5DLC,3O6D


Conserved Protein Domain Family
PdxJ
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pfam03740: PdxJ (This model is not part of the current CDD release)
Pyridoxal phosphate biosynthesis protein PdxJ
Members of this family belong to the PdxJ family that catalyzes the condensation of 1-deoxy-d-xylulose-5-phosphate (DXP) and 1-amino-3-oxo-4-(phosphohydroxy)propan-2-one to form pyridoxine 5'-phosphate (PNP). This reaction is involved in de novo synthesis of pyridoxine (vitamin B6) and pyridoxal phosphate.
Links
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Statistics
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PSSM-Id: 515774
Aligned: 289 rows
Threshold Bit Score: 234.567
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5DLC_A         16 LLGVNIDHVATLRQARGTR-YPDPVKAALDAEEAGADGITVHLREDRRHIQERDVRVLKE---VLQT------------- 78  Pseudomonas ae...
7_pfamImport    1 KLSVNVNKIAVLRNSRGGE-LPSVLDAARACLDAGAHGITVHPRPDRRHIHAEDALALAE---LTQAhg----------v 66 
Q8PEG8          4 HLSVNVNKIAVLRNSRGGQ-DPDVVQAARSCIAAGAHGITVHPRPDQRHIRADDVYALST---LTRMhg----------v 69  Xanthomonas ca...
DSC:DSC_01045   4 ALSVNVNKVAVLRNSRGGG-EPDVVRAARTCLRAGAHGITVHPRPDRRHITAEDVLALAG---LTAQfq----------v 69 
WP_013533706    3 RLSVNVNKIAVLRNSRGGG-EPDVLAAARACLAAGAHGITVHPRPDRRHVVAEDLAPLAD---ATARyg----------v 68  Pseudoxanthomo...
B0SJ25          3 QLSVNVNKIATLRNSRGGS-LPSVLKLSELILDSGAHGITVHPRSDERHITKQDVFELQE---FLRTynekitklgiskk 78  Leptospira bif...
Q8F5Z9          4 KLSVNINKIATLRNSRGGN-IPDLSYFANLVLKAGAHGITVHPREDERHIRKEDVFVLKE---FIDSynrkn----ntni 75  Leptospira int...
WP_012238467    2 KLSVNVNKIALLRNSRGHD-APNVLSFARKIVDYGAHGITIHPRADRRHITPDDARAVTRhitTV--------------- 65  Sorangium cell...
WP_012828361    4 NLSVNLNKVALLRNSRGAD-NPCPVRAAEACIAAGAPGLTLHWREDERHTREGDVRALRK---LADErg----------v 69  Haliangium och...
WP_006930944    3 RLAVDIDPIAFVRNSF-NDkYPDPIQAVVLAELGGAESIVAYLHDNQKTVKETDIVLLKH---IVKT------------- 65  Caldithrix abyssi

5DLC_A         79 RMNFEMGV-------TEEMLAFAEEIRPAHSCLVPERREELTTEGGLDV--AGQEQRIRDAVRRLAAVGSEVSLFIDPDP 149 Pseudomonas ae...
7_pfamImport   67 EFNIEGNPfaplrpgYPGLIALCAQARPTQATLVPDGDSQLTSDHGFDF--GRDSDRLRPLIAELKALGCRVSLFVDADN 144
Q8PEG8         70 EFNIEGNPfappragYPGLLELCRATRPQQVTLVPDGDGQLTSDHGVDF--ARDGARLAPLIAAFKTLGCRVSLFVDAGN 147 Xanthomonas ca...
DSC:DSC_01045  70 ELNIEGNPfapprqgYPGLLALCERARPAQVTLVPDSDGQLTSDHGFDF--TGDTIQLGRLVAHFKALGCRVSLFVDAGC 147
WP_013533706   69 EFNIEGNPfappregYPGLLALCEQVRPAQVTLVPDSDGQLTSDHGFAL--EGDLAGLADQVAGFAALGCRVSLFVDAGN 146 Pseudoxanthomo...
B0SJ25         79 EYNIEGEP-------SERFLDLVLKAKPDQATLVPVKPGEITSDHGFQFadQKTFSTLKPIVEAIRKEGIRVSLFMETDF 151 Leptospira bif...
Q8F5Z9         76 EYNLEGEP-------SPRFLDLVLKTKPDQATLVPVTPGEITSDHGFDF--EKDMEILSEYSKILKKDKIRVSLFVETGL 146 Leptospira int...
WP_012238467   66 ETNFEGDL-------REEFLDLTLELRPTQCTLVPVTPGELTSHRGWDV--AKWRFVLQPVVKRLKEEGIRTSLFVEADP 136 Sorangium cell...
WP_012828361   70 EFNLEGDA-------RPAIVAIALELRVTQFTLVPVTPGEITSDHGWDL--PREHDTLAPILERCRAAGVRTSIFMDPVA 140 Haliangium och...
WP_006930944   66 YLNIRCNL-------TEENVRKLLRIKPDMVTFVAPGELHDIAPHPLNV--DMYPTQLQDFIIELRTNGILSSVLIEPQV 136 Caldithrix abyssi

