1V6T,2DFA,2XU2,1XW8


Conserved Protein Domain Family
LamB_YcsF
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pfam03746: LamB_YcsF (This model is not part of the current CDD release)
LamB/YcsF family
This family includes LamB. The lam locus of Aspergillus nidulans consists of two divergently transcribed genes, lamA and lamB, involved in the utilisation of lactams such as 2-pyrrolidinone. Both genes are under the control of the positive regulatory gene amdR and are subject to carbon and nitrogen metabolite repression. The exact molecular function of the proteins in this family is unknown.
Links
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Statistics
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PSSM-Id: 515778
Aligned: 323 rows
Threshold Bit Score: 216.503
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1V6T_A                            4 DLNSDLGESFGRYKLG--LDEEVMKYITSANVACGWHAGDPLVMRKTVRLAKENDVQVGAHPGYPDLMGFGRRYMK-LTP 80  Pyrococcus horikoshii OT3...
Q5NI64                            3 LINCDLGER----GVAhpIDDRLVDYIDIANIACGGHAGDKASVDYYVNLCKGKNVKITAHISYPDKQNFGRKVID-IDH 77  Francisella tularensis subsp. tularensis...
WP_013042979                      4 LLNCDLGENEPTT-----RTAELLALVDAANICCGVHAGSAAKTRETIGLAKRAGVLIGVHPG--MAAAGGRGAEL-PDP 75  Coraliomargarita akajimensis...
EAR15526                          9 DLNCDVGEGVG-------NEQELFPHISSCNIACGGHAGNRESMKEIVTLAGKAGVRAGAHPSYPDRENFGRKHMQ-LTA 80 
jgi:Belba_2886                   31 DINCDLGEGMP-------NDSMLMPYLGSCNIACGGHFGDLETIKSAILLAKENHVKVGAHPSYPDKENFGRKSLK-IDL 102
WP_008200361                      6 eINCDLGE-------GisHEADIFPWIDAASIACGGHFGDKNTISKSLDLAIQFNTKVGAHPSYPDPENFGRKSIK-IAP 77  Algoriphagus machipongonensis...
WP_013187529                      5 DINCDLGE-------GglYDHKLMPLITSCSIACGGHFGNIDTMNSAVVLAKQHQVKIGAHPSYPDHQNFGRVSLKdMPK 77  Croceibacter atlanticus...
dbos:1099484000100_PB2503_04707  10 DLNADVGEGMG-------DDRALIPLVSSVNIACGGHAGTPETMRRAVDLADRSGVGIGAHPAYPDREGFGRRSMD-LSP 81 
WP_013407996                      4 EINCDMGERAETQ-----LDLELMPYVDAVNISCGYHAGSLDILRTTIKNAQIHGLKIGAHPGFKDPEHFGRRKIF-LSK 77  Leadbetterella byssophila...
jgi:HIMB59_00005850               7 NFNSDLAERDLSFYQSv--DLPLITQINSANIGCLYHGGVEEVVQKATQECHHQGVSIGAHISFLDKDNFGRTPMD-WSE 83 

1V6T_A                           81 EEARNYILYQVGALYAFAKAEGLELQHVKPHGALYNAMVKEEDLARAVIEGILDFDkdliLVTLSNSRVADIAEEMGLKV 160 Pyrococcus horikoshii OT3...
Q5NI64                           78 NVLCESFDQQFALFDSE-------IKAIKPHGVLYNQLNVDQELAKTFIQWCIKNNidelLVSPFGV-VAEYAKDKGIKT 149 Francisella tularensis subsp. tularensis...
WP_013042979                     76 VALSSLLREQCGFFAEAAAELDASIHHIKLHGSLYSAVEQDEELAQIYADVLRDYpd-wkVFSLANGTFGRRAASDGHPV 154 Coraliomargarita akajimensis...
EAR15526                         81 RELEESLLEQLQLLDEVAAAAGVPLHHIKAHGALYNDLAANPALAREYLRILTPYResrvLFVPAGSDLMRRALSLGYRV 160
jgi:Belba_2886                  103 KTLEESLLDQITNFEKVCFDQNIDMHHIKPHGALYNDLAKDEKLASFFLTLIQKFFqdipLYTPPNSIIFQLAPQFNIKT 182
WP_008200361                     78 TELLDSLREQIDLFVEIAQLKGLPMDHIKLHGALYNDAAKNPGLAELLSNFLTLNYpnvpIFTSPNSELEKFSLKKLIPI 157 Algoriphagus machipongonensis...
WP_013187529                     78 QDLKDSLLNQLHTLNDIASFHNYPLTHIKPHGALYNDANVDEPIAKLIIETVQEFNseipIFVAPESIISKIVKGK-IDM 156 Croceibacter atlanticus...
dbos:1099484000100_PB2503_04707  82 TALREALISQIEALVDVT--TREAVGHVKPHGALYNDAHKDKALAALMVDVLRMTlpsarLVGPPGGELEAAAMAVGLVF 159
WP_013407996                     78 KEIYTLVREQLEIFSNEC----GNFSHVKPHGALYNMSADMEDYAEAIAKAVLDHNpdleLYGLANSISIKKAEELGLKT 153 Leadbetterella byssophila...
jgi:HIMB59_00005850              84 ELIHSLINEQFSILSNL-KDPQISITHLKPHGALNNMACKDLALAQVIVSYVKQHYpeliMLAPVLSELAKASQAMGLVT 162

