane protein with loops in both the periplasm and the cytoplasm. NrfD is thought to participate in the transfer of electrons, from the quinone pool into the terminal components of the Nrf pathway.
Statistics
?
PSSM-Id: 397824
Aligned: 13 rows
Threshold Bit Score: 137.923
Threshold Setting Gi: 74576685
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
P45014         6 PVPFHTPNL---VWDYTIAI-YLFLL--GISSG--AVQLAIAY----KRSNKL--ENL--SQN---WI-IRSGVIL-GSV 64  Haemophilus inf...
P31077         6 GSIEQYNTV---VWHWPIAV-YLFLA--GLSAG--AIISAIII----KWMKGN--ESS--PWD---GI-IKAGALI-APL 64  Wolinella succi...
Q97XY0        39 TEPND-EPI---PWGLLVIG-YMFFG--VIGTG--VSTYNSLY----ELFNKNhpEKN--PFK---NIsLRNEWI---AL 97  Saccharolobus s...
WP_012970475  43 WVSGMNNSV---VWGTPHVF-AVFLI--IAASG--ALNIASIG----TVFKKP--IYK--PLG---RL---SGLL---AV 97  Allochromatium ...
O29750        40 GLNGLSNRV---PWGIVNAG-IPYFI--GLSAG--SLIVSALA----GVFNIK--KYK--VFS---RI----AAYM-AAA 95  Archaeoglobus f...
BAL96714      48 VVTGMSDQV---SWGFYIAN-FAFLV--GIAAA--AVLLVIPA----YLFHR-----G--DVK---QV-VIFGEAL-AVA 103 Rubrivivax gela...
O30063        30 iVTNMRNPF---SWGLYIAM-WAFFV--GTAAGglVVSSAIYI------FGAR--EFK--PIA---PV-ASTTAFI---F 86  Archaeoglobus f...
Q9HR72        45 GLIETGMRN---VFSWGLYI-MLFVLfvGLSAG--GLILSSAP----KFFHSQ--R-----YE---GF-ARLGVLV-SLG 102 Halobacterium s...
O30284         4 LNPQHYYLLqqpWWGILIAF-YLFLG--GLGAM--AFCISFYF----WRQKGS--QS----------L-VVGGSLL-GLI 60  Archaeoglobus f...
Q9Y8M5        24 D--FKAGGA---IWGVLLVV-YPLMT--GILAGs-YLVSALAYgfgvKRLYRV--AGL--S-----LI-ISVGLLLsAPI 84  Aeropyrum pernix
P32709         4 TSAFHFESL---VWDWPIAI-YLFLI--GISAG--LVTLAVLL----RRFYPQ--AGG--ADS---TL-LRTTLIV-GPG 62  Escherichia col...
Q9CPL1         2 NSPFHFPSL---VWDHTIAV-YLFLL--GISAG--ATMLAVLL----KRA-GL--AGAepSNN---HV-IRCTAFL-APL 61  Pasteurella mul...
Q9Z4S7         9 EVLAHPQDI---SW-LPWAVqYFFFI--GIAAC--AALFACYL----HWRKKD--AAT--EENralLI-AITCAIT-APL 70  Salmonella ente...
P45014        65 PTL-I-GLTLLIFHLT-RPW-TFWKLM-F--NYQF--N---SVMS--M-GV--MLFQ--IYMLFLV---IWGVVIFKK-- 120 Haemophilus inf...
P31077        65 TIG-A-GLLLLIFDLT-RPL-HFWKLL-I--FYNF--S---SVMT--L-GV--LALF--AYFPVVL---IFLLGVFKK-- 120 Wolinella succi...
Q97XY0        98 TVL-I-PGWIMVFASTyKPG-E--AVY-I--YTSFrdT---SRIA--WnGL--LYAL--VGIGIIL---EILALIGEKrr 157 Saccharolobus s...
WP_012970475  98 AML-MgGLLVLVMDLG-RPE-RLIVAM-T--NYNF--S---SIFA--W-NI--FLYT--GFMAIVI---AYLWSMADR-- 154 Allochromatium ...