5DLC_A        150 RQIEASARVGAPAIELHTGRYADAED-P-EEQ-AREL-QRVREGVALGRSLGLIVNAGHGLHYHNVEP-VAAIDGINELN 224 Pseudomonas ae...
7_pfamImport  145 PDLAIAAELGADRIELYTGPYAAAFerGdGAA-ATMA-ARFAAAARRAQTLGLGVNAGHDLSQANLDMfLAQVPQVLEVS 222
Q8PEG8        148 PEIAQAAALGADRIELYTGPYAEAHhhGq--S-QPSL-ALFADAARRAHAAGLGINAGHDLSQHNLADfLAGVPDVLEVS 223 Xanthomonas ca...
DSC:DSC_01045 148 VGLERAAAMGADRIELYTGPYAQGWaaGa--P-DPAL-AACRATAQEAQLLGLQVNAGHDLSQDNLGMfLAGVPQVQEVS 223
WP_013533706  147 PHVERVAEVGAHRIEIYTGPYAEAHatGr--A-GEAL-ALCAETARRAQAAGLGVNAGHDLSQANLGDfLAGVPGVEEVS 222 Pseudoxanthomo...
B0SJ25        152 TFYDQVVALGAERIELYTGPFAHAFD-LsEEKgKEIF-TDYQRAAIEANKLGLAVNAGHDLDTNNLRv-FAKLPYLKEVS 228 Leptospira bif...
Q8F5Z9        147 KNLKLASLSGADRVEFYTGPFAEAFD-HsPQIgKKRFeTEYVPAATEILNQKMGINAGHDLDHENLKI-FSKLPGLQEVS 224 Leptospira int...
WP_012238467  137 AVVPLVAEMGADRIEIYTGPYAQAFd---RGEhRAEL-DKIVATVRAAVAAGVGINAGHDLTVENLAPlVREAPQIQEVS 212 Sorangium cell...
WP_012828361  141 ENMAAAARTGVDRVEIYTEPYAAAFg---TATqDQAL-AQTAAAVAAARARGLGVNAGHDLDLYNLPLlARAAPGIDEVS 216 Haliangium och...
WP_006930944  137 EQVKLAGKLEFDYVELDATGLANAED-MdSE--IALL-QELDNLSLAANKLGMGVNISGGIGYDNIRD-ITKMENIEDII 211 Caldithrix abyssi

5DLC_A        225 IGHAIVAHALFVGFRQAVAEMKALM 249 Pseudomonas aeruginosa
7_pfamImport  223 IGHALIGEALYAGLDATVKAYLAVL 247
Q8PEG8        224 IGHALVGEALYQGLEPTVRAYLAII 248 Xanthomonas campestris pv. campestris str. ATCC 33913
DSC:DSC_01045 224 IGHALISEALYEGLETTVRRYLAII 248
WP_013533706  223 IGHALIGEALYAGLDATVRAYLAIL 247 Pseudoxanthomonas suwonensis
B0SJ25        229 IGHRLMAQSLVDGLETTVKSYLKVL 253 Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'
Q8F5Z9        225 IGHRLISRALETGIDQSVKDYLQAL 249 Leptospira interrogans
WP_012238467  213 IGHHLVAHALEVGMKQSVRDYLAAV 237 Sorangium cellulosum
WP_012828361  217 IGHALIADALYWGLERTVRAYLDAa 241 Haliangium ochraceum
WP_006930944  212 VGKPLFSKSLAIGFEQAVRDLIALM 236 Caldithrix abyssi
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