1V6T_A                          161 AHEVFADRAYNPDGT----LVPRGRPGAVIEDKEEIAERVISMVKdGGIRAI-NGEWVDL-KVDTICVHGDNPKAVEITS 234 Pyrococcus horikoshii OT3...
Q5NI64                          150 IKESFAERGYMLDNHnnpmLIPRGQPNAEIEDVALAVAQYNQL-KqGFVKIA--GEEIAF-KSQTICIHSDSSIALELAQ 225 Francisella tularensis subsp. tularensis...
WP_013042979                    155 VGEIFADRAYLDNGA----LMPRSQAGALIEDVELAVERFRNWLVtRQMQTGlTG-SILL-DAETVCVHSDSPNALELLR 228 Coraliomargarita akajimensis...
EAR15526                        161 WGEAFADRAYNADGS----LVARSEPGAVLTEPSRVFRQVRDLVLrGRATTP-EGREIKL-SPDTICIHGDTPGALEILM 234
jgi:Belba_2886                  183 VLEVFADRSYEDDLR----LVDRSHSKALLTEVVDVKEHIHSMIFdQKVKTI-SGKKIDI-KAETLCIHGDNPSALPILQ 256
WP_008200361                    158 RKEVFADRAYNPDFS----LVSRNVEGALFTDIEQIKNHLTPLLEkGYISAI-NGSKLPI-SADTLCFHGDNPGLVHFLP 231 Algoriphagus machipongonensis...
WP_013187529                    157 ITEGFADRSYNTDYT----LKSRKLDGAVLKLKEEVLRHVLQILKyNRVEVS-KDSFIPI-TIETLCMHSDTENSVKLLD 230 Croceibacter atlanticus...
dbos:1099484000100_PB2503_04707 160 TAEGFVDRAYAEDGS----LIPRSEEGAVLVSEADRLRQAISLGLrHEVETL-SGETIGL-RVQTLCLHGDSDGAVASAR 233
WP_013407996                    154 CSEGFADRAYLQNGL----LAPREREGSVLTDRQRIEIQFKAFLEgSALPDInE-KPGPIiRASTLCVHSDSPHALKTAQ 228 Leadbetterella byssophila...
jgi:HIMB59_00005850             163 ALEVFADRTYEDDGT----LTPRSIEGSLITDPSQASDHVKKMIEeKAIISR-SGKKLPT-TFHSICLHSDTPNSVEISN 236

1V6T_A                          235 YIRKVLE 241 Pyrococcus horikoshii OT3
Q5NI64                          226 ELyknkg 232 Francisella tularensis subsp. tularensis
WP_013042979                    229 KLQNckk 235 Coraliomargarita akajimensis
EAR15526                        235 YLSLELp 241
jgi:Belba_2886                  257 MIHSNFs 263
WP_008200361                    232 EIRKiww 238 Algoriphagus machipongonensis
WP_013187529                    231 DLHKFLi 237 Croceibacter atlanticus
dbos:1099484000100_PB2503_04707 234 AVRAALL 240
WP_013407996                    229 WLNelil 235 Leadbetterella byssophila
jgi:HIMB59_00005850             237 QICillh 243
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