1MWQ,1S7I,4LBH


Conserved Protein Domain Family
YCII

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pfam03795: YCII 
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YCII-related domain
The majority of proteins in this family consist of a single copy of this domain, though it is also found as a repeat. A strongly conserved histidine and a aspartate suggest that the domain has an enzymatic function. This family also now includes the family formerly known as the DGPF domain (COG3795). Although its function is unknown it is found fused to a sigma-70 factor family domain in CC_1329. Suggesting that this domain plays a role in transcription initiation (Bateman A per. obs.). This domain is named after the most conserved motif in the alignment.
Statistics
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PSSM-Id: 397734
Aligned: 26 rows
Threshold Bit Score: 67.3827
Threshold Setting Gi: 81779806
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1MWQ_A   5 YYVIFAQDIPNTL----EKRLAVREQHLARLKQLQAEnrLLTAGPNPAIDDENPSeagftGSTVIAQFENLQAAKDWAAQ 80  Haemophilus influenzae
Q9AJZ7   2 EFLCYHRDRPASL----SLRYELGEAHWSYMDQYAKE--MIARGPTLADDGETLT-----GSVHILDLPDPAAARTFAFD 70  Streptomyces coelicolor
Q0K0V2   2 PYLIETVDKPNHQ----HVRQATRASHLDYLE--ANKdlLLACGAKLNDDGSDAG-----GGIYIVDVDTRDAAQQFIDA 70  Cupriavidus necator H16
Q9HZ38   2 LYAIIARDIPASQ----ERRLASRPAHLARLEQLKEEgrLVLAGPHPAIDSNDPGaagftGSLIVAEFDSLAAAQSWAEA 77  Pseudomonas aeruginosa
P0AB55   2 LYVIYAQDKADSL----EKRLSVRPAHLARLQLLHDEgrLLTAGPMPAVDSNDPGaagftGSTVIAEFESLEAAQAWADA 77  Escherichia coli K-12
Q9KRE0   2 WYVIFAQDVENSL----EKRLSVRPKHLERLQQLQDEgrLLTAGPMPAIDSENPGqagftGSTVIAEFASLVEAQAWADA 77  Vibrio cholerae
P73587   3 KYVLWGTYCDNVE----EKRAPHRQAHLDGLKVQKESgvLVTIGPTKDLR----------QVFAIYDAPDQDTVEKLVQG 68  Synechocystis sp. PCC...
Q983T6 166 FHCRLIPPRPDFAftltDAERGLMKQHSDYLRDRLGDggVILFGPVADPAGPW--------GLGIVGADDEAGVRALTEG 237 Mesorhizobium loti
Q9AC00   3 LFAILCKDKPGAL----DTRLATRPTHLDYLN--QSTglKLA-GALLGDDGNPI------GSLLIVEAEDLAAAQAQADN 69  Caulobacter vibrioides
Q16CW5   2 LVALIAHDKPGAL----PIRQENRPAHVEYLKSSTAVqqA---GPLLDDAGEMC------GSLIILDVADMDEAKAWAQG 68  Roseobacter denitrifi...
1MWQ_A  81 DPYVEAGVYADVIVKPFK 98  Haemophilus influenzae
Q9AJZ7  71 EPNYQAGAYRDVLLRRWR 88  Streptomyces coelicolor
Q0K0V2  71 DPFTEAGLFAEVRIVRWR 88  Cupriavidus necator H16
Q9HZ38  78 DPYRAAGVYAEVVVKPFK 95  Pseudomonas aeruginosa
P0AB55  78 DPYVAAGVYEHVSVKPFK 95  Escherichia coli K-12
Q9KRE0  78 DPYVAAGVYANVIVKPFK 95  Vibrio cholerae
P73587  69 DPYWQNGIWTEYEVKEWI 86  Synechocystis sp. PCC 6803
Q983T6 238 DPTIRSGLGFRYEILPMI 255 Mesorhizobium loti
Q9AC00  70 DPFTTAGVFESVEVRPWR 87  Caulobacter vibrioides
Q16CW5  69 DPYGAAGLFASVDLIPWN 86  Roseobacter denitrificans OCh 114
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