O29750        96 WII-A-AILSIALDIG-KLY-HFMNAV-R--YFNP--T---SIFS--W-NA--FLYS--SYFVICS---IYLLVQFE--- 150 Archaeoglobus f...
BAL96714     104 AVV-A-AMLFVTVDIG-RPE-RIWHMLpV--VGRF--N---WPLS--M-------LA--WDVVVLV---GYL-------- 150 Rubrivivax gela...
O30063        87 AVG-A--MVMVLPDLG-RVD-RILNMF-L--YPNF--S---SLLP--W-DL--IVLS--TYAFLSA---IYTYVLLMP-- 141 Archaeoglobus f...
Q9HR72       103 CIIvA-GLLIL-PDIG-RPD-RIYQFV-T--SPDF--R---SPMVwdF-GI--VMLY--GALNVWY---LWLLT--RR-- 158 Halobacterium s...
O30284        61 AVL-I-GTLFLILDLG-HPE-RFYLVL-LspRLNP--S---SWIV--I-GS--TLLS--AFMLFAA---LFVAPM----- 115 Archaeoglobus f...
Q9Y8M5        85 FPM-A--------DLK-QPQrAFEIFL-R--PHVI--P---SDAY--P-GVspMAFFgiLYIPLLVvalLNLIFVYRA-- 141 Aeropyrum pernix
P32709        63 AVI-L-GLLILVFHLT-RPW-TFWKLM-F--HYSF--T---SVMS--M-GV--MLFQ--LYMVVLV---LWLAKIFEH-- 118 Escherichia col...
Q9CPL1        62 SLI-I-GLVILIFHLT-KPW-TFWYLM-F--NYST--T---SIMS--M-GV--MLFQ--AYMLFLL---VWLAIIFHQ-- 117 Pasteurella mul...
Q9Z4S7        71 ALT-A-DL-----HQTaRVW-HF---------YAW--PtpwSWMP--W-GA--LFLP--LFTGFLA---LW--------- 112 Salmonella ente...
P45014       121 EIEALInr---fiPk----------LQ-FVMK----LIGI---A-----------ERIVS--PVEVIL-FILAAVLGAYT 165 Haemophilus inf...
P31077       121 ELCDEG-------P-----------FG-FLAP----LANI---A-----------YSMAR--PLEIVT-FVLAIGVGAYT 160 Wolinella succi...
Q97XY0       158 EYKDPIsr---llAw----------LS-SKSV----LILI---V------------------GYAILMeLILDANLGSVF 198 Saccharolobus s...
WP_012970475 155 QGGPFNy------P-----------IG-ILAL----VWRL---A---------------------------LTTGTGSIF 182 Allochromatium ...
O29750       151 --EMEK-------------------------------------A-----------TRFMA--GLAVFW----AVLVHSGT 174 Archaeoglobus f...
BAL96714     151 -LLNLGl------Pa----------YV-LHAR----WRGE---E-----------PVTARyfPVVIVA-IFWAVSIHTVT 193 Rubrivivax gela...
O30063       142 RIAERGv------------------LG-FLKKdatdLESLrqkS-----------EKYAK--VLAPIA-LPFAILIHTVT 188 Archaeoglobus f...
Q9HR72       159 DLAARGsrlslwvSdsaagrdrdrtLM-FWTA----VCAL---P-----------AAVA----LHSVTgWIFATQVG--R 213 Halobacterium s...
O30284       116 -LRWFKw-----vP---------------WAK-----------S-----------EAAIR--AFGWLA-FITGIGVAAYT 149 Archaeoglobus f...
Q9Y8M5       142 DMAAKA-------Ea----------TGnIIYR----IVSL---GrgysredverdRRVVK--ILSIIG-VILAILFHGYF 194 Aeropyrum pernix
P32709       119 DLLALQqr---wlPk----------LG-IVQK----VLSL---L-----------TPVHR--GLETLM-LVLAVLLGAYT 163 Escherichia col...
