5AN6


Conserved Protein Domain Family
Csm2_III-A
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pfam03750: Csm2_III-A 
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Csm2 Type III-A
Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.
Links
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Statistics
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PSSM-Id: 397703
Aligned: 24 rows
Threshold Bit Score: 95.7897
Threshold Setting Gi: 119355190
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5AN6_C             7 DLKDLVRKAEEIG-RELS--Gk----LKTNQLRKFHGHLTKIWSNYIYKKKDYrdnpekfneeilNELHFMKIFLAYQVG 79  Thermotoga ...
jgi:Cpha266_2049  39 ELENLPKYAAVIAkAMKEkkKp----VTPTQLRRFYTYVKSIDLANKQTKEDEqnf------kdkYKLKFILPKIAGSSE 108 Chlorobium ...
O27153            30 KYADTGGYADVIArA-----Nn----LKTTQLRKFFSAIRSMEKKADSWKSIE------------ADFYLLKPQLANARG 88  Methanother...
jgi:Sfum_1348     56 DPSLVDARAASWA-SSF---Rd----LKSTQMRRFYDEFKAIERKILRGKVEEqvanf---erdmALVMMFKAKAVYAEK 124 Syntrophoba...
jgi:Tlie_0235     34 DYSRLVSIGKEVA-QEI---Kk----LSSNQLRKFHAYIVRFAMMYEIQKKCGdrds----nesfQKIQLLRYHLHYAAK 101 Thermovirga...
jgi:Maeo_1082     51 NIGILINKAEKFA-EEI---Ka----MPSSKLRDFYDYVVQIDESMSEDEDNNnn--------wyLKLMLLKPKMAYQAS 114 Methanococc...
Q59064            24 NANEIIDIAENLA-KEF---Eq----IPATKMRDFYDYVLRIDEKNen---------------wyKELVLLKPKLAYNYG 80  Methanocald...
CDE69454          15 VMQVLCNKTDKRG-KKV---Sp----VTTSKIRNLLAMTADIYNEVVNQPVETlsa------eikGQINYMKIHFIYSAG 80  Clostridium...
CDB29559          34 vPENYVEQAENVM-YDLRnrRs----ITTTKIRNLFSLVVDICSEEELRTESTlqd------ksvARLKRMHVRVIYESG 102 Firmicutes ...
CDC18597          15 SKTNYVEIAEERI-KGLDkdSkgvilIKTNKIRNILSLMNELYAMIKKDRNEKlsv------etqSHVQYVRMKLAYEAG 87  Eubacterium...

5AN6_C            80 Rd-----iEGISELKEI--LEPLI--DEIKTP------DEFEKFKKFYDAILAYHKFHS 123 Thermotoga maritima MSB8
jgi:Cpha266_2049 109 C-------ESLEDLYKV--LNACVngDKIITV------KDLRLFMEFFEAILDYHSTFK 152 Chlorobium phaeobacteroides DSM 266
O27153            89 Rd------LIPEGFYEV--MKKMM--DKVDRGdddekiENFRVFVRFLESIVAYHKFYN 137 Methanothermobacter thermautotro...
jgi:Sfum_1348    125 Rk------VSPREFTQF--IFDHM--ASIKDL------KDFQAFIKVFEAVVAFHRFYA 167 Syntrophobacter fumaroxidans MPOB
jgi:Tlie_0235    102 Kvqs--skSDAKNLAAL--LGAAV--EKVKQP------EDLLRLKYLSEAIVAYHKSYK 148 Thermovirga lienii DSM 17291
jgi:Maeo_1082    115 KetnkgkqIALKMLEKE--FTKIL--DTIKNDk-----NKFKNFKTFFEAVVAYHKGHN 164 Methanococcus aeolicus Nankai-3
Q59064            81 KetnrrkkEALEKLAGT--FSEII--DKIDNDl-----NKFKNFKTFFEALVAYHKIYA 130 Methanocaldococcus jannaschii DS...
CDE69454          81 Re------PKVRELLEEadILTHI--DEIGDSr-----KQYILFSRYMEALVAYRKFYG 126 Clostridium sp. CAG:277
CDB29559         103 Rd------SGTKEFVEKtkLLEYL--KWIGNDr-----KRLIRFTRYMEALVAFHRYFG 148 Firmicutes bacterium CAG:137
CDC18597          88 Rd------ANVKKFLNDvrLIGYL--KIVKDSr-----AKLLLICNYTEALVAYHKYYT 133 Eubacterium sp. CAG:274
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