Conserved Protein Domain Family
YicC-like_N
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pfam03755: YicC-like_N (This model is not part of the current CDD release)
Endoribonuclease YicC-like, N-terminal region
This domain is found at the N-terminal end of Endoribonuclease YicC from Escherichia coli and similar bacterial sequences. YicC, which is important for cells in the stationary phase, and essential for growth at high temperatures, contributes to degradation of the small RNA (sRNA) RhyB via collaboration with the exoribonuclease PNPase and seems to generate a 3'-OH and a 5'-phosphate group.
Links
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Statistics
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PSSM-Id: 515783
Aligned: 506 rows
Threshold Bit Score: 84.191
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
jgi:Isop_1879   3 TSMTGFGE---ARGVlAL-GNARIELRAVNNRHLKVTMKLPPPLETIEPELDRLVRSMVKRGTLTVSVRlDRPK--T-AE 75 
WP_231865047    2 TGFGLGDA---SLTDgr-vvAEIRSVNQRFLDVRARLPRELVDLTMFAEQVARERLRRGRIEIIVRTEGaVLAP----ST 73  Sorangium cell...
WP_290587266    2 TGFGKSEA---TLPNrKI-SVEIRSLNSKQLDLGMRLPAIYRQSEYEIRNIVARTLLRGKVDLFVTVESqA--VetS-AH 74  Alistipes sp. ...
WP_015416516    3 vSMTGFGR---CETN-DDaWTHVWEIKSVNGRFLDVKWRMPSSLRGLENGWEKIVRTYASRGRVDISLNlEVLDagI-LG 77  Pseudodesulfov...
WP_015750757    3 KSMTGYGR---WSGQ-SAaLAQTWEIKSVNGKQLSIRWKMPQFLSMMEQEWEKQVRETAERGRIDIQLHlHIFEaeE-LS 77  Desulfohalobiu...
WP_021762014    8 HSMTGYGRhqdCADT-GRpFRQEWEVRSVNSRHLDCKWRLPHMVRALEPALEKVLRRFASRGRIELNLHlSVEDpaF-LG 85  Megalodesulfov...
WP_011526394    3 RSMTGFGR---CVVE-DSdWTQTWEIKSVNSRYLDLKWRLPLIARSLEQKFEKIVRKYASRGRVELNLTiQQIEsqA-TP 77  Lawsonia intra...
Q72DN1          3 RSMTGFGR---CFIE-DAgWTQTWEVRSVNGRHLDVKWRLPMLLRGLEARFEKVLRRFGTRGRVDVTLSlQALGegM-QG 77  Desulfovibrio ...
Q30XS9          3 RSMTGFGR---CTKE-SPdWTQTWEIRSVNSRHLDIKWRLPGFLRGYESRLEKVLRRFGSRGRVDVSLSlDIRRqgL-DG 77  Desulfovibrio ...
WP_244829569    2 TGFGKCTK---ANEEiEV-SVEIRTLNGKSLRVRYSLPRAFNPFLNEINNIIRDYIKRGEVDLHIRYRLsPNTT--VpVT 75  Desulfurobacte...

jgi:Isop_1879  76 DYRLNLTALASYRDQLR----------QLaARDe---ETArhf-vvPWDGLLRLPGVVedgR---AAElgdLsHHEhDgg 138
WP_231865047   74 LDKSKARAAFRALAELR----------DElAPGadv-------plsLLCAVPDLFAPAgghEiaaVR------------- 123 Sorangium cell...
WP_290587266   75 INKEAFAAYAAELRQTA----------RA-AGLetdtrewdaaathAILRLPDVVSTEt--E---NVPe--EeHAA---- 132 Alistipes sp. ...
WP_015416516   78 V-SFNQTMAQAMFKQME----------QL-AESrgelFTP------DYNKVLTMASLW---R---DNG---SePDP-G-- 127 Pseudodesulfov...
WP_015750757   78 P-KLNSWIAQSMLDQLR----------QL-AEAngetPEL------DYSHLLRMPSLW---E---EPD---QtPPQ-E-- 127 Desulfohalobiu...
WP_021762014   86 M-RLNRPVALAMLEEIA----------TL-ARSqghaFTP------DYSRLLHLPACW---D---EDR---AaGNP-V-- 135 Megalodesulfov...
WP_011526394   78 L-CFNESQALSMLNAIT----------EL-AKIrgdtFSP------DYMQLLSVSSLW---E---KIE---DeNDN-N-- 127 Lawsonia intra...
Q72DN1         78 V-RFDAGQAGAMLDALS----------DL-AASrgdtYAP------DYNRLLGLTFLW---E---DAG---AePDE-E-- 127 Desulfovibrio ...
Q30XS9         78 V-SFNTRQAASMLEQLT----------GF-AAErgdaFVP------DYNRLLNLSYLW---E---DAS---GeLDE-T-- 127 Desulfovibrio ...
WP_244829569   76 INYKEALKYIQASDRIGalsgrkievsLR-----------------DLLSIPDLFMKEeidLtshSEI------------ 126 Desulfurobacte...

jgi:Isop_1879 139 eaqeaSlWNEFQPLCIEALERFQADRRREGSRMA 172
WP_231865047  124 -----AaLKLAIERAIDAMEGMCLREGEALASDM 152 Sorangium cellulosum
WP_290587266  133 -------LLAAVEEACNRLDEFRRQEGEILIADL 159 Alistipes sp. CAG:268
WP_015416516  128 -----L-AKSLTAGLENALKDWVGARTLEGDVMV 155 Pseudodesulfovibrio piezophilus
WP_015750757  128 -----I-LDSLQTGLEMALSAWNDSREREGQAMI 155 Desulfohalobium retbaense
WP_021762014  136 -----L-LHALEEGLAAALTAWNESRRQEGAVLA 163 Megalodesulfovibrio gigas
WP_011526394  128 -----I-EGRLEEGLIAALEDWNESRETEGSILY 155 Lawsonia intracellularis
Q72DN1        128 -----M-VAALEAGLAAALEDWNESREAEARALS 155 Desulfovibrio vulgaris str. Hildenborough
Q30XS9        128 -----L-LGSLEEGLAAALADWNKARETEAQALL 155 Desulfovibrio alaskensis G20
WP_244829569  127 -------LFEALKGALEEVEEARRKEGEKLKAYC 153 Desulfurobacterium thermolithotrophum
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