Q9CPL1       118 LVATLIeqy--akP-----------LR-FVNK----LIAF---A-----------AKFTG--LIEIIL-IILSVLLGAYT 162 Pasteurella mul...
Q9Z4S7       113 -FLAQQ-----------------------IKR----LFNK---S-----------YNVTK--WLALAS-ALCAVGLLIYT 147 Salmonella ente...
P45014       166 GFLLSALISYPMLNNPVLPA-LFLASGTSSG---IAA-TFLIILI-AGKLKG-DSH-ESHFIHKFEVPI-MVT--ELGLI 234 Haemophilus inf...
P31077       161 GFLLSAMYSYPLLNTPILPL-LFLASGISAG---ISG-NLLIGLL-FFGKST-KGE-NVGYLHGLDFKV-ILF--EAFLL 229 Wolinella succi...
Q97XY0       199 GYLSTWVYEF----GPFMSM-LFVILSFYSG---IAMlSFMTPLYnRFRKVK-EDP-NSLSIH--EMYK-ILG--RDGVL 263 Saccharolobus s...
WP_012970475 183 GFLV-ARQAY---DAAILGP-MFVALSFAYG---LAV-FMLV--L-MFGFEE-EGR-PIG-------PR-MMR--RLRNL 238 Allochromatium ...
O29750       175 GAIYSFVYSKELYHSALTPP-MFIVCAITSG---L-G-LLLANLY-FTFRFT-KRElDPKLIRGL-----ALI--FAGLM 239 Archaeoglobus f...
BAL96714     194 AFLFSANAGRPLWHSALLAP-RFIASAFASGpalIIV-ALLALRR-WGGLAV-KQT-VIDLL-----AV-VMT--VALQI 260 Rubrivivax gela...
O30063       189 AWVLATQLSRPWWYGGLLAP-TFIAAAIATG---PAV-VILASLF-VYGYED-RLK-NA---YRLLGKIsAAS--SAALL 255 Archaeoglobus f...
Q9HR72       214 GDWFSPL---------VAPV--FIAKALVSG---LGL-LLVVSIL-ADRFTA-FTA-DRGELTSLGKLL-GIF--LAFHV 272 Halobacterium s...
O30284       150 GILIGIVFNIPFWNAPALPV-IFMISALSTG---LAS-LILLMLV-VDR----EAH-EIHVMAKTDGFV-MIF--ELIVL 215 Archaeoglobus f...
Q9Y8M5       195 DILLASIKSRILWVDPSLPI-RLLASAVFSG---AAL-VTVAYYI-AARFSPgESI-DAGTMKTLSLIM-LFG--LAAAL 264 Aeropyrum pernix
P32709       164 GFLLSALKSYPFLNNPILPV-LFLFSGISSG---AAV-ALIAMAI-RQRSNP-HST-EAQFVHRMEIPV-VWG--EIFLL 232 Escherichia col...
Q9CPL1       163 GFLLSALISYPMLNNPVLPI-LFLASGTSSG---IAA-LIFCTLL-FTKEDT-HSP-ALGFLHKFELPV-VLM--EIFLL 231 Pasteurella mul...
Q9Z4S7       148 GREVSVVLARPIWFSYAFPVaMFL-----SA---LQA-FFALMIV-AARR-------DSVRLPKILWGQ-IWTlaALGLV 209 Salmonella ente...
P45014       235 V------C----FFV-G--LHF-------GGGQK--TVALHN---A----------LSG-FW---G------VVFWVGVL 269 Haemophilus inf...
P31077       230 F------I----LFV-G--MYY-------QGGST--AEVAKA---A----------LTTgGL---A------SLFWLGVA 265 Wolinella succi...
Q97XY0       264 A------T----IAV-G--FSLlwwlwltATNQQ--TSAWAE---L----------MISgPY---S------VVFLIGGV 306 Saccharolobus s...
WP_012970475 239 L------A----LFI-GiaLYF-------TLVYH--LTNLYM---AkndslehwllLSGgIY---T------FLFWVGWI 286 Allochromatium ...
