2FMM


Conserved Protein Domain Family
ENT
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pfam03735: ENT (This model is not part of the current CDD release)
ENT domain
This presumed domain is named after Emsy N Terminus (ENT). Emsy is a protein that is amplified in breast cancer and interacts with BRCA2. The N terminus of this protein is found to be similar to other vertebrate and plant proteins of unknown function. This domain has a completely conserved histidine residue that may be functionally important.
Links
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Statistics
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PSSM-Id: 515769
Aligned: 31 rows
Threshold Bit Score: 80.7078
Created: 13-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
Download Cn3D
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2FMM_E        11 KRILRKLELEAYAGVISALRAQGD-LT------KEKKDLLGELSKVLSISTERHRAEVRRAVNDERLTTIAHNMSGP 80  human
VDC62915      50 D--LNKLKKNAYYEVLKAFLAESStISgvnayyEPRIMFMKELKKELNIDHDTHADCHKRVKTDTLVQELR-GTSSE 123
Q9M2Q2        35 ERKLQNLQRKAFYNLLQTFAFENStMS------NKRTEIIGKLMNEWGIANETHISFADQI--QKKLLTLKQTKHSG 103 thale cress
XP_002876447  80 KETLQELQKKAFYSLLQAFALETStMS------NKRTQIIEKLMNEWGIANETQISFADQI--QKKLLTLQQMKDSD 148
EFH52707      45 NEKLRELQRKAYFYVLHAFRAESPaIS------SQGITIVKELMKELKIDLNTHQNYENIIKDDPMVQQLRNVSLAS 115
Q9M2Q1        45 KVKLSMLQDRAYYYVLHAFKAESPaIS------SSRIVIMQELLKELKIEYKTHQTYHNAIEADPMVLQLRNVSLAS 115 thale cress
XP_002500510   6 GEQVRKLELDAYQAFLKVTAVTG--MS------WERDDLATKLRQELNISNDDHTRIREKLSDDERIKTIRENWKQR 74 
Q01CZ5         4 GASVKKLEQNAYAAILKAMAVTG--LT------WEREEFLGRLRLELNVSSEDHMRLREQMDSDENVSRLRHGYAEH 72  Ostreococcus tauri
Q08A72        58 EAQIHQIEKEAYISVLRAFKAQGDaIS------WEKESVITELRKELSLSNEEHRELLGRVNSDDTIRRIREWRQSG 128 thale cress
AAL87186      50 ESEIHQVEQEAYTGVLRAFKVQSDaIS------WEKESLITELRKELRVSDDEHRELLNKVNEDVAIRRMREFRQGG 120
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