3M9G,3M9G,3M9G,2KUF,2KUD,2MGV,1PMD,1PMD,7O4B,7O4B


Conserved Protein Domain Family
PASTA
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pfam03793: PASTA (This model is not part of the current CDD release)
PASTA domain
This domain is found at the C termini of several Penicillin-binding proteins and bacterial serine/threonine kinases. It binds the beta-lactam stem, which implicates it in sensing D-alanyl-D-alanine - the PBP transpeptidase substrate. It is a small globular fold consisting of 3 beta-sheets and an alpha-helix. The name PASTA is derived from PBP and Serine/Threonine kinase Associated domain.
Links
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Statistics
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PSSM-Id: 515809
Aligned: 241 rows
Threshold Bit Score: 27.6243
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3M9G_A          5 PDVIgkSVKEAEQIFNKNNLKLGKI-SRSYSDKYPENE-IIKTTPNTG-ERVERGDSVDVVISK 65  Staphylococcus aureus subsp. a...
Q75Y81        639 PSIKdiSPGDLAEALRRNIVQPIVV-GT--------GTkIKESSVEEG-ANLTPNQQVLILSDK 692 Streptococcus pneumoniae
WP_011837420  651 GLKHqiSPGGLADELRRNLVQPIVL-GT--------GGkIKKVSVKEG-KNLKANQQVLILSDD 704 Streptococcus sanguinis
WP_020999023  641 PSAKntSPGDLADELRRNLVQPIVL-GT--------GKnIKKISVKTD-EVLKSNQQILILTDD 694 Streptococcus
17_pfamImport   4 EKGKdkSPGSYAEELRRNLVQPIIL-GT--------GSsITKLSVEAG-KNVASNQQVLLLTDE 57 
O07667        621 ADYRnlSADVAAADAQKSGLQPIVV-GD--------GKkVKKQSTANG-DQLISGEKLILYTGG 674 Enterococcus hirae
O07106        631 ADYKnmTPAEALANAKVNGVDPVII-GD--------GEkIKKQSTPSG-EKLMPNQKLILITNG 684 Enterococcus faecalis
Q8XJL8        520 PDVSgkSVEEAKSILANAGVGVNPVkGEAAKSEGEAGK-VYSQS-QSGsLTIKQGEKVTITINY 581 Clostridium perfringens str. 13
1PMD_A        564 PSVKdiSPGDLAEELRRNLVQPIVV-GTGT-------K-IKNSSAEEG-KNLAPNQQVLILSDK 617 Streptococcus pneumoniae
7O4B_AAA      540 PDVEgqDKQKAIDNVSAKSLEPVTI-GSGT-------Q-IKAQSIKAG-NKVLPHSKVLLLTDG 593 Staphylococcus aureus subsp. a...
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