O29750       240 M------V----LGY-F--LAV-------EGLEKgyIPALHE---A----------VQFvFL---TptsgvfWSFWLLV- 282 Archaeoglobus f...
BAL96714     261 S------L----FFV-G--VEL-------FTDFY--NETTHA---A----------SMR-------------YLF-FGLA 291 Rubrivivax gela...
O30063       256 F------MyyndFLV-R--YWW-------GEGLE--YEALAI---V----------FRD-YL---H------IHF-LEVL 293 Archaeoglobus f...
Q9HR72       273 V------Y----L------LAA-------ERLPH--AWAHHFgfwA----------ITSnFLigdT------VYFWL-WT 310 Halobacterium s...
O30284       216 S------I----FLL-I--RSY-------GPVAA--IESVNT---V----------LFG-WL---A------PYFVGGVL 250 Archaeoglobus f...
Q9Y8M5       265 IteitseI----LRV-G--YYL-------LPGEG--IEYYES--------------LRG-------------SMF-IDNA 300 Aeropyrum pernix
P32709       233 V------A----FFV-G--LAL-------GDDGK--VRALVA---A----------LGGgFW---T------WWFWLGVA 268 Escherichia col...
Q9CPL1       232 A------A----FFI-G--LYL-------GGGQK--TVAFET---A----------LLGgFW---A------HVFWIGVV 267 Pasteurella mul...
Q9Z4S7       210 V------A----MWVsG--DTL-------SGTAI--RQWITV---A----------LSA-------------KYYAVGWV 242 Salmonella ente...
P45014       270 IIGILIPLIAN-M--FVNDrLKYNRNFI-ILVSIFDLIGVFCLRFFILYAGQLT-VA 321 Haemophilus influenzae Rd KW20
P31077       266 GMGLALPVVLN-V--ALPHgIKHSSGFV-MLNALIVLAGVMALRFYILYAGQTF-VG 317 Wolinella succinogenes DSM 1740
Q97XY0       307 LVGVIIPIILY-G--LVYK--RGSSHML-VTSSIFTLLGMFSI---------IT-IA 347 Saccharolobus solfataricus
WP_012970475 287 LVGSLAPMWI--L--YHPV-LSQKREWI-IGACTLVIVGGFSAMYVIIIGSQAFpIA 337 Allochromatium vinosum
O29750       283 IFGIAIPII---I--VLNPkTGYDLRWI-TFAGILHAALVFAERFYLIIPGQVF-PE 332 Archaeoglobus fulgidus DSM 4304
BAL96714     292 GAG-----KLQ-P--WIWTaLALNVVAV-VILSIHPLR--RTPRLLVLACGLVF-LG 336 Rubrivivax gelatinosus IL144
O30063       294 FI-LFSAIVLA-K--ATTR------ARL-IIGSVSVNVGVLLHRFLLMPPAYNV-FA 338 Archaeoglobus fulgidus
Q9HR72       311 GLGGAVPLLL--L--ATPS-LRRRTAVI-FTASVLAVFGTLFEGIRLVFTGYQR-VN 360 Halobacterium salinarum NRC-1
O30284       251 LMGLAIPIMLI-FgyEVKR---PGVTAVtVISAIFVLVGGALLRYVVLEAGILQ-IP 302 Archaeoglobus fulgidus
Q9Y8M5       301 YYILALILLVS-L--LIPR-VRENIHSV---AAIAALA---------------I-VA 334 Aeropyrum pernix
P32709       269 GLGLIVPMLLK-P--WVNR--SSGIPAV-LAACGASLVGVLMLRFFILYAGQLT-VA 318 Escherichia coli K-12
Q9CPL1       268 GIGLVLPLLLNgI--ATPQ-LKHRKGFM-LLVACLGLIGVLCLRFFILYAGQMT-LA 319 Pasteurella multocida
Q9Z4S7       243 ALWVCTLLFCS-L--ALRHpLSQLRRVL-LVLSALALCWLM--RWTLLIQVQ-T-VP 291 Salmonella enterica subsp. enterica